Search Results - "Dulaurent, Sylvain"
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Probe Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantification of Benzodiazepines
Published in Therapeutic drug monitoring (01-08-2024)“…Legally prescribed benzodiazepines (BZDs) and designer BZDs are widely misused and must be determined in multiple contexts (eg, overdose, drug-facilitated…”
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QuEChERS sample preparation prior to LC-MS/MS determination of opiates, amphetamines, and cocaine metabolites in whole blood
Published in Analytical and bioanalytical chemistry (01-02-2016)“…Modern LC-MS/MS instruments have sensitivity and scanning velocity high enough to analyze many different compounds in single runs. Consequently, the sample…”
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Fully automated sample preparation procedure to measure drugs of abuse in plasma by liquid chromatography tandem mass spectrometry
Published in Analytical and bioanalytical chemistry (01-08-2018)“…For the analysis of drugs and pharmaceutical compounds in biological matrices, extraction procedures are typically used for LC-MS/MS analysis often requiring…”
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Unexplained Metabolic Acidosis: Alcoholic Ketoacidosis or Propylene Glycol Toxicity
Published in Journal of medical toxicology (01-04-2022)“…Introduction Severe metabolic acidosis with elevated anion and osmol gap is suggestive of toxic alcohol ingestion. The absence of detectable methanol or…”
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Pesticide contamination of workers in vineyards in France
Published in Journal of exposure science & environmental epidemiology (01-03-2006)“…In order to build tools to quantify exposure to pesticides of farmers included into epidemiological studies, we performed a field study in Bordeaux vineyards…”
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Probe electrospray ionization coupled to a quadrupole time-Of-flight: A feasibility study for the detection of cocaine and its derivatives in oral fluid
Published in Journal of pharmaceutical and biomedical analysis (15-02-2025)“…Probe Electrospray Ionization (PESI) is an atmospheric pressure ionization method that can be directly coupled with a mass spectrometer to allow ultrafast…”
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Characterization and identification of eight designer benzodiazepine metabolites by incubation with human liver microsomes and analysis by a triple quadrupole mass spectrometer
Published in International journal of legal medicine (01-07-2017)“…Designer benzodiazepines (DBZDs) have become of particular importance in the past few years. The metabolite monitoring of DBZD in biological fluids could be of…”
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Ultrafast Measurement of Metformin in the Clinical Setting Using Probe Electrospray Ionization Mass Spectrometry
Published in Journal of analytical toxicology (21-02-2023)“…Metformin (MtF) is a treatment used for type 2 diabetes. Lactic acidosis (LA) is a frequent complication that can be either induced by or associated with…”
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Assessment of tobacco, alcohol and cannabinoid metabolites in 645 meconium samples of newborns compared to maternal self-reports
Published in Journal of psychiatric research (01-07-2017)“…Abstract Prenatal psychoactive substance exposure has significant impact on neonatal health and child development and the development of reliable biomarkers is…”
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First-Line Toxicological Screening with Fully Automated Extraction
Published in Journal of analytical toxicology (12-03-2021)“…In clinical toxicology, laboratories need screening methods allowing unambiguous identification of the compounds in a short turnaround time to either confirm…”
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Identification and quantification of 35 psychotropic drugs and metabolites in hair by LC-MS/MS: application in forensic toxicology
Published in International journal of legal medicine (01-03-2015)“…Despite a non-invasive sampling, hair samples are generally collected in limited amounts for an obvious esthetic reason. In order to reduce the required…”
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Self‐poisoning with 60 tablets of Apixaban, a pharmacokinetics case report
Published in British journal of clinical pharmacology (01-01-2019)“…A 67‐year‐old man was admitted to the emergency department about 5 h after deliberate self‐poisoning with 300 mg of Apixaban. The clinical examination did not…”
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Case Report of Ivabradine Intoxication
Published in Journal of analytical toxicology (01-05-2014)“…Ivabradine is a drug used for the treatment of angina and chronic heart failure in cases of intolerance or insufficiency of response to beta-blocker treatment…”
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14
Thyroid function tests in persons with occupational exposure to fipronil
Published in Thyroid (New York, N.Y.) (01-07-2011)“…Fipronil represents a chemical class of insecticides acting at the γ-aminobutyric acid receptor in pests. [corrected] Fipronil has been associated with a…”
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Screening of pesticides in blood with liquid chromatography-linear ion trap mass spectrometry
Published in Analytical and bioanalytical chemistry (01-03-2010)“…In clinical or forensic toxicology, general unknown screening procedures are used to identify as many xenobiotics as possible, belonging to numerous chemical…”
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Improved liquid chromatography-tandem mass spectrometric method for the determination of ethyl glucuronide concentrations in hair: Applications to forensic cases
Published in International journal of legal medicine (2014)“…Ethyl glucuronide (EtG) is a direct marker of ethanol consumption, and its assay in hair is an efficient tool for chronic alcoholism diagnosis. In 2012, the…”
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Analytical Findings of an Acute Intoxication after Inhalation of Methoxetamine
Published in Journal of analytical toxicology (01-09-2014)“…Methoxetamine (MXE) is increasingly used and abused, as it is frequently presented as being safer than ketamine, and legal. Cases of only MXE consumption being…”
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Ethylglucuronide assays in urine and hair
Published in Annales de biologie clinique (Paris) (01-11-2012)“…Ethylglucuronide (EtG) is a biomarker of ethanol consumption, and the authors propose an overview of its potential use in clinical or forensic cases. This…”
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Determination of Dodine in Fruit Samples by Liquid Chromatography Electrospray Ionization-Tandem Mass Spectrometry
Published in Journal of AOAC International (01-01-2011)“…A rapid and sensitive LC/electrospray ionization-MS/MS method has been developed for the determination of dodine in fruit samples. Based on a liquid-liquid…”
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Analyse des herbicides phénoxyacides par chromatographie en phase liquide : 1er essai inter-laboratoires
Published in Annales de toxicologie analytique (2006)“…Afin de documenter au mieux, par des dosages plasmatiques, les cas d'intoxication par les herbicides phénoxyacides, six laboratoires ont évalué diverses…”
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