Search Results - "Dufour, Jean‐Francois"

Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests by Masoodi, Mojgan, Gastaldelli, Amalia, Hyötyläinen, Tuulia, Arretxe, Enara, Alonso, Cristina, Gaggini, Melania, Brosnan, Julia, Anstee, Quentin M., Millet, Oscar, Ortiz, Pablo, Mato, Jose M., Dufour, Jean-Francois, Orešič, Matej

“…Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide and is often associated with aspects of metabolic syndrome. Despite…”
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Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis by McPherson, Stuart, Hardy, Tim, Dufour, Jean-Francois, Petta, Salvatore, Romero-Gomez, Manuel, Allison, Mike, Oliveira, Claudia P, Francque, Sven, Van Gaal, Luc, Schattenberg, Jörn M, Tiniakos, Dina, Burt, Alastair, Bugianesi, Elisabetta, Ratziu, Vlad, Day, Christopher P, Anstee, Quentin M

“…Non-invasive fibrosis scores are widely used to identify/exclude advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). However, these…”
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Genetic Variation in HSD17B13 Reduces the Risk of Developing Cirrhosis and Hepatocellular Carcinoma in Alcohol Misusers by Stickel, Felix, Lutz, Philipp, Buch, Stephan, Nischalke, Hans Dieter, Silva, Ines, Rausch, Vanessa, Fischer, Janett, Weiss, Karl Heinz, Gotthardt, Daniel, Rosendahl, Jonas, Marot, Astrid, Elamly, Mona, Krawczyk, Marcin, Casper, Markus, Lammert, Frank, Buckley, Thomas W. M., McQuillin, Andrew, Spengler, Ulrich, Eyer, Florian, Vogel, Arndt, Marhenke, Silke, Felden, Johann, Wege, Henning, Sharma, Rohini, Atkinson, Stephen, Franke, Andre, Nehring, Sophie, Moser, Vincent, Schafmayer, Clemens, Spahr, Laurent, Lackner, Carolin, Stauber, Rudolf E., Canbay, Ali, Link, Alexander, Valenti, Luca, Grove, Jane I., Aithal, Guruprasad P., Marquardt, Jens U., Fateen, Waleed, Zopf, Steffen, Dufour, Jean‐Francois, Trebicka, Jonel, Datz, Christian, Deltenre, Pierre, Mueller, Sebastian, Berg, Thomas, Hampe, Jochen, Morgan, Marsha Y.

“…Background and Aims Carriage of rs738409:G in patatin‐like phospholipase domain containing 3 (PNPLA3) is associated with an increased risk for developing…”
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Prognosis of patients with hepatocellular carcinoma treated with immunotherapy – development and validation of the CRAFITY score by Scheiner, Bernhard, Pomej, Katharina, Kirstein, Martha M., Hucke, Florian, Finkelmeier, Fabian, Waidmann, Oliver, Himmelsbach, Vera, Schulze, Kornelius, von Felden, Johann, Fründt, Thorben W., Stadler, Marc, Heinzl, Harald, Shmanko, Kateryna, Spahn, Stephan, Radu, Pompilia, Siebenhüner, Alexander R., Mertens, Joachim C., Rahbari, Nuh N., Kütting, Fabian, Waldschmidt, Dirk-Thomas, Ebert, Matthias P., Teufel, Andreas, De Dosso, Sara, Pinato, David J., Pressiani, Tiziana, Meischl, Tobias, Balcar, Lorenz, Müller, Christian, Mandorfer, Mattias, Reiberger, Thomas, Trauner, Michael, Personeni, Nicola, Rimassa, Lorenza, Bitzer, Michael, Trojan, Jörg, Weinmann, Arndt, Wege, Henning, Dufour, Jean-François, Peck-Radosavljevic, Markus, Vogel, Arndt, Pinter, Matthias

“…Immunotherapy with atezolizumab plus bevacizumab represents the new standard of care in systemic front-line treatment of hepatocellular carcinoma (HCC)…”
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Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis by Pinyol, Roser, Torrecilla, Sara, Wang, Huan, Montironi, Carla, Piqué-Gili, Marta, Torres-Martin, Miguel, Wei-Qiang, Leow, Willoughby, Catherine E., Ramadori, Pierluigi, Andreu-Oller, Carmen, Taik, Patricia, Lee, Youngmin A., Moeini, Agrin, Peix, Judit, Faure-Dupuy, Suzanne, Riedl, Tobias, Schuehle, Svenja, Oliveira, Claudia P., Alves, Venancio A., Boffetta, Paolo, Lachenmayer, Anja, Roessler, Stephanie, Minguez, Beatriz, Schirmacher, Peter, Dufour, Jean-François, Thung, Swan N., Reeves, Helen L., Carrilho, Flair J., Chang, Charissa, Uzilov, Andrew V., Heikenwalder, Mathias, Sanyal, Arun, Friedman, Scott L., Sia, Daniela, Llovet, Josep M.

“…Non-alcoholic steatohepatitis (NASH)-related hepatocellular carcinoma (HCC) is increasing globally, but its molecular features are not well defined. We aimed…”
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Stress-activated miR-21/miR-21 in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption by Calo, Nicolas, Ramadori, Pierluigi, Sobolewski, Cyril, Romero, Yannick, Maeder, Christine, Fournier, Margot, Rantakari, Pia, Zhang, Fu-Ping, Poutanen, Matti, Dufour, Jean-François, Humar, Bostjan, Nef, Serge, Foti, Michelangelo

“…is an oncomir highly upregulated in hepatocellular carcinoma and in early stages of liver diseases characterised by the presence of steatosis. Whether…”
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Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis by Sanyal, Arun J., Ratziu, Vlad, Loomba, Rohit, Anstee, Quentin M., Kowdley, Kris V., Rinella, Mary E., Sheikh, Muhammad Y., Trotter, James F., Knapple, Whitfield, Lawitz, Eric J., Abdelmalek, Manal F., Newsome, Philip N., Boursier, Jérôme, Mathurin, Philippe, Dufour, Jean-François, Berrey, M. Michelle, Shiff, Steven J., Sawhney, Sangeeta, Capozza, Thomas, Leyva, Rina, Harrison, Stephen A., Younossi, Zobair M.

“…Obeticholic acid (OCA) is a first-in-class farnesoid X receptor agonist and antifibrotic agent in development for the treatment of pre-cirrhotic liver fibrosis…”
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COVID-19 in an international European liver transplant recipient cohort by Becchetti, Chiara, Zambelli, Marco Fabrizio, Pasulo, Luisa, Donato, Maria Francesca, Invernizzi, Federica, Detry, Olivier, Dahlqvist, Géraldine, Ciccarelli, Olga, Morelli, Maria Cristina, Fraga, Montserrat, Svegliati-Baroni, Gianluca, van Vlierberghe, Hans, Coenraad, Minneke J, Romero, Mario Cristobal, de Gottardi, Andrea, Toniutto, Pierluigi, Del Prete, Luca, Abbati, Claudia, Samuel, Didier, Pirenne, Jacques, Nevens, Frederik, Dufour, Jean-François

“…Knowledge on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in liver transplant recipients is lacking, particularly in terms of…”
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IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes by Bochud, Pierre-Yves, Bibert, Stéphanie, Kutalik, Zoltán, Patin, Etienne, Guergnon, Julien, Nalpas, Bertrand, Goossens, Nicolas, Kuske, Lorenz, Müllhaupt, Beat, Gerlach, Tillman, Heim, Markus H., Moradpour, Darius, Cerny, Andreas, Malinverni, Raffaele, Regenass, Stephan, Dollenmaier, Guenter, Hirsch, Hans, Martinetti, Gladys, Gorgiewski, Meri, Bourlière, Marc, Poynard, Thierry, Theodorou, Ioannis, Abel, Laurent, Pol, Stanislas, Dufour, Jean-François, Negro, Francesco

“…Genetic polymorphisms near IL28B are associated with spontaneous and treatment‐induced clearance of hepatitis C virus (HCV), two processes that require the…”
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Ledipasvir and sofosbuvir plus ribavirin in patients with genotype 1 or 4 hepatitis C virus infection and advanced liver disease: a multicentre, open-label, randomised, phase 2 trial by Manns, Michael, Prof, Samuel, Didier, Prof, Gane, Edward J, Prof, Mutimer, David, Prof, McCaughan, Geoff, Prof, Buti, Maria, Prof, Prieto, MartÍn, MD, Calleja, José Luis, MD, Peck-Radosavljevic, Markus, Prof, Müllhaupt, Beat, Prof, Agarwal, Kosh, MD, Angus, Peter, Prof, Yoshida, Eric M, MD, Colombo, Massimo, Prof, Rizzetto, Mario, Prof, Dvory-Sobol, Hadas, PhD, Denning, Jill, MA, Arterburn, Sarah, MS, Pang, Phillip S, MD, Brainard, Diana, MD, McHutchison, John G, MD, Dufour, Jean-François, MD, Van Vlierberghe, Hans, Prof, van Hoek, Bart, Prof, Forns, Xavier, MD

“…Summary Background Treatment options are limited for patients infected by hepatitis C virus (HCV) with advanced liver disease. We assessed the safety and…”
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Modelling the microelimination of chronic hepatitis C in the canton of Bern, Switzerland: Reaching the Swiss Hepatitis Strategy goals despite the impact of the COVID 19 pandemic by Schorr, Olivier, Blach, Sarah, Thurnheer, Christine, Ruis, Christian, Dufour, Jean-Francois

“…Aims of the study Since 2014, the Swiss Hepatitis Strategy (SHS) has targeted the elimination of Hepatitis C Virus (HCV) in Switzerland. The epidemiology of…”
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HCV disease burden and population segments in Switzerland by Bihl, Florian, Bruggmann, Philip, Castro Batänjer, Erika, Dufour, Jean‐Francois, Lavanchy, Daniel, Müllhaupt, Beat, Negro, Francesco, Razavi, Homie, Scheidegger, Claude, Semela, David, Semmo, Nasser, Blach, Sarah

“…Background Switzerland has made strides towards hepatitis C virus elimination, but as of 2019, elimination was not guaranteed. However, political interest in…”
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The impact of perceived donor liver quality on post‐transplant outcome by Dirchwolf, Melisa, Becchetti, Chiara, Stampf, Susanne, Haldimann, Christa, Immer, Franz, Beyeler, Franziska, Toso, Christian, Dutkowski, Philipp, Candinas, Daniel, Dufour, Jean‐Francois, Banz, Vanessa

“…Background We analysed the impact of perceived liver donor quality on transplant recipient outcomes. Methods this prospective cohort study included all…”
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COVID-19 in Liver Transplant Recipients: A Systematic Review by Becchetti, Chiara, Gschwend, Sarah Gabriela, Dufour, Jean-François, Banz, Vanessa

“…Liver transplant (LT) recipients are considered a vulnerable population amidst the COVID-19 pandemic. To date, available data have been heterogeneous and…”
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Retreatment of patients who failed glecaprevir/pibrentasvir treatment for hepatitis C virus infection by Wyles, David, Weiland, Ola, Yao, Betty, Weilert, Frank, Dufour, Jean-Francois, Gordon, Stuart C., Stoehr, Albrecht, Brown, Ashley, Mauss, Stefan, Zhang, Zhenzhen, Pilot-Matias, Tami, Rodrigues, Lino, Mensa, Federico J, Poordad, Fred

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PTEN Down‐Regulation Promotes β‐Oxidation to Fuel Hypertrophic Liver Growth After Hepatectomy in Mice by Kachaylo, Ekaterina, Tschuor, Christoph, Calo, Nicolas, Borgeaud, Nathalie, Ungethüm, Udo, Limani, Perparim, Piguet, Anne‐Christine, Dufour, Jean‐Francois, Foti, Michelangelo, Graf, Rolf, Clavien, Pierre A., Humar, Bostjan

“…In regenerating liver, hepatocytes accumulate lipids before the major wave of parenchymal growth. This transient, regeneration‐associated steatosis (TRAS) is…”
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Hepatitis C virus infection triggers a tumor‐like glutamine metabolism by Lévy, Pierre L., Duponchel, Sarah, Eischeid, Hannah, Molle, Jennifer, Michelet, Maud, Diserens, Gaëlle, Vermathen, Martina, Vermathen, Peter, Dufour, Jean‐Francois, Dienes, Hans‐Peter, Steffen, Hans‐Michael, Odenthal, Margarete, Zoulim, Fabien, Bartosch, Birke

“…Chronic infection with hepatitis C virus (HCV) is one of the main causes of hepatocellular carcinoma. However, the molecular mechanisms linking the infection…”
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Clinical features and prognostic factors of spinal cord sarcoidosis: a multicenter observational study of 20 BIOPSY-PROVEN patients by Durel, Cécile-Audrey, Marignier, Romain, Maucort-Boulch, Delphine, Iwaz, Jean, Berthoux, Emilie, Ruivard, Marc, André, Marc, Le Guenno, Guillaume, Pérard, Laurent, Dufour, Jean-François, Turcu, Alin, Antoine, Jean-Christophe, Camdessanche, Jean-Philippe, Delboy, Thierry, Sève, Pascal

“…Sarcoidosis of the spinal cord is a rare disease. The aims of this study are to describe the features of spinal cord sarcoidosis (SCS) and identify prognostic…”
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Machine learning approaches to enhance diagnosis and staging of patients with MASLD using routinely available clinical information by McTeer, Matthew, Applegate, Douglas, Mesenbrink, Peter, Ratziu, Vlad, Schattenberg, Jörn M, Bugianesi, Elisabetta, Geier, Andreas, Romero Gomez, Manuel, Dufour, Jean-Francois, Ekstedt, Mattias, Francque, Sven, Yki-Jarvinen, Hannele, Allison, Michael, Valenti, Luca, Miele, Luca, Pavlides, Michael, Cobbold, Jeremy, Papatheodoridis, Georgios, Holleboom, Adriaan G, Tiniakos, Dina, Brass, Clifford, Anstee, Quentin M, Missier, Paolo

“…Metabolic dysfunction Associated Steatotic Liver Disease (MASLD) outcomes such as MASH (metabolic dysfunction associated steatohepatitis), fibrosis and…”
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A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC? by Eldafashi, Nardeen, Darlay, Rebecca, Shukla, Ruchi, McCain, Misti Vanette, Watson, Robyn, Liu, Yang Lin, McStraw, Nikki, Fathy, Moustafa, Fawzy, Michael Atef, Zaki, Marco Y W, Daly, Ann K, Maurício, João P, Burt, Alastair D, Haugk, Beate, Cordell, Heather J, Bianco, Cristiana, Dufour, Jean-François, Valenti, Luca, Anstee, Quentin M, Reeves, Helen L

“…Obesity and non-alcoholic fatty liver disease (NAFLD) are contributing to the global rise in deaths from hepatocellular carcinoma (HCC). The pathogenesis of…”
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