Search Results - "Duivenvoorden, Wilhelmina C"
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Cardiovascular risk in ADT recipients: does the type of ADT matter?
Published in Prostate cancer and prostatic diseases (01-09-2024)Get full text
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Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE−/−:Ins2+/Akita mouse model
Published in Prostate cancer and prostatic diseases (01-06-2021)“…Background Unlike in other mouse models of atherogenesis, it has recently been suggested that orchiectomy plays a role in attenuating atherosclerosis and…”
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Endoplasmic reticulum protein ERp46 in renal cell carcinoma
Published in PloS one (03-03-2014)“…An established inverse clinical correlation between serum adiponectin levels and renal cell carcinoma (RCC) aggressiveness exists. We have recently…”
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Elevated C‐Peptides, Abdominal Obesity, and Abnormal Adipokine Profile are Associated With Higher Gleason Scores in Prostate Cancer
Published in The Prostate (01-02-2017)“…BACKGROUND Prostate cancer development is associated with numerous lifestyle factors (i.e., physical activity, nutrition intake) and metabolic perturbations…”
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Cardiovascular Morbidity in a Randomized Trial Comparing GnRH Agonist and GnRH Antagonist among Patients with Advanced Prostate Cancer and Preexisting Cardiovascular Disease
Published in The Journal of urology (01-12-2019)“…Androgen deprivation therapy may increase the risk of cardiovascular disease. Limited data suggest that GnRH (gonadotropin-releasing hormone) antagonist may be…”
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Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression
Published in Clinical & experimental metastasis (01-02-2014)“…Energy-sensing pathways, normally coordinated by 5′ AMP-activated protein kinase (AMPK), are dysregulated in renal cell carcinoma (RCC). Obesity can accentuate…”
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Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells
Published in Anti-cancer drugs (01-02-2009)“…Commonly used chemotherapeutic agents for breast cancer treatment include cisplatin, doxorubicin, and paclitaxel. Unfortunately, these effective…”
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Low Serum Testosterone in Men with Newly Diagnosed Androgen-Deprivation Therapy-Naïve Prostate Cancer and Its Relationship to Cardiovascular Risk Factors: A RADICAL-PC Substudy
Published in The Journal of urology (01-05-2022)“…Cardiovascular disease is a common cause of death in prostate cancer patients. Low testosterone is associated with increased cardiovascular risk in the general…”
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GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model
Published in Urologic oncology (01-11-2014)“…Abstract Objectives Observational studies relate androgen deprivation therapy (ADT) to metabolic syndrome (MS) and cardiovascular disease, an association…”
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Incidence, Characteristics and Implications of Thromboembolic Events in Patients with Muscle Invasive Urothelial Carcinoma of the Bladder Undergoing Neoadjuvant Chemotherapy
Published in The Journal of urology (01-12-2016)“…Purpose Neoadjuvant chemotherapy and pelvic surgery are significant risk factors for thromboembolic events. Our study objectives were to investigate the…”
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Follicle-Stimulating Hormone Exacerbates Cardiovascular Disease in the Presence of Low or Castrate Testosterone Levels
Published in JACC. Basic to translational science (01-03-2024)“…[Display omitted] •Hypogonadism and PC are common in aging men and associate with cardiovascular disease. ADT to suppress T in PC patients also affects FSH.•We…”
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Does androgen-deprivation therapy for prostate cancer increase the risk for thromboembolic disease?
Published in Canadian Urological Association journal (01-01-2017)Get full text
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Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
Published in Oncology reports (01-10-2015)“…While normal kidneys are relatively sensitive to ionizing radiation (IR), renal cell carcinoma (RCC) is considered radioresistant. Carbonic anhydrase IX (CA9),…”
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Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma
Published in Oncology letters (01-05-2017)“…Endoplasmic reticulum (ER) protein ERp46 is a member of the protein disulfide isomerase family of oxidoreductases, which facilitates the reduction of…”
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Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents
Published in Clinical & experimental metastasis (01-11-2006)“…Numerous cancer patients fail standard chemotherapy or develop resistance to chemotherapy during the course of treatment. The purpose of this study is to…”
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Doxycycline decreases tumor burden in a bone metastasis model of human breast cancer
Published in Cancer research (Chicago, Ill.) (15-03-2002)“…Bone is one of the most frequent sites for metastasis in breast cancer patients,often resulting in significant clinical morbidity and mortality. Increased…”
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Presence and enzymatic activity of prostate-specific antigen in archival prostate cancer samples
Published in Oncology reports (01-10-2008)“…Patients with advanced prostate cancer frequently have a poor prognosis as a result of metastasis. The serum prostate-specific antigen (PSA) test is widely…”
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Divergent effects of orthosilicic acid and dimethylsilanediol on cell survival and adhesion in human osteoblast-like cells
Published in Journal of trace elements in medicine and biology (01-01-2008)“…Although dietary silicon (Si) is recognized to be an important factor for the growth and development of bone and connective tissue, its biochemical role has…”
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