Search Results - "Dugas, M."

Benchmarking atlas-level data integration in single-cell genomics by Luecken, Malte D., Büttner, M., Chaichoompu, K., Danese, A., Interlandi, M., Mueller, M. F., Strobl, D. C., Zappia, L., Dugas, M., Colomé-Tatché, M., Theis, Fabian J.

“…Single-cell atlases often include samples that span locations, laboratories and conditions, leading to complex, nested batch effects in data. Thus, joint…”
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Evaluation of technical approaches for real-time data transfer from electronic health record systems by Kirilov, N., Dugas, M.

“…•Real-time data are data received immediately after creation and their key feature is low latency.•Fast Health Interoperability Resources is a widely used…”
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Electronic health records: new opportunities for clinical research by Coorevits, P., Sundgren, M., Klein, G. O., Bahr, A., Claerhout, B., Daniel, C., Dugas, M., Dupont, D., Schmidt, A., Singleton, P., De Moor, G., Kalra, D.

“…Clinical research is on the threshold of a new era in which electronic health records (EHRs) are gaining an important novel supporting role. Whilst EHRs used…”
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Canagliflozin Prevents Intrarenal Angiotensinogen Augmentation and Mitigates Kidney Injury and Hypertension in Mouse Model of Type 2 Diabetes Mellitus by Woods, T Cooper, Satou, Ryousuke, Miyata, Kayoko, Katsurada, Akemi, Dugas, Courtney M, Klingenberg, Natasha C, Fonseca, Vivian A, Navar, L Gabriel

“…Hypertension and renal injury are common complications of type 2 diabetes mellitus (T2DM). Hyperglycemia stimulates renal proximal tubular angiotensinogen…”
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The intolerance of uncertainty scale: psychometric properties of the English version by Buhr, K, Dugas, M.J

“…Research is now suggesting that intolerance of uncertainty may be very important in understanding worry and may play a key role in the etiology and maintenance…”
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Landscape of genetic lesions in 944 patients with myelodysplastic syndromes by Haferlach, T, Nagata, Y, Grossmann, V, Okuno, Y, Bacher, U, Nagae, G, Schnittger, S, Sanada, M, Kon, A, Alpermann, T, Yoshida, K, Roller, A, Nadarajah, N, Shiraishi, Y, Shiozawa, Y, Chiba, K, Tanaka, H, Koeffler, H P, Klein, H-U, Dugas, M, Aburatani, H, Kohlmann, A, Miyano, S, Haferlach, C, Kern, W, Ogawa, S

“…High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic syndromes (MDS). We determined the…”
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Blockade of sodium-glucose cotransporter 2 suppresses high glucose-induced angiotensinogen augmentation in renal proximal tubular cells by Satou, Ryousuke, Cypress, Michael W, Woods, T Cooper, Katsurada, Akemi, Dugas, Courtney M, Fonseca, Vivian A, Navar, L Gabriel

“…Renal proximal tubular angiotensinogen (AGT) is increased by hyperglycemia (HG) in diabetes mellitus, which augments intrarenal angiotensin II formation,…”
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Demonstration of a Multi‐Layer, Lithographically Manufactured Plasma Spectrometer by Scime, E. E., Dugas, M., Gilbert, T. J., John, R., Keesee, A. M., Wagner, G.

“…Development of new plasma instruments is needed to enable constellation‐ and small satellite‐based missions. Key steps in the development pathway of…”
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European academy of dermatology and venereology European prurigo project: expert consensus on the definition, classification and terminology of chronic prurigo by Pereira, M.P., Steinke, S., Zeidler, C., Forner, C., Riepe, C., Augustin, M., Bobko, S., Dalgard, F., Elberling, J., Garcovich, S., Gieler, U., Gonçalo, M., Halvorsen, J. A., Leslie, T.A., Metz, M., Reich, A., Şavk, E., Schneider, G., Serra‐Baldrich, E., Ständer, H.F., Streit, M., Wallengren, J., Weller, K., Wollenberg, A., Bruland, P., Soto‐Rey, I., Storck, M., Dugas, M., Weisshaar, E., Szepietowski, J.C., Legat, F.J., Ständer, S.

“…Background The term prurigo has been used for many decades in dermatology without clear definition, and currently used terminology of prurigo is inconsistent…”
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Immunosuppression by Mycophenolate Mofetil Mitigates Intrarenal Angiotensinogen Augmentation in Angiotensin II-Dependent Hypertension by Satou, Ryousuke, Franco, Martha, Dugas, Courtney M., Katsurada, Akemi, Navar, L. Gabriel

“…Augmentation of intrarenal angiotensinogen (AGT) leads to further formation of intrarenal angiotensin II (Ang II) and the development of hypertensive kidney…”
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The Kitt Peak Electron Multiplying CCD demonstrator by Coughlin, Michael W, Dekany, Richard G, Duev, Dmitry A, Feeney, Michael, Kulkarni, S R, Riddle, Reed, Ahumada, Tomás, Burdge, Kevin, Dugas, Alison M, Fremling, Christoffer U, Hallinan, Gregg, Prince, Thomas A, van Roestel, Jan

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Cross‐European validation of the ItchyQoL in pruritic dermatoses by Zeidler, C., Steinke, S., Riepe, C., Bruland, P., Soto‐Rey, I., Storck, M., Garcovich, S., Blome, C., Bobko, S., Legat, F.J., Potekaev, N., Lvov, A., Misery, L., Weger, W., Reich, A., Şavk, E., Streit, M., Serra‐Baldrich, E., Szepietowski, J.C., Yosipovitch, G., Chen, S.C., Dugas, M., Ständer, S.

“…Background Chronic pruritus (CP) is a frequently occurring symptom in inflammatory dermatoses, causing a high burden and limitations to health‐related quality…”
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The burden in chronic prurigo: patients with chronic prurigo suffer more than patients with chronic pruritus on non-lesional skin: A comparative, retrospective, explorative statistical analysis of 4,484 patients in a real-world cohort by Zeidler, C, Pereira, M P, Dugas, M, Augustin, M, Storck, M, Weyer-Elberich, V, Schneider, G, Ständer, S

“…Chronic prurigo (CPG) is known as a high burdensome disease characterized by severe pruritus and multiple pruriginous lesions. Interestingly, the…”
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Missing semantic annotation in databases. The root cause for data integration and migration problems in information systems by Dugas, M

“…Data integration is a well-known grand challenge in information systems. It is highly relevant in medicine because of the multitude of patient data sources…”
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Tadpole begging reveals high quality by Dugas, M. B., Strickler, S. A., Stynoski, J. L.

“…Parents can benefit from allocating limited resources nonrandomly among offspring, and offspring solicitation (i.e. begging) is often hypothesized to evolve…”
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Chronic nodular prurigo: clinical profile and burden. A European cross‐sectional study by Pereira, M.P., Hoffmann, V., Weisshaar, E., Wallengren, J., Halvorsen, J.A., Garcovich, S., Misery, L., Brenaut, E., Savk, E., Potekaev, N., Lvov, A., Bobko, S., Szepietowski, J.C., Reich, A., Bozek, A., Legat, F.J., Metz, M., Streit, M., Serra‐Baldrich, E., Gonçalo, M., Storck, M., Greiwe, I., Nau, T., Steinke, S., Dugas, M., Ständer, S., Zeidler, C., Dalgard, F., Elberling, J., Forner, C., Leslie, T., Riepe, C., Schneider, G., Ständer, H.

“…Background Chronic nodular prurigo (CNPG) is a condition characterized by chronic itch, a prolonged scratching behaviour and the presence of pruriginous…”
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Frequency analysis of medical concepts in clinical trials and their coverage in MeSH and SNOMED-CT by Varghese, J, Dugas, M

“…Eligibility criteria (EC) of clinical trials play a key role in selecting appropriate study candidates and the validity of the outcome of a clinical trial…”
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Male–male aggression is unlikely to stabilize a poison frog polymorphism by Yang, Y., Dugas, M. B., Sudekum, H. J., Murphy, S. N., Richards‐Zawacki, C. L.

“…Phenotypic polymorphism is common in animals, and the maintenance of multiple phenotypes in a population requires forces that act against homogenizing drift…”
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Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men by Sansone, A., Kliesch, S., Dugas, M., Sandhowe-Klaverkamp, R., Isidori, A. M., Schlatt, S., Zitzmann, M.

“…Purpose Symptoms of hypogonadism are often reported by subjects with normal serum testosterone (T) levels. We aimed to assess the association between clinical…”
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Chronic pruritus: evaluation of patient needs and treatment goals with a special regard to differences according to pruritus classification and sex by Steinke, S., Bruland, P., Blome, C., Osada, N., Dugas, M., Fritz, F., Augustin, M., Ständer, S.

“…Summary Background Chronic pruritus (CP) is present in approximately one‐third of all dermatological patients. Diagnostics and treatment are challenging and…”
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