Search Results - "Dulić, Vjekoslav"

Senescence from G2 arrest, revisited by Gire, Véronique, Dulić, Vjekoslav

“…Senescence was classically defined as an irreversible cell cycle arrest in G1 phase (G1 exit) triggered by eroded telomeres in aged primary cells. The…”
Get full text

Cell-Cycle Regulation Accounts for Variability in Ki-67 Expression Levels by Sobecki, Michal, Mrouj, Karim, Colinge, Jacques, Gerbe, François, Jay, Philippe, Krasinska, Liliana, Dulic, Vjekoslav, Fisher, Daniel

“…The cell proliferation antigen Ki-67 is widely used in cancer histopathology, but estimations of Ki-67 expression levels are inconsistent and understanding of…”
Get full text

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver by Wang, Jingkui, Mauvoisin, Daniel, Martin, Eva, Atger, Florian, Galindo, Antonio Núñez, Dayon, Loïc, Sizzano, Federico, Palini, Alessio, Kussmann, Martin, Waridel, Patrice, Quadroni, Manfredo, Dulić, Vjekoslav, Naef, Felix, Gachon, Frédéric

“…Diurnal oscillations of gene expression controlled by the circadian clock and its connected feeding rhythm enable organisms to coordinate their physiologies…”
Get full text

The cell proliferation antigen Ki-67 organises heterochromatin by Sobecki, Michal, Mrouj, Karim, Camasses, Alain, Parisis, Nikolaos, Nicolas, Emilien, Llères, David, Gerbe, François, Prieto, Susana, Krasinska, Liliana, David, Alexandre, Eguren, Manuel, Birling, Marie-Christine, Urbach, Serge, Hem, Sonia, Déjardin, Jérôme, Malumbres, Marcos, Jay, Philippe, Dulic, Vjekoslav, Lafontaine, Denis Lj, Feil, Robert, Fisher, Daniel

“…Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear…”
Get full text

Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts by Stein, Gretchen H., Drullinger, Linda F., Soulard, Alexandre, Dulić, Vjekoslav

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage by Bačević, Katarina, Lossaint, Gérald, Achour, Thiziri Nait, Georget, Virginie, Fisher, Daniel, Dulić, Vjekoslav

“…Although cyclin-dependent kinase 2 (Cdk2) controls the G1/S transition and promotes DNA replication, it is dispensable for cell cycle progression due to…”
Get full text

Resveratrol stimulates the metabolic reprogramming of human CD4 + T cells to enhance effector function by Craveiro, Marco, Cretenet, Gaspard, Mongellaz, Cédric, Matias, Maria I, Caron, Olivier, de Lima, Maria C Pedroso, Zimmermann, Valérie S, Solary, Eric, Dardalhon, Valérie, Dulić, Vjekoslav, Taylor, Naomi

“…The polyphenol resveratrol activates the deacetylase Sirt1, resulting in various antioxidant, chemoprotectant, neuroprotective, cardioprotective, and…”
Get more information

p16Ink4A, not only a G 1 inhibitor? by Dulic, Vjekoslav

Get full text

p16Ink4A, not only a G1 inhibitor? by Dulić, Vjekoslav

“…Comment on:  Chien WW, et al. Cell Cycle 2010; 9:3286-96…”
Get full text

Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts by Baus, Fabienne, Gire, Véronique, Fisher, Daniel, Piette, Jacques, Dulić, Vjekoslav

“…Although the Cdk inhibitor p21Waf1/Cip1, one of the transcriptional targets of p53, has been implicated in the maintenance of G2 arrest after DNA damage, its…”
Get full text

p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress by Charrier-Savournin, Fabienne Baus, Château, Marie-Thérèse, Gire, Véronique, Sedivy, John, Piette, Jacques, Dulic, Vjekoslav

“…G2 arrest of cells suffering DNA damage in S phase is crucial to avoid their entry into mitosis, with the concomitant risks of oncogenic transformation…”
Get full text

Reciprocal regulation of p21 and Chk1 controls the cyclin D1-RB pathway to mediate senescence onset after G2 arrest by Lossaint, Gérald, Horvat, Anđela, Gire, Véronique, Bačević, Katarina, Mrouj, Karim, Charrier-Savournin, Fabienne, Georget, Virginie, Fisher, Daniel, Dulić, Vjekoslav

“…Senescence is an irreversible withdrawal from cell proliferation that can be initiated after DNA damage-induced cell cycle arrest in G2 phase to prevent…”
Get full text

Confluence-induced cell cycle exit involves pre-mitotic CDK inhibition by p27Kip1 and cyclin D1 downregulation by Chassot, Anne-Amandine, Lossaint, Gerald, Turchi, Laurent, Meneguzzi, Guerrino, Fisher, Daniel, Ponzio, Gilles, Dulic, Vjekoslav

“…Tissue homeostasis requires precise control of cell proliferation and arrest in response to environmental cues. In situation such as wound healing, injured…”
Get full text

Nuclear Accumulation of p21Cip1 at the Onset of Mitosis: a Role at the G2/M-Phase Transition by Dulić, Vjekoslav, Stein, Gretchen H., Far, Dariush Farahi, Reed, Steven I.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast by Lew, D J, Dulić, V, Reed, S I

“…We have isolated a number of cDNAs derived from human mRNAs that are able to substitute for G1 cyclin genes in S. cerevisiae. Several of these encode human…”
Get more information

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest by Dulić, V, Kaufmann, W K, Wilson, S J, Tlsty, T D, Lees, E, Harper, J W, Elledge, S J, Reed, S I

“…gamma-Irradiation of human diploid fibroblasts in the G1 interval caused arrest of the cell cycle prior to S phase. This cell cycle block was correlated with a…”
Get more information

Association of human cyclin E with a periodic G1-S phase protein kinase by DULIC, V, LEES, E, REED, S. I

“…G1 cyclins control the G1 to S phase transition in the budding yeast, Saccharomyces cerevisiae. Cyclin E was discovered in the course of a screen for human…”
Get full text

Cellular senescence and the myth of Janus by Brondello, Jean-Marc, Prieur, Alexandre, Philipot, Didier, Lemaitre, Jean-Marc, Lenaers, Guy, Piette, Jacques, Dulić, Vjekoslav

“…Cellular senescence is, essentially, a permanent proliferation arrest induced by various cellular stresses or inappropriate stimuli. This arrest, which is…”
Get more information

Uncoupling between Phenotypic Senescence and Cell Cycle Arrest in Aging p21-Deficient Fibroblasts by Dulić, Vjekoslav, Beney, Georges-Edouard, Frebourg, Guillaume, Drullinger, Linda F., Stein, Gretchen H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins by Hinds, P W, Mittnacht, S, Dulic, V, Arnold, A, Reed, S I, Weinberg, R A

“…The retinoblastoma susceptibility gene (RB) product, the retinoblastoma protein (pRb), functions as a regulator of cell proliferation. Introduction of the RB…”
Get more information