Search Results - "Duits, Lucas"

Barrett's oesophagus patients with low-grade dysplasia can be accurately risk-stratified after histological review by an expert pathology panel by Duits, Lucas C, Phoa, K Nadine, Curvers, Wouter L, Ten Kate, Fiebo J W, Meijer, Gerrit A, Seldenrijk, Cees A, Offerhaus, G Johan, Visser, Mike, Meijer, Sybren L, Krishnadath, Kausilia K, Tijssen, Jan G P, Mallant-Hent, Rosalie C, Bergman, Jacques J G H M

“…Reported malignant progression rates for low-grade dysplasia (LGD) in Barrett's oesophagus (BO) vary widely. Expert histological review of LGD is advised, but…”
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Degree of crypt atypia correlates with progression to high‐grade dysplasia/adenocarcinoma in non‐dysplastic Barrett's oesophagus by Odze, Robert, Frei, Nicola, Khoshiwal, Amir M, Duits, Lucas C, Bergman, Jacques, Stachler, Matthew D

“…Aims Patients with non‐dysplastic Barrett's oesophagus (BE) often show a wide range of ‘atypical’ histological features in the bases of the crypts. However,…”
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Comments on “TSP-9: A Barrett’s Esophagus Biomarker Better Than Pathologists?” by Duits, Lucas C., Critchley-Thorne, Rebecca J., Bergman, Jacques J.G.H.M.

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S386 An Objective Spatialomics Test Standardizes Management Decisions With Potential to Improve Health Outcomes for Barrett’s Esophagus Patients by Frei, Nicola F. F., Duits, Lucas C., Khoshiwal, Amir, Pouw, Roos E., Smolko, Christian, Arora, Meenakshi, Siegel, Jennifer J., Critchley-Thorne, Rebecca, Bergman, Jacques

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An Automated Tissue Systems Pathology Test Can Standardize the Management and Improve Health Outcomes for Patients With Barrett's Esophagus by Duits, Lucas C, Khoshiwal, Amir M, Frei, Nicola F, Pouw, Roos E, Smolko, Christian, Arora, Meenakshi, Siegel, Jennifer J, Critchley-Thorne, Rebecca J, Bergman, Jacques J G H M

“…Low-grade dysplasia (LGD) in Barrett's esophagus (BE) is associated with an increased risk of progression to high-grade dysplasia or esophageal adenocarcinoma…”
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S599 The Tissue Systems Pathology Test Predicts Risk of Progression in Medicare-Eligible Patients with Barrett’s Esophagus by Khara, Harshit S., Davison, Jon M., Goldblum, John, Thota, Prashanthi N., Duits, Lucas C., Khoshiwal, Amir, Bergman, Jacques J., Falk, Gary, Smolko, Christian, Hall, Mary, Siegel, Jennifer J., Critchley-Thorne, Rebecca J., Diehl, David L.

“…Introduction: Accurate prediction of risk of progression to esophageal adenocarcinoma (EAC) is needed in patients with Barrett’s esophagus (BE), which…”
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Patients With Barrett’s Esophagus and Confirmed Persistent Low-Grade Dysplasia Are at Increased Risk for Progression to Neoplasia by Duits, Lucas C, van der Wel, M.J, Cotton, Cary C, Phoa, K. Nadine, ten Kate, Fiebo J.W, Seldenrijk, Cees A, Offerhaus, G. Johan A, Visser, Mike, Meijer, Sybren L, Mallant-Hent, Rosalie C, Krishnadath, Kausilia K, Pouw, Roos E, Tijssen, Jan G.P, Shaheen, Nicholas J, Bergman, Jacques J.G.H.M

“…Background & Aims For patients with Barrett’s esophagus, the diagnosis of low-grade dysplasia (LGD) is subjective, and reported outcomes vary. We analyzed data…”
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A substantial advance for screening of oesophageal cancer by Dawsey, Sanford M, Duits, Lucas C

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The Tissue Systems Pathology Test Outperforms Pathology Review in Risk Stratifying Patients With Low-Grade Dysplasia by Khoshiwal, Amir M., Frei, Nicola F., Pouw, Roos E., Goldblum, John, Montgomery, Elizabeth, Davison, Jon, Singh, Jagjit, Szymanski, Jared, Perry, Anthony, Seldenrijk, Kees, Kate, Fiebo ten, Offerhaus, G. Johan A., Drillenberg, Paul, Jansen, Casper, Leeuwis-Fedorovic, Natalja, Chetty, Runjan, Feakins, Roger, Jansen, Marnix, Chinyama, Catherine, Cooper, Edwin, Vaziri, Reza, Baretton, Gustavo, Tannapfel, Andrea, Vieth, Michael, Melcher, Balint, Mesteri, Ildiko, Müller, Heiko, Wetzel, Philipp, de Hertogh, Gert, Hoorens, Anne, Verschuere, Stepanie, Tamsin, An, Wetzels, Kevin, Caillie, Marie-Astrid van, Smolko, Christian, Arora, Meenakshi, Siegel, Jennifer J., Duits, Lucas C., Critchley-Thorne, Rebecca J., Bergman, Jacques J.G.H.M.

“…Low-grade dysplasia (LGD) is associated with an increased risk of progression in Barrett’s esophagus (BE); however, the diagnosis of LGD is limited by…”
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The use of a real-time computer-aided detection system for visible lesions in the Barrett’s esophagus during live endoscopic procedures: a pilot study (with video) by Fockens, Kiki N., Jukema, Jelmer B., Jong, Martijn R., Boers, Tim, van der Putten, Joost A., Kusters, Carolus H.J., Pouw, Roos E., Duits, Lucas C., van der Sommen, Fons, de With, Peter H., de Groof, A. Jeroen, Bergman, Jacques J., Alkhalaf, Alaa, Herrero, Lorenza Alvarez, Baldaque-Silva, Francisco, Barret, Maximilien, Bergman, Jacques J., Beyna, Torsten, Boers, Tim G., Elbe, Peter, Fockens, Kiki N., de Groof, Albert J., Houben, Martin H., Jong, Martijn, Jukema, Jelmer B., Kusters, Koen C., Mallant-Hent, Rosalie C., Villarejo, Guiomar Moral, Nagengast, Wouter, Fernández-Sordo, Jacobo Ortiz, Pech, Oliver, Pouw, Roos E., van der Putten, Joost A., Ragunath, Krish, Scholten, Pieter, Seewald, Stefan, der Sommen, Fons van, Westerhof, Jessie, Weusten, Bas L., de With, Peter H.

“…This pilot study evaluated the performance of a recently developed computer-aided detection (CADe) system for Barrett’s neoplasia during live endoscopic…”
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Feasibility Study Utilizing NanoString's Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett's Esophagus Formalin-Fixed Paraffin-Embedded Tissues by Qurat-Ul-Ain, Frei, Nicola F, Khoshiwal, Amir M, Stougie, Pim, Odze, Robert, Camilleri-Broet, Sophie, Ferri, Lorenzo, Duits, Lucas C, Bergman, Jacques, Stachler, Matthew D

“…Characterization of the Barrett's esophagus (BE) microenvironment in patients with a known progression status, to determine how it may influence BE progression…”
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A Tissue Systems Pathology Assay for High-Risk Barrett's Esophagus by Critchley-Thorne, Rebecca J, Duits, Lucas C, Prichard, Jeffrey W, Davison, Jon M, Jobe, Blair A, Campbell, Bruce B, Zhang, Yi, Repa, Kathleen A, Reese, Lia M, Li, Jinhong, Diehl, David L, Jhala, Nirag C, Ginsberg, Gregory, DeMarshall, Maureen, Foxwell, Tyler, Zaidi, Ali H, Lansing Taylor, D, Rustgi, Anil K, Bergman, Jacques J G H M, Falk, Gary W

“…Better methods are needed to predict risk of progression for Barrett's esophagus. We aimed to determine whether a tissue systems pathology approach could…”
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A Tissue Systems Pathology Test Detects Abnormalities Associated with Prevalent High-Grade Dysplasia and Esophageal Cancer in Barrett's Esophagus by Critchley-Thorne, Rebecca J, Davison, Jon M, Prichard, Jeffrey W, Reese, Lia M, Zhang, Yi, Repa, Kathleen, Li, Jinhong, Diehl, David L, Jhala, Nirag C, Ginsberg, Gregory G, DeMarshall, Maureen, Foxwell, Tyler, Jobe, Blair A, Zaidi, Ali H, Duits, Lucas C, Bergman, Jacques J G H M, Rustgi, Anil, Falk, Gary W

“…There is a need for improved tools to detect high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. In previous…”
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The Presence of Genetic Mutations at Key Loci Predicts Progression to Esophageal Adenocarcinoma in Barrett's Esophagus by Eluri, Swathi, Brugge, William R, Daglilar, Ebubekir S, Jackson, Sara A, Styn, Mindi A, Callenberg, Keith M, Welch, Derek C, Barr, Todd M, Duits, Lucas C, Bergman, Jacques J, Shaheen, Nicholas J

“…Risk stratification in Barrett's esophagus (BE) is challenging. We evaluated the ability of a panel of genetic markers to predict progression to high-grade…”
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Improved diagnostic stratification of digitised Barrett's oesophagus biopsies by p53 immunohistochemical staining by Wel, Myrtle J, Duits, Lucas C, Pouw, Roos E, Seldenrijk, Cornelis A, Offerhaus, G J A, Visser, Mike, Kate, Fiebo J, Biermann, Katharina, Brosens, Lodewijk A A, Doukas, Michael, Huysentruyt, Clement, Karrenbeld, Arend, Kats‐Ugurlu, Gursah, Laan, Jaap S, Lijnschoten, G (Ineke), Moll, Freek C P, Ooms, Ariadne H A G, Valk, Hans, Tijssen, Jan G, Bergman, Jacques J, Meijer, Sybren L

“…Aims Interobserver agreement for dysplasia in Barrett's oesophagus (BO) is low, and guidelines advise expert review of dysplastic cases. The aim of this study…”
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A Tissue Systems Pathology Test Outperforms the Standard-of-Care Variables in Predicting Progression in Patients With Barrett's Esophagus by Davison, Jon M, Goldblum, John R, Duits, Lucas C, Khoshiwal, Amir M, Bergman, Jacques J, Falk, Gary W, Diehl, David L, Khara, Harshit S, Smolko, Christian, Arora, Meenakshi, Siegel, Jennifer J, Critchley-Thorne, Rebecca J, Thota, Prashanthi N

“…Objective risk stratification is needed for patients with Barrett's esophagus (BE) to enable risk-aligned management to improve health outcomes. This study…”
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Spatial predisposition of dysplasia in Barrett's esophagus segments: a pooled analysis of the SURF and AIM dysplasia trials by Cotton, Cary C, Duits, Lucas C, Wolf, W Asher, Peery, Anne F, Dellon, Evan S, Bergman, Jacques J, Shaheen, Nicholas J

“…Surveillance endoscopy detects dysplasia within Barrett's esophagus (BE) and dictates treatment. Current biopsy regimens recommend uniformly spaced random…”
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Barrett's esophagus surveillance in a prospective Dutch multi‐center community‐based cohort of 985 patients demonstrates low risk of neoplastic progression by Klaver, Esther, Bureo Gonzalez, Angela, Mostafavi, Nahid, Mallant‐Hent, Rosalie, Duits, Lucas C., Baak, Bert, Böhmer, Clarisse J. M., Oijen, Arnoud H. A. M., Naber, Ton, Scholten, Pieter, Meijer, Sybren L., Bergman, Jacques J. G. H. M., Pouw, Roos E.

“…Background and Aims Barrett's esophagus (BE) is accompanied by an increased risk of developing esophageal cancer. Accurate risk‐stratification is warranted to…”
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Sa1924 Utility of a Biomarker Panel to Predict Progression to Esophageal Adenocarcinoma in Barrett's Esophagus by Wolf, W. Asher, Lao-Sirieix, Pierre, Duits, Lucas C, Chak, Amitabh, Shaheen, Nicholas J, Fitzgerald, Rebecca, Bergman, Jacques J

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Tu1532 Is There a Spatial Predisposition to Dysplasia in a Barrett's Esophagus Segment? a Combined Analysis of the Surf and AIM - Dysplasia Trials by Cotton, Cary C, Duits, Lucas C, Wolf, W. Asher, Peery, Anne F, Dellon, Evan S, Bergman, Jacques J, Shaheen, Nicholas J

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