Search Results - "Dufraing, Kelly"

Molecular pathology testing for non-small cell lung cancer: an observational study of elements currently present in request forms and result reports and the opinion of different stakeholders by Dufraing, Kelly, Van Casteren, Kaat, Breyne, Joke, D'Haene, Nicky, Van Campenhout, Claude, Vander Borght, Sara, Zwaenepoel, Karen, Rouleau, Etienne, Schuuring, Ed, von der Thüsen, Jan, Dequeker, Elisabeth

“…Background For patients with non-small cell lung cancer (NSCLC), targeted therapies are becoming part of the standard treatment. It is of question which…”
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Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples by Keppens, Cleo, Dequeker, Elisabeth M C, Rouleau, Etienne, 't Hart, Nils, Bubendorf, Lukas, Dufraing, Kelly, Garrec, Céline, Guéguen, Paul, Lamy, Aude, Marchetti, Antonio, Pauwels, Patrick, Ryska, Ales, Tack, Véronique, Tornillo, Luigi, Van Casteren, Kaat, von der Thüsen, Jan H, Zwaenepoel, Karen, Lissenberg-Witte, Birgit, Thunnissen, Erik, Schuuring, Ed

“…Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI…”
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External quality assessment for molecular diagnostic laboratories in Belgium: Can we improve it? by Dufraing, Kelly, Lierman, Els, Vankeerberghen, Anne, Franke, Sabine, Dequeker, Els

“…External quality assessment (EQA) is an essential part of performance monitoring for molecular laboratories. At the moment, a national law regulates…”
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Variation in nomenclature of somatic variants for selection of oncological therapies: Can we reach a consensus soon? by Keppens, Cleo, Tack, Véronique, Dufraing, Kelly, Rouleau, Etienne, Ligtenberg, Marjolijn J. L., Schuuring, Ed, Dequeker, Elisabeth M. C.

“…A standardized nomenclature for reporting oncology biomarker variants is key to avoid misinterpretation of results and unambiguous registration in clinical…”
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Neoplastic cell percentage estimation in tissue samples for molecular oncology: recommendations from a modified Delphi study by Dufraing, Kelly, Krieken, J Henricus, De Hertogh, Gert, Hoefler, Gerald, Oniscu, Anca, Kuhlmann, Tine P, Weichert, Wilko, Marchiò, Caterina, Ristimäki, Ari, Ryška, Aleš, Scoazec, Jean‐Yves, Dequeker, Elisabeth

“…Aims Results from external quality assessment revealed considerable variation in neoplastic cell percentages (NCP) estimation in samples for biomarker testing…”
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European follow-up of incorrect biomarker results for colorectal cancer demonstrates the importance of quality improvement projects by Keppens, Cleo, Dufraing, Kelly, van Krieken, Han J., Siebers, Albert G., Kafatos, George, Lowe, Kimberly, Demonty, Gaston, Dequeker, Elisabeth M. C.

“…Biomarker analysis for colorectal cancer has been shown to be reliable in Europe with 97% of samples tested by EQA participants to be correctly classified…”
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The ins and outs of molecular pathology reporting by Tack, Véronique, Dufraing, Kelly, Deans, Zandra C., van Krieken, Han J., Dequeker, Elisabeth M. C.

“…The raid evolution in molecular pathology resulting in an increasing complexity requires careful reporting. The need for standardisation is clearer than ever…”
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Sensitive detection methods are key to identify secondary EGFR c.2369CT p.(Thr790Met) in non-small cell lung cancer tissue samples by Keppens, Cleo, Dequeker, Elisabeth M. C, Rouleau, Etienne, t Hart, Nils, Bubendorf, Lukas, Dufraing, Kelly, Garrec, Céline, Guéguen, Paul, Lamy, Aude, Marchetti, Antonio, Pauwels, Patrick, Ryska, Ales, Tack, Véronique, Tornillo, Luigi, Van Casteren, Kaat, von der Thüsen, Jan H, Zwaenepoel, Karen, Lissenberg-Witte, Birgit, Thunnissen, Erik, Schuuring, Ed

“…Background Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired…”
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External Quality Assessment Identifies Training Needs to Determine the Neoplastic Cell Content for Biomarker Testing by Dufraing, Kelly, De Hertogh, Gert, Tack, Véronique, Keppens, Cleo, Dequeker, Elisabeth M.C., van Krieken, J. Han

“…Neoplastic cell content determination is crucial for biomarker testing. It is known that interobserver variation exists, but largescale data are missing about…”
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