Search Results - "Dufield, Robert L."

The Dual Role of Lipids of the Lipoproteins in Trumenba, a Self-Adjuvanting Vaccine Against Meningococcal Meningitis B Disease by Luo, Yin, Friese, Olga V., Runnels, Herbert A., Khandke, Lakshmi, Zlotnick, Gary, Aulabaugh, Ann, Gore, Thomas, Vidunas, Eugene, Raso, Stephen W., Novikova, Elena, Byrne, Emilia, Schlittler, Michael, Stano, Donald, Dufield, Robert L., Kumar, Sandeep, Anderson, Annaliesa S., Jansen, Kathrin U, Rouse, Jason C.

“…ABSTRACT Trumenba (bivalent rLP2086) is a vaccine licensed for the prevention of meningococcal meningitis disease caused by Neisseria meningitidis serogroup B…”
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Separation by hydrophobic interaction chromatography and structural determination by mass spectrometry of mannosylated glycoforms of a recombinant transferrin-exendin-4 fusion protein from yeast by Zolodz, Melissa D., Herberg, John T., Narepekha, Halyna E., Raleigh, Emily, Farber, Matthew R., Dufield, Robert L., Boyle, Denis M.

“…Obtaining sufficient amounts of pure glycoprotein variants to characterize their structures is an important goal in both functional biology and the…”
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Evolution of a comprehensive, orthogonal approach to sequence variant analysis for biotherapeutics by Lin, T. Jennifer, Beal, Kathryn M., Brown, Paul W., DeGruttola, Heather S., Ly, Mellisa, Wang, Wenge, Chu, Chia H., Dufield, Robert L., Casperson, Gerald F., Carroll, James A., Friese, Olga V., Figueroa, Bruno, Marzilli, Lisa A., Anderson, Karin, Rouse, Jason C.

“…Amino acid sequence variation in protein therapeutics requires close monitoring during cell line and cell culture process development. A cross-functional team…”
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Integrated solution to purification challenges in the manufacture of a soluble recombinant protein in E. coli by Caparon, Maire H, Rust, Kevin J, Hunter, Alan K, McLaughlin, Joseph K, Thomas, Kristen E, Herberg, John T, Shell, Robert E, Lanter, Paul B, Bishop, Bruce F, Dufield, Robert L, Wang, Xing, Ho, Sa V

“…Apolipoprotein A 1 Milano (ApoA-1M), the protein component of a high-density lipoprotein (HDL) mimic with promising potential for reduction of atherosclerotic…”
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Reaction kinetics and optimization of the copper-catalyzed oxidation of ApoA-1M by Ho, Sa V., McLaughlin, Joseph K., Thomas, Kristen E., Suda, Eric, Herberg, John T., Dufield, Robert L., Hunter, Alan K.

“…This paper summarizes the development of an optimized Cu(II)-catalyzed oxidation process for the dimer formation of ApoA-1M, the protein component of an HDL…”
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Separation of product associating E. coli host cell proteins OppA and DppA from recombinant apolipoprotein A-IMilano in an industrial HIC unit operation by Hunter, Alan K., Wang, Xing, Suda, Eric J., Herberg, John T., Shell, Robert E., Thomas, Kristin E., Dufield, Robert L., Gustafson, Mark E., Mozier, Ned M., Ho, Sa. V.

“…We have shown how product associating E. coli host cell proteins (HCPs) OppA and DppA can be substantially separated from apolipoprotein A‐IMilano (apo A‐IM)…”
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Separation of product associating E. coli host cell proteins OppA and DppA from recombinant apolipoprotein A‐I Milano in an industrial HIC unit operation by Hunter, Alan K., Wang, Xing, Suda, Eric J., Herberg, John T., Shell, Robert E., Thomas, Kristin E., Dufield, Robert L., Gustafson, Mark E., Mozier, Ned M., Ho, Sa. V.

“…Abstract We have shown how product associating E. coli host cell proteins (HCPs) OppA and DppA can be substantially separated from apolipoprotein A‐I Milano…”
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Separation of Product Associating E. coli Host Cell Proteins OppA and DppA from Recombinant Apolipoprotein A-Imilano in an Industrial HIC Unit Operation: Biomass Refining Consortium for Applied Fundamentals and Innovation (CAFI) by HUNTER, Alan K, XING WANG, SUDA, Eric J, HERBERG, John T, SHELL, Robert E, THOMAS, Kristin E, DUFIELD, Robert L, GUSTAFSON, Mark E, MOZIER, Ned M, HO, Sa. V

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Separation of product associating E. coli host cell proteins OppA and DppA from recombinant apolipoprotein A-I(Milano) in an industrial HIC unit operation by Hunter, Alan K, Wang, Xing, Suda, Eric J, Herberg, John T, Shell, Robert E, Thomas, Kristin E, Dufield, Robert L, Gustafson, Mark E, Mozier, Ned M, Ho, Sa V

“…We have shown how product associating E. coli host cell proteins (HCPs) OppA and DppA can be substantially separated from apolipoprotein A-I(Milano) (apo…”
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