Search Results - "Duffy, Colm D"
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Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism
Published in Nature chemistry (01-04-2015)“…A minimal cell can be thought of as comprising informational, compartment-forming and metabolic subsystems. To imagine the abiotic assembly of such an overall…”
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Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation
Published in Nature chemistry (01-05-2013)“…The recent synthesis of pyrimidine ribonucleoside-2′,3′-cyclic phosphates under prebiotically plausible conditions has strengthened the case for the…”
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Synthesis and Biological Evaluation of Pyridine-Containing Lipoxin A4 Analogues
Published in ChemMedChem (06-04-2010)“…A short and efficient synthesis of new pyridine‐containing lipoxin A4 analogues was developed. These analogues induce phagocytosis of apoptotic…”
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ZrCl4 as an Efficient Catalyst for a Novel One-Pot Protection/Deprotection Synthetic Methodology
Published in Journal of organic chemistry (15-08-2008)“…A catalytic quantity of ZrCl4 (20 mol %) was found to be an efficient catalyst for the one-pot esterification and deprotection of…”
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Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling
Published in Journal of the American Chemical Society (06-03-2019)“…The main aim of origins of life research is to find a plausible sequence of transitions from prebiotic chemistry to nascent biology. In this context,…”
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Solid-Phase Synthesis and Hybrization Behavior of Partially 2′/3′‑O‑Acetylated RNA Oligonucleotides
Published in Journal of organic chemistry (18-04-2014)“…Synthesis of partially 2′/3′-O-acetylated oligoribonucleotides has been accomplished by using a 2′/3′-O-acetyl orthogonal protecting group strategy in which…”
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ZrCl 4 as an Efficient Catalyst for a Novel One-Pot Protection/Deprotection Synthetic Methodology
Published in Journal of organic chemistry (01-08-2008)Get full text
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Synthesis and Biological Evaluation of Pyridine‐Containing Lipoxin A 4 Analogues
Published in ChemMedChem (06-04-2010)Get full text
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Asymmetric Synthesis of (+)-Tanikolide and the β-Methyl-Substituted Analogues of (+)-Tanikolide and (-)-Malyngolide
Published in European Journal of Organic Chemistry (01-12-2011)“…The δ‐lactone‐containing natural product (+)‐tanikolide, a brine shrimp toxin and antifungal compound, was synthesized in nine steps with an overall yield of…”
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