Search Results - "Duliege, Anne‐Marie"

Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo‐controlled trials by Bussel, James, Arnold, Donald M., Grossbard, Elliot, Mayer, Jiří, Treliński, Jacek, Homenda, Wojciech, Hellmann, Andrzej, Windyga, Jerzy, Sivcheva, Liliya, Khalafallah, Alhossain A., Zaja, Francesco, Cooper, Nichola, Markovtsov, Vadim, Zayed, Hany, Duliege, Anne‐Marie

“…Spleen tyrosine kinase (Syk) signaling is central to phagocytosis‐based, antibody‐mediated platelet destruction in adults with immune thrombocytopenia (ITP)…”
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Long‐term fostamatinib treatment of adults with immune thrombocytopenia during the phase 3 clinical trial program by Bussel, James B., Arnold, Donald M., Boxer, Michael A., Cooper, Nichola, Mayer, Jiri, Zayed, Hany, Tong, Sandra, Duliege, Anne‐Marie

“…Two randomized, double‐blind, placebo‐controlled studies demonstrated responses (≥50 000/μL) to fostamatinib in adults with long‐standing immune…”
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A Peptide-Based Erythropoietin-Receptor Agonist for Pure Red-Cell Aplasia by Macdougall, Iain C, Rossert, Jerome, Casadevall, Nicole, Stead, Richard B, Duliege, Anne-Marie, Froissart, Marc, Eckardt, Kai-Uwe

“…This trial enlisted 14 patients with pure red-cell aplasia and antierythropoietin antibodies that were induced by treatment with conventional…”
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Dose-finding Study of Peginesatide for Anemia Correction in Chronic Kidney Disease Patients by Macdougall, Iain C, Wiecek, Andrzej, Tucker, Beatriz, Yaqoob, Magdi, Mikhail, Ashraf, Nowicki, Michal, MacPhee, Iain, Mysliwiec, Michal, Smolenski, Olgierd, Sułowicz, Władysław, Mayo, Martha, Francisco, Carol, Polu, Krishna R, Schatz, Peter J, Duliege, Anne-Marie

“…Peginesatide is a synthetic, PEGylated, investigational, peptide-based erythropoiesis-stimulating agent. We report the first assessment of its efficacy and…”
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Population Pharmacokinetics and Pharmacodynamics of Peptidic Erythropoiesis Receptor Agonist (ERA) in Healthy Volunteers by Woo, Sukyung, Krzyzanski, Wojciech, Duliege, Anne-Marie, Stead, Richar B., Jusko, Willia J.

“…Peptidic erythropoiesis receptor agonist is a synthetic, PEGylated peptide that can promote red blood cell production upon binding to the erythropoietin…”
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Safety and Immunogenicity of a Canarypox-Vectored Human Immunodeficiency Virus Type 1 Vaccine with or without gp120: A Phase 2 Study in Higher- and Lower-Risk Volunteers by Belshe, Robert B., Stevens, Cladd, Gorse, Geoffrey J., Buchbinder, Susan, Weinhold, Kent, Sheppard, Haynes, Stablein, Donald, Self, Steve, McNamara, James, Frey, Sharon, Flores, Jorge, Excler, Jean Louis, Klein, Michel, El Habib, Raphaelle, Duliege, Anne-Marie, Harro, Clayton, Corey, Lawrence, Keefer, Michael, Mulligan, Mark, Wright, Peter, Celum, Connie, Judson, Frank, Mayer, Kenneth, McKirnan, David, Marmor, Michael

“…Live attenuated viral vectors that express human immunodeficiency virus (HIV) antigens are being developed as potential vaccines to prevent HIV infection. The…”
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Clade B-Based HIV-1 Vaccines Elicit Cross-Clade Cytotoxic T Lymphocyte Reactivities in Uninfected Volunteers by Ferrari, Guido, Humphrey, Will, McElrath, M. Juliana, Excler, Jean-Louis, Duliege, Anne-Marie, Clements, Mary Lou, Corey, Lawrence C., Bolognesi, Dani P., Weinhold, Kent J.

“…A fundamental goal of current strategies to develop an efficacious vaccine for AIDS is the elicitation of broadly reactive cytotoxic T lymphocyte (CTL)…”
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Effect of Previous or Simultaneous Immunization with Canarypox Expressing Cytomegalovirus (CMV) Glycoprotein B (gB) on Response to Subunit gB Vaccine plus MF59 in Healthy CMV-Seronegative Adults by Bernstein, David I., Schleiss, Mark R., Berencsi, Klara, Gonczol, Eva, Dickey, Michelle, Khoury, Phil, Cadoz, Michel, Meric, Claude, Zahradnik, John, Duliege, Anne-Marie, Plotkin, Stanley

“…Development of a vaccine for prevention of congenital cytomegalovirus (CMV) disease is a priority. This study evaluated a “prime-boost” strategy by comparing…”
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Fostamatinib disodium hexahydrate: a novel treatment for adult immune thrombocytopenia by McBride, Ali, Nayak, Pratima, Kreychman, Yuliya, Todd, Leslie, Duliege, Anne-Marie, Mehta, Amit R

“…Immune thrombocytopenia (ITP) is an autoimmune disease associated with substantial heterogeneity and varying outcomes. Significant bleeding, including…”
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Peginesatide for Anemia in Patients with Chronic Kidney Disease Not Receiving Dialysis by Macdougall, Iain C, Provenzano, Robert, Sharma, Amit, Spinowitz, Bruce S, Schmidt, Rebecca J, Pergola, Pablo E, Zabaneh, Raja I, Tong-Starksen, Sandra, Mayo, Martha R, Tang, Hong, Polu, Krishna R, Duliege, Anne-Marie, Fishbane, Steven

“…Two studies compared peginesatide with darbepoetin in patients with CKD and anemia who were not receiving dialysis. The agents were similar in increasing and…”
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Peginesatide in Patients with Anemia Undergoing Hemodialysis by Fishbane, Steven, Schiller, Brigitte, Locatelli, Francesco, Covic, Adrian C, Provenzano, Robert, Wiecek, Andrzej, Levin, Nathan W, Kaplan, Mark, Macdougall, Iain C, Francisco, Carol, Mayo, Martha R, Polu, Krishna R, Duliege, Anne-Marie, Besarab, Anatole

“…In two randomized, controlled studies involving patients undergoing long-term hemodialysis, peginesatide, a synthetic peptide-based erythropoiesis-stimulating…”
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Safety and Immunogenicity of Combinations of Recombinant Subtype E and B Human Immunodeficiency Virus Type 1 Envelope Glycoprotein 120 Vaccines in Healthy Thai Adults by Pitisuttithum, Punnee, Nitayaphan, Sorachai, Thongcharoen, Prasert, Khamboonruang, Chirasak, Kim, Jerome, de Souza, Mark, Chuenchitra, Thippawan, Garner, Robin P., Thapinta, Darawan, Polonis, Victoria, Ratto-Kim, Silvia, Chanbancherd, Penprapa, Chiu, Joseph, Birx, Deborah L., Duliege, Anne-Marie, McNeil, John G., Brown, Arthur E.

“…Safety and immunogenicity of 2 recombinant human immunodeficiency virus (HIV) type 1 envelope glycoprotein (gp) 120 vaccines derived from SF2 (subtype B) and…”
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An open-label, sequential, dose-finding study of peginesatide for the maintenance treatment of anemia in chronic hemodialysis patients by Besarab, Anatole, Zeig, Steven N, Martin, Edouard R, Pergola, Pablo E, Whittier, Frederick C, Zabaneh, Raja I, Schiller, Brigitte, Mayo, Martha, Francisco, Carol A, Polu, Krishna R, Duliege, Anne-Marie

“…Peginesatide is a peptide-based erythropoiesis-stimulating agent that was designed and engineered to stimulate specifically the erythropoietin receptor dimer…”
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Human Immunodeficiency Virus Type 1 (HIV-1) gp120–Specific Antibodies in Neonates Receiving an HIV-1 Recombinant gp120 Vaccine by McFarland, Elizabeth J., Borkowsky, William, Fenton, Terry, Wara, Diane, McNamara, James, Samson, Pearl, Kang, Minhee, Mofenson, Lynne, Cunningham, Coleen, Duliege, Anne-Marie, Sinangil, Faruk, Spector, Stephen A., Jimenez, Eleanor, Bryson, Yvonne, Burchett, Sandra, Frenkel, Lisa M., Yogev, Ram, Gigliotti, Francis, Luzuriaga, Katherine

“…Infants born to human immunodeficiency virus type 1 (HIV-1)–infected mothers were immunized at birth and at ages 4, 12, and 20 weeks with low-, medium-, or…”
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Peginesatide for Anemia in Chronic Kidney Disease by Tomoda, Haruo, Macdougall, Iain C, Fishbane, Steven, Duliege, Anne-Marie

“…To the Editor: Macdougall et al. (Jan 24. issue) 1 report that cardiovascular events were increased with peginesatide in patients who were not receiving…”
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Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers by Stead, Richard B., Lambert, John, Wessels, Dawie, Iwashita, Julie S., Leuther, Kerstin K., Woodburn, Kathryn W., Schatz, Peter J., Okamoto, Douglas M., Naso, Robert, Duliege, Anne-Marie

“…Hematide is an investigational pegylated synthetic peptide that stimulates erythropoiesis in animal models and is being developed for the treatment of anemia…”
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Lymphoproliferative Responses to Recombinant HIV-1 Envelope Antigens in Neonates and Infants Receiving gp120 Vaccines by Borkowsky, William, Wara, Diane, Fenton, Terry, McNamara, James, Kang, Minhee, Mofenson, Lynne, McFarland, Elizabeth, Cunningham, Coleen, Duliege, Anne-Marie, Francis, Donald, Bryson, Yvonne, Burchett, Sandra, Spector, Stephen A., Frenkel, Lisa M., Starr, Stuart, Van Dyke, Russell, Jimenez, Eleanor

“…Children of mothers infected with human immunodeficiency virus type 1 (HIV-1) were immunized at birth and at 1, 3, and 5 months with 1 of 3 doses of…”
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Randomized Trial on the Effect of an Oral Spleen Tyrosine Kinase Inhibitor in the Treatment of IgA Nephropathy by Tam, Frederick W.K., Tumlin, James, Barratt, Jonathan, Rovin, Brad H., Roberts, Ian S.D., Roufosse, Candice, Cook, H. Terence, Bhangal, Gurjeet, Brown, Alison L., Busch, Martin, Dudhiya, Fayaz, Duliege, Anne-Marie, Fraser, Donald J., Gale, Daniel P., Huang, Chiu-Ching, Lai, Ping-Chin, Lee, Meng, Masuda, Esteban S., McAdoo, Stephen P., Rosenkranz, Alexander R., Sommerer, Claudia, Sunder-Plassmann, Gere, Szeto, Cheuk-Chun, Tang, Sydney C.W., Williamson, Don E., Willcocks, Lisa, Vielhauer, Volker, Kim, Min Jeong, Todd, Leslie, Zayed, Hany, Tong-Starksen, Sandra, Lafayette, Richard

“…We reported increased spleen tyrosine kinase (SYK) expression in kidney biopsies of patients with IgA nephropathy (IgAN) and that inhibition of SYK reduces…”
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A Subunit Cytomegalovirus Vaccine Based on Recombinant Envelope Glycoprotein B and a New Adjuvant by Pass, Robert F., Duliegè, Anne-Marie, Boppana, Suresh, Sekulovich, Rose, Percell, Sandra, Britt, William, Burke, Rae Lyn

“…A phase I randomized, double-blind, placebo-controlled trial was done with a cytomegalovirus (CMV) vaccine based on the envelope glycoprotein, gB, combined…”
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Neutralization of a Clade B Primary Isolate by Sera from Human Immunodeficiency Virus-Uninfected Recipients of Candidate AIDS Vaccines by Zolla-Pazner, Susan, Alving, Carl, Belshe, Robert, Berman, Phillip, Burda, Sherri, Chigurupati, Padmasree, Clements, Mary Lou, Duliege, Anne-Marie, Excler, Jean-Louis, Hioe, Catarina, Kahn, James, McElrath, M. Juliana, Sharpe, Sandra, Sinangil, Faruk, Steimer, Kathelyn, Walker, Mary Clare, Wassef, Nabila, Xu, Serena

“…The inability of antibodies induced by experimental human immunodeficiency virus type 1 (HIV- 1) vaccines to neutralize HIV-1 primary isolates may be due to a…”
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