Experimental Study of the Efficiency of Impaza on the Model of Chronic Aseptic Prostatic Inflammation

We compared the efficacy of Impaza (antibodies against endothelial NO-synthase in ultra-low doses) and Serenoa repens on the rat model of chronic aseptic prostatic inflammation. Administration of Serenoa repens in a dose of 50 mg/kg for 1.5 months prevented the development of prostate sclerosis and...

Full description

Saved in:

Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 154; no. 2; pp. 217 - 219
Main Authors:	Borovskaya, T. G., Fomina, T. I., Pakhomova, A. V., Ermolaeva, L. A., Poluektova, M. E., Zhavbert, E. S., Dugina, Ju. L., Kheifets, I. A., Epstein, O. I.
Format:	Journal Article
Language:	English
Published:	Boston Springer US 01-12-2012 Springer Springer Nature B.V
Subjects:	Animals Antibodies - therapeutic use Biomedical and Life Sciences Biomedicine Cell Biology Erectile Dysfunction Inflammation Internal Medicine Laboratory Medicine Male Nitric Oxide Synthase Type III - metabolism Pathology Pharmacology and Toxicology Plant Extracts - therapeutic use Prostatitis - drug therapy Prostatitis - metabolism Rats Serenoa - chemistry Serenoa repens Sexual disorders chronic prostatitis ultra-low doses of antibodies against endothelial NO-synthase erectile dysfunction
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	We compared the efficacy of Impaza (antibodies against endothelial NO-synthase in ultra-low doses) and Serenoa repens on the rat model of chronic aseptic prostatic inflammation. Administration of Serenoa repens in a dose of 50 mg/kg for 1.5 months prevented the development of prostate sclerosis and increased luminal area, but did delay the development of atrophic processes. In animals treated with Impaza (3 ml/kg for 1.5 months), atrophic changes in the prostate gland were practically absent. These findings indicate that Impaza can be used in complex therapy of abacterial prostatitis.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-012-1916-0