Search Results - "Dugave, C"
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Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response
Published in Mucosal immunology (01-03-2014)“…In celiac disease, enhanced permeability to gliadin peptides can result from their apico-basal transport by secretory immunoglobulin A1 (SIgA1) binding to the…”
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Iron‐free pyoverdin binds to its outer membrane receptor FpvA in Pseudomonas aeruginosa: a new mechanism for membrane iron transport
Published in Molecular microbiology (01-01-2001)“…Under iron limitation, Pseudomonas aeruginosa secretes a fluorescent siderophore called pyoverdin, which, after complexing iron, is transported back into the…”
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The Structure−Activity Relationship of Ferric Pyoverdine Bound to Its Outer Membrane Transporter: Implications for the Mechanism of Iron Uptake
Published in Biochemistry (Easton) (01-11-2005)“…Under iron limitation, Pseudomonas aeruginosa ATCC 15692 secretes a major siderophore, pyoverdine I (PvdI). This molecule chelates iron in the extracellular…”
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Cis−Trans Isomerization of Organic Molecules and Biomolecules: Implications and Applications
Published in Chemical reviews (01-07-2003)“…The purpose of the present review is not to list all isomerization processes described in the literature but to provide a comprehensive overview of the…”
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Regioselective and Stereospecific Deuteration of Bioactive Aza Compounds by the Use of Ruthenium Nanoparticles
Published in Angewandte Chemie International Edition (03-01-2014)“…An efficient H/D exchange method allowing the deuteration of pyridines, quinolines, indoles, and alkyl amines with D2 in the presence of Ru@PVP nanoparticles…”
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Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling
Published in Journal of organic chemistry (20-12-2019)“…A visible-light-mediated late-stage aminocarbonylation of unactivated alkyl iodides with stoichiometric amounts of carbon monoxide is presented. The method…”
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Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis
Published in Proceedings of the National Academy of Sciences - PNAS (05-05-2009)“…The gene encoding the cytochrome P450 CYP121 is essential for Mycobacterium tuberculosis. However, the CYP121 catalytic activity remains unknown. Here, we show…”
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Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease
Published in The Journal of experimental medicine (21-01-2008)“…Celiac disease (CD) is an enteropathy resulting from an abnormal immune response to gluten-derived peptides in genetically susceptible individuals. This immune…”
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Isotopic Radiolabeling of Crizotinib with Fluorine-18 for In Vivo Pet Imaging
Published in Pharmaceuticals (Basel, Switzerland) (01-12-2022)“…Crizotinib is a tyrosine kinase inhibitor approved for the treatment of non-small-cell lung cancer, but it is inefficient on brain metastases. Crizotinib is a…”
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Alterations of the intestinal transport and processing of gliadin peptides in celiac disease
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2003)“…Background & aims : The hypothesis of a defect in the intestinal transport and processing of toxic (31–49) or immunostimulant (57–68 and the 33-mer 56–89)…”
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Limited Efficiency of Prolyl-Endopeptidase in the Detoxification of Gliadin Peptides in Celiac Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2005)“…Background & Aims: The resistance of prolamines to digestive enzymes is thought to be a key contributor to the pathogenesis of celiac disease by promoting the…”
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The Synthetic Peptide Trp-Lys-Tyr-Met-Val-Met-NH2 Specifically Activates Neutrophils through FPRL1/Lipoxin A4 Receptors and Is an Agonist for the Orphan Monocyte-expressed Chemoattractant Receptor FPRL2
Published in The Journal of biological chemistry (15-06-2001)“…Neutrophils express the G protein-coupled N-formyl peptide receptor (FPR) and its homologue FPRL1, whereas monocytes express FPR, FPRL1, and FPRL2, an orphan…”
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Intestinal absorption of miltefosine : Contribution of passive paracellular transport
Published in Pharmaceutical research (01-03-2007)“…This study aimed to characterize the transepithelial transport of miltefosine (HePC), the first orally effective drug against visceral leishmaniasis, across…”
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Sialorphin, a Natural Inhibitor of Rat Membrane-Bound Neutral Endopeptidase That Displays Analgesic Activity
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2003)“…Sialorphin is an exocrine and endocrine signaling mediator, which has been identified by a genomic approach. It is synthesized predominantly in the…”
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Synthesis and Evaluation of Glyψ(PO2R-N)Pro-Containing Pseudopeptides as Novel Inhibitors of the Human Cyclophilin hCyp-18
Published in Journal of medicinal chemistry (29-08-2002)“…The human cyclophilin hCyp-18, an abundant peptidyl-prolyl cis−trans isomerase (PPIase) implicated in protein folding, controls the infection of CD4+ T-cells…”
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