Search Results - "Duina, Andrea"
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Budding yeast for budding geneticists: a primer on the Saccharomyces cerevisiae model system
Published in Genetics (Austin) (01-05-2014)“…The budding yeast Saccharomyces cerevisiae is a powerful model organism for studying fundamental aspects of eukaryotic cell biology. This Primer article…”
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Dominant effects of the histone mutant H3-L61R on Spt16-gene interactions in budding yeast
Published in Epigenetics (01-12-2022)“…Recent studies have unveiled an association between an L61R substitution within the human histone H3.3 protein and the presentation of neurodevelopmental…”
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Assessing contributions of DNA sequences at the 3' end of a yeast gene on yFACT, RNA polymerase II, and nucleosome occupancy
Published in BMC research notes (06-08-2024)“…In past work in budding yeast, we identified a nucleosomal region required for proper interactions between the histone chaperone complex yFACT and transcribed…”
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New roles for old characters: an educational primer for use with "Vps factors are required for efficient transcription elongation in budding yeast"
Published in Genetics (Austin) (01-05-2013)“…An article from Alan Hinnebusch's laboratory in the March 2013 issue of GENETICS establishes an exciting new link between proteins with well-established roles…”
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Charged residues on the side of the nucleosome contribute to normal Spt16-gene interactions in budding yeast
Published in Epigenetics (01-01-2018)“…Previous work in Saccharomyces cerevisiae identified three residues located in close proximity to each other on the side of the nucleosome whose integrity is…”
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Mutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3
Published in PloS one (06-06-2011)“…In eukaryotic cells, the highly conserved FACT (FAcilitates Chromatin Transcription) complex plays important roles in several chromatin-based processes…”
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Targeted in Situ Mutagenesis of Histone Genes in Budding Yeast
Published in Journal of visualized experiments (26-01-2017)“…We describe a PCR- and homologous recombination-based system for generating targeted mutations in histone genes in budding yeast cells. The resulting mutant…”
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Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed Genes
Published in Genetics Research International (01-01-2011)“…The process of gene transcription requires the participation of a large number of factors that collectively promote the accurate and efficient expression of an…”
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Evidence that dissociation of Spt16 from transcribed genes is partially dependent on RNA Polymerase II termination
Published in Transcription (20-10-2019)“…FACT (FAcilitates Chromatin Transactions) is a highly conserved histone chaperone complex in eukaryotic cells that can interact and manipulate nucleosomes in…”
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Evidence that the localization of the elongation factor Spt16 across transcribed genes is dependent upon histone H3 integrity in Saccharomyces cerevisiae
Published in Genetics (Austin) (01-09-2007)“…A previous study of histone H3 in Saccharomyces cerevisiae identified a mutant with a single amino acid change, leucine 61 to tryptophan, that confers several…”
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Analysis of a Mutant Histone H3 That Perturbs the Association of Swi/Snf with Chromatin
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A nucleosomal region important for ensuring proper interactions between the transcription elongation factor Spt16 and transcribed genes in Saccharomyces cerevisiae
Published in G3 : genes - genomes - genetics (01-06-2013)“…The highly conserved FACT (FAcilitates Chromatin Transactions) histone chaperone assists in the transcription elongation process first by facilitating the…”
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A systematic mutational analysis of a histone H3 residue in budding yeast provides insights into chromatin dynamics
Published in G3 : genes - genomes - genetics (23-02-2015)“…In previous work using the Saccharomyces cerevisiae model system, a mutant version of histone H3-H3-L61W-was found to confer a variety of abnormal growth…”
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Uncoupling of the Patterns of Chromatin Association of Different Transcription Elongation Factors by a Histone H3 Mutant in Saccharomyces cerevisiae
Published in Eukaryotic Cell (01-02-2009)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Cyclophilin Function in Hsp90-Dependent Signal Transduction
Published in Science (American Association for the Advancement of Science) (06-12-1996)“…Cpr6 and Cpr7, the Saccharomyces cerevisiae homologs of cyclophilin-40 (CyP-40), were shown to form complexes with Hsp90, a protein chaperone that functions in…”
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Requirement for Hsp90 and a CyP-40-type Cyclophilin in Negative Regulation of the Heat Shock Response
Published in The Journal of biological chemistry (24-07-1998)“…The heat shock response is a highly conserved mechanism that allows cells to withstand a variety of stress conditions. Activation of this response is…”
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Identification of two CyP‐40‐like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth
Published in Yeast (Chichester, England) (01-08-1996)“…We report the analysis of two Saccharomyces cerevisiae cyclophilins, Cpr6 and Cpr7, identified by their ability to interact in vivo with the transcriptional…”
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Targeted in Situ Mutagenesis of Histone Genes in Budding Yeast
Published in Journal of visualized experiments (26-01-2017)Get full text
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Trapping of yFACT at 3' ends of genes is not a universal characteristic of yeast versions of Bryant-Li-Bhoj syndrome histone H3 mutants
Published in microPublication biology (01-01-2024)“…Bryant-Li-Bhoj syndrome (BLBS) is associated with germline mutations in the genes encoding human histone H3.3. While to date 70 H3.3 mutants have been…”
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The Peptidyl-prolyl Isomerase Domain of the CyP-40 Cyclophilin Homolog Cpr7 Is Not Required to Support Growth or Glucocorticoid Receptor Activity in Saccharomyces cerevisiae
Published in The Journal of biological chemistry (01-05-1998)“…CyP-40 cyclophilins are found in association with molecular chaperone Hsp90·steroid receptor complexes. The amino-terminal portion of these cyclophilins…”
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