Search Results - "Dulai, Parambir S"

MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: Clinical trials to clinical practice by Dulai, Parambir S, Sirlin, Claude B, Loomba, Rohit

“…Summary Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of chronic liver disease, and its prevalence is rising worldwide…”
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Natural History of Adult Ulcerative Colitis in Population-based Cohorts: A Systematic Review by Fumery, Mathurin, Singh, Siddharth, Dulai, Parambir S, Gower-Rousseau, Corinne, Peyrin-Biroulet, Laurent, Sandborn, William J

“…Abstract Introduction A comprehensive knowledge of the natural history of UC helps understand disease evolution, identify poor prognostic markers and impact of…”
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Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta‐analysis by Dulai, Parambir S., Singh, Siddharth, Patel, Janki, Soni, Meera, Prokop, Larry J., Younossi, Zobair, Sebastiani, Giada, Ekstedt, Mattias, Hagstrom, Hannes, Nasr, Patrik, Stal, Per, Wong, Vincent Wai‐Sun, Kechagias, Stergios, Hultcrantz, Rolf, Loomba, Rohit

“…Liver fibrosis is the most important predictor of mortality in nonalcoholic fatty liver disease (NAFLD). Quantitative risk of mortality by fibrosis stage has…”
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Population Health Management for Inflammatory Bowel Disease by Dulai, Parambir S., Singh, Siddharth, Ohno-Machado, Lucilla, Sandborn, William J.

“…Inflammatory bowel diseases (IBDs) are chronic and impose significant, multidimensional burdens on patients and health care systems. The increasing prevalence…”
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Progression of Elderly Onset Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Population-Based Cohort Studies by Rozich, Jacob J., Dulai, Parambir S., Fumery, Mathurin, Sandborn, William J., Singh, Siddharth

“…The incidence of inflammatory bowel diseases (IBDs) in older adults is increasing. We performed a systematic review and meta-analysis to evaluate progression…”
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The Real-World Effectiveness and Safety of Vedolizumab for Moderate-Severe Crohn's Disease: Results From the US VICTORY Consortium by Dulai, Parambir S, Singh, Siddharth, Jiang, Xiaoqian, Peerani, Farhad, Narula, Neeraj, Chaudrey, Khadija, Whitehead, Diana, Hudesman, David, Lukin, Dana, Swaminath, Arun, Shmidt, Eugenia, Wang, Shuang, Boland, Brigid S, Chang, John T, Kane, Sunanda, Siegel, Corey A, Loftus, Edward V, Sandborn, William J, Sands, Bruce E, Colombel, Jean-Frederic

“…We assessed the real-world effectiveness and safety of vedolizumab (VDZ) in moderate-severe Crohn's disease (CD). Retrospective cohort study of seven medical…”
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Comparative Efficacy and Rapidity of Action for Infliximab vs Ustekinumab in Biologic Naïve Crohn’s Disease by Narula, Neeraj, Wong, Emily C.L., Dulai, Parambir S., Sengupta, Neil K., Marshall, John K., Colombel, Jean-Frederic, Reinisch, Walter

“…Comparative effectiveness has become increasingly important to help position therapies for inflammatory bowel disease. We compared the efficacy and rapidity of…”
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Assessment of mucosal healing in inflammatory bowel disease: review by Dulai, Parambir S., MBBS, Levesque, Barrett G., MD, MS, Feagan, Brian G., MD, D’Haens, Geert, MD, PhD, Sandborn, William J., MD

“…Background and Aims Mucosal healing is an important treatment end-point in inflammatory bowel disease, and achieving mucosal healing has been demonstrated to…”
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Predictors and outcomes of histological remission in ulcerative colitis treated to endoscopic healing by Jangi, Sushrut, Yoon, Hyuk, Dulai, Parambir S., Valasek, Mark, Boland, Brigid S., Jairath, Vipul, Feagan, Brian G., Sandborn, William J., Singh, Siddharth

“…Summary Background Clinical remission is the recommended treatment target in ulcerative colitis. The predictors and outcomes of achieving histologic remission…”
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Long-Term Outcomes of Early vs Delayed Responders to Vedolizumab and Adalimumab: A Post Hoc Analysis of the VARSITY Study by Narula, Neeraj, Wong, Emily C.L., Marshall, John K., Jairath, Vipul, Dulai, Parambir S., Reinisch, Walter

“…It is uncertain whether patients with ulcerative colitis (UC) and delayed symptomatic response to therapy have as robust and durable a response as earlier…”
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Comparative Efficacy for Infliximab Vs Vedolizumab in Biologic Naive Ulcerative Colitis by Narula, Neeraj, Wong, Emily C.L., Marshall, John K., Colombel, Jean-Frederic, Dulai, Parambir S., Reinisch, Walter

“…Comparative effectiveness studies are needed to help position therapies for ulcerative colitis (UC). We compared the efficacy of infliximab vs vedolizumab for…”
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Rate of, Risk Factors for, and Interventions to Reduce Hospital Readmission in Patients with Inflammatory Bowel Diseases by Nguyen, Nghia H., MD, MAS, Koola, Jejo, MD, Dulai, Parambir S., MD, Prokop, Larry J., MLS, Sandborn, William J., MD, Singh, Siddharth, MD, MS

“…AbstractBackground & AimsWe investigated 30- and 90-day rates and causes of, risk factors for, and interventions to reduce hospital readmission in patients who…”
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Cell Trafficking Interference in Inflammatory Bowel Disease: Therapeutic Interventions Based on Basic Pathogenesis Concepts by Pérez-Jeldres, Tamara, Tyler, Christopher J, Boyer, Joshua D, Karuppuchamy, Thangaraj, Bamias, Giorgos, Dulai, Parambir S, Boland, Brigid S, Sandborn, William J, Patel, Derek R, Rivera-Nieves, Jesús

“…Abstract After 20 years of successful targeting of pro-inflammatory cytokines for the treatment of IBD, an alternative therapeutic strategy has emerged, based…”
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Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa by Ren, Xingsheng, Manzanares, Laura D, Piccolo, Enzo B, Urbanczyk, Jessica M, Sullivan, David P, Yalom, Lenore K, Bui, Triet M, Lantz, Connor, Najem, Hinda, Dulai, Parambir S, Heimberger, Amy B, Thorp, Edward B, Sumagin, Ronen

“…Neutrophil (PMN) mobilization to sites of insult is critical for host defense and requires transendothelial migration (TEM). TEM involves several well-studied…”
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Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial by Dulai, Parambir S, Buckey, Jr, Jay C, Raffals, Laura E, Swoger, Jason M, Claus, Paul L, OʼToole, Kevin, Ptak, Judy A, Gleeson, Michael W, Widjaja, Christella E, Chang, John T, Adler, Jeffery M, Patel, Nihal, Skinner, Laurie A, Haren, Shawn P, Goldby-Reffner, Kimberly, Thompson, Kimberly D, Siegel, Corey A

“…Hyperbaric oxygen therapy (HBOT) markedly increases tissue oxygen delivery. Case series suggest it may have a potential therapeutic benefit in ulcerative…”
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Understanding Determinants of Patient Preferences Between Stool Tests and Colonoscopy for the Assessment of Disease Activity in Inflammatory Bowel Disease by Barsky, Maria, Meserve, Joseph, Le, Helen, Collins, Angelina, Singh, Siddharth, Boland, Brigid, Sandborn, William J., Dulai, Parambir S.

“…Background and Aims Evidence is now available in support of using fecal biomarkers to monitor disease activity in inflammatory bowel disease (IBD). Patient…”
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Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium by Dulai, Parambir S, Bonner, Lauren Balmert, Sadler, Charlotte, Raffals, Laura E, Kochhar, Gursimran, Lindholm, Peter, Buckey, Jr, Jay C, Toups, Gary N, Rosas, Libeth, Narula, Neeraj, Jairath, Vipul, Honap, Sailish, Peyrin-Biroulet, Laurent, Sands, Bruce E, Hanauer, Stephen B, Scholtens, Denise M, Siegel, Corey A

“…Patients with ulcerative colitis (UC) who are hospitalised for acute severe flares represent a high-risk orphan population. To provide guidance for clinical…”
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Correlations Between Gastrointestinal Symptoms and Endoscopic–Histologic Disease Activity in Adults with Ulcerative Colitis by Tse, Chung Sang, Nguyen, Hang P., Singh, Siddharth, Dulai, Parambir S., Neill, Jennifer, Le, Helen, Valasek, Mark, Dervieux, Thierry, Collins, Angelina E., Boland, Brigid Sweeney

“…Introduction Discordance between gastrointestinal (GI) symptoms and endoscopic inflammation in patients with ulcerative colitis (UC) is known. However, the…”
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Location-specific signatures of Crohn's disease at a multi-omics scale by Gonzalez, Carlos G, Mills, Robert H, Zhu, Qiyun, Sauceda, Consuelo, Knight, Rob, Dulai, Parambir S, Gonzalez, David J

“…Crohn's disease (CD), an inflammatory bowel disease (IBD) subtype, results from pathologic interactions between host cells and its resident gut microbes. CD…”
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Systematic review: Safety of balloon assisted enteroscopy in Crohn’s disease by Arulanandan, Ahilan, Dulai, Parambir S, Singh, Siddharth, Sandborn, William J, Kalmaz, Denise

“…AIM To determine the overall and comparative risk of procedure related perforation of balloon assisted enteroscopy(BAE) in Crohn’s disease(CD). METHODS…”
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