Search Results - "Duffy, Nicola A."

Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1 by Green, Brian D., Irwin, Nigel, Duffy, Nicola A., Gault, Victor A., O'Harte, Finbarr P.M., Flatt, Peter R.

“…GLP-1 and GIP are insulin-releasing ‘incretin’ hormones inactivated following degradation by dipeptidyl peptidase IV. Incretin hormone analogues resistant to…”
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Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects by McKillop, Aine M, Duffy, Nicola A, Lindsay, John R, O’Harte, Finbarr P.M, Bell, Patrick M, Flatt, Peter R

“…Abstract Dipeptidyl peptidase (DPP-IV) rapidly metabolises hormones such as glucagon-like peptide-1(7-36)amide. This study evaluated circulating DPP-IV…”
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Effects of antidiabetic drugs on dipeptidyl peptidase IV activity: Nateglinide is an inhibitor of DPP IV and augments the antidiabetic activity of glucagon-like peptide-1 by Duffy, Nicola A., Green, Brian D., Irwin, Nigel, Gault, Victor A., McKillop, Aine M., O'Harte, Finbarr P.M., Flatt, Peter R.

“…Dipeptidyl peptidase IV (DPP IV) is the primary inactivator of glucoregulatory incretin hormones. This has lead to development of DPP IV inhibitors as a new…”
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Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation by McKillop, Aine M, Duffy, Nicola A, Lindsay, John R, Green, Brian D, Patterson, S, O'Harte, Finbarr P M, Bell, Patrick M, Flatt, Peter R

“…BackgroundNateglinide restores early-phase insulin secretion to feeding and reduces postprandial hyperglycaemia in type 2 diabetes. This study evaluated the…”
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