Search Results - "Duke, Mary G"
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Analysis of rhodopsin G protein-coupled receptor orthologs reveals semiochemical peptides for parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) interplay
Published in Scientific reports (17-05-2022)“…Schistosomiasis is a medically significant disease caused by helminth parasites of the genus Schistosoma . The schistosome life cycle requires chemically…”
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Identification of Schistosoma mansoni miracidia attractant candidates in infected Biomphalaria glabrata using behaviour-guided comparative proteomics
Published in Frontiers in immunology (10-10-2022)“…Schistosomiasis, caused by infection with Schistosoma digenetic trematodes, is one of the deadliest neglected tropical diseases in the world. The Schistosoma…”
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Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria
Published in The Journal of immunology (1950) (15-09-2010)“…Cerebral malaria is a severe complication of malaria. Sequestration of parasitized RBCs in brain microvasculature is associated with disease pathogenesis, but…”
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Comparative study of excretory-secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata
Published in Parasites & vectors (14-09-2019)“…Schistosomiasis is a harmful neglected tropical disease caused by infection with Schistosoma spp., such as Schistosoma mansoni. Schistosoma must transition…”
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Identification of Putative Neuropeptides That Alter the Behaviour of Schistosoma mansoni Cercariae
Published in Biology (Basel, Switzerland) (12-09-2022)“…Elucidating the infectivity of Schistosoma mansoni, one of the main etiological agents of human schistosomiasis, requires an improved understanding of the…”
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CRISPR/Cas9‐mediated genome editing of Schistosoma mansoni acetylcholinesterase
Published in The FASEB journal (01-01-2021)“…CRISPR/Cas9‐mediated genome editing shows cogent potential for the genetic modification of helminth parasites. We report successful gene knock‐in (KI) into the…”
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Development of CRISPR/Cas13a-based assays for the diagnosis of Schistosomiasis
Published in EBioMedicine (01-08-2023)“…Schistosomiasis is a disease that significantly impacts human health in the developing world. Effective diagnostics are urgently needed for improved control of…”
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ARGONAUTE2 Localizes to Sites of Sporocysts in the Schistosome-Infected Snail, Biomphalaria glabrata
Published in Genes (03-08-2024)“…MicroRNAs (miRNAs) are a class of small regulatory RNA that are generated via core protein machinery. The miRNAs direct gene-silencing mechanisms to mediate an…”
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The insulin receptor is a transmission blocking veterinary vaccine target for zoonotic Schistosoma japonicum
Published in International journal for parasitology (01-08-2012)“…[Display omitted] ► Depressed growth of adult Schistosomajaponicum was observed in rSjLD2-vaccinated mice. ► Significant reduction was observed in the numbers…”
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Development of CRISPR/Cas13a-based assays for the diagnosis of SchistosomiasisResearch in context
Published in EBioMedicine (01-08-2023)“…Background: Schistosomiasis is a disease that significantly impacts human health in the developing world. Effective diagnostics are urgently needed for…”
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