Search Results - "Dulka, Brooke N"
-
1
Chemogenetic activation of an infralimbic cortex to basolateral amygdala projection promotes resistance to acute social defeat stress
Published in Scientific reports (23-04-2020)“…Tremendous individual differences exist in stress responsivity and social defeat stress is a key approach for identifying cellular mechanisms of stress…”
Get full text
Journal Article -
2
Age-Related Memory Impairment and Sex-Specific Alterations in Phosphorylation of the Rpt6 Proteasome Subunit and Polyubiquitination in the Basolateral Amygdala and Medial Prefrontal Cortex
Published in Frontiers in aging neuroscience (09-04-2021)“…Aging is marked by an accumulation of damaged and modified brain proteins, and the ubiquitin-proteasome system (UPS) is important for cellular protein…”
Get full text
Journal Article -
3
Age-Related Memory Impairment Is Associated with Increased zif268 Protein Accumulation and Decreased Rpt6 Phosphorylation
Published in International journal of molecular sciences (28-07-2020)“…Aging is associated with cognitive decline, including impairments in the ability to accurately form and recall memories. Some behavioral and brain changes…”
Get full text
Journal Article -
4
Activity of a vmPFC-DRN Pathway Corresponds With Resistance to Acute Social Defeat Stress
Published in Frontiers in neural circuits (16-10-2020)“…The ventromedial prefrontal cortex (vmPFC) plays a critical role in stress resilience through top-down inhibition of key stress-sensitive limbic and hindbrain…”
Get full text
Journal Article -
5
GABA-Mediated Presynaptic Inhibition Is Required for Precision of Long-Term Memory
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-04-2014)“…Though much attention has been given to the neural structures that underlie the long-term consolidation of contextual memories, little is known about the…”
Get full text
Journal Article -
6
Metabolomics reveals distinct neurochemical profiles associated with stress resilience
Published in Neurobiology of stress (01-12-2017)“…Acute social defeat represents a naturalistic form of conditioned fear and is an excellent model in which to investigate the biological basis of stress…”
Get full text
Journal Article -
7
-
8
Social Dominance Modulates Stress-induced Neural Activity in Medial Prefrontal Cortex Projections to the Basolateral Amygdala
Published in Neuroscience (15-09-2018)“…•The retrograde tracer CTB labeled PL, IL, and vHPC efferents to the hamster amygdala.•Dominants have elevated c-Fos in the PL and IL during acute social…”
Get full text
Journal Article -
9
Age-related memory deficits are associated with changes in protein degradation in brain regions critical for trace fear conditioning
Published in Neurobiology of aging (01-07-2020)“…Brain aging is accompanied by an accumulation of damaged proteins, which results from deterioration of cellular quality control mechanisms and decreased…”
Get full text
Journal Article -
10
Gonadal steroid hormone receptors in the medial amygdala contribute to experience-dependent changes in stress vulnerability
Published in Psychoneuroendocrinology (01-07-2021)“…Social experience can generate neural plasticity that changes how individuals respond to stress. Winning aggressive encounters alters how animals respond to…”
Get full text
Journal Article -
11
RETRACTED: BNDF heterozygosity is associated with memory deficits and alterations in cortical and hippocampal EEG power
Published in Behavioural brain research (14-08-2017)“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal)…”
Get full text
Journal Article -
12
Dominance status alters restraint-induced neural activity in brain regions controlling stress vulnerability
Published in Physiology & behavior (01-10-2017)“…Abstract Understanding the cellular mechanisms that control resistance and vulnerability to stress is an important step toward identifying novel targets for…”
Get full text
Journal Article -
13
Proteolytic Cleavage of ProBDNF into Mature BDNF in the Basolateral Amygdala Is Necessary for Defeat-Induced Social Avoidance
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-04-2016)“…Brain-derived neurotrophic factor (BDNF) is essential for memory processes. The present study tested whether proteolytic cleavage of proBDNF into mature BDNF…”
Get full text
Journal Article -
14
Phenotypic responses to social defeat are associated with differences in cued and contextual fear discrimination
Published in Behavioural processes (01-09-2015)“…•Following social defeat stress, mice exhibit two distinct phenotypes characterized as being either susceptible or resistant to the defeat-induced avoidance…”
Get full text
Journal Article -
15
BNDF heterozygosity is associated with memory deficits and alterations in cortical and hippocampal EEG power
Published in Behavioural brain research (14-08-2017)“…Brain derived neurotrophic factor (BDNF) plays a pivotal role in structural plasticity, learning, and memory. Electroencephalogram (EEG) spectral power in the…”
Get full text
Journal Article