Search Results - "Duffy, A G"

Immunological off-target effects of standard treatments in gastrointestinal cancers by Duffy, A.G., Greten, T.F.

“…The effects on immune cells and the inflammatory microenvironment of commonly applied cancer treatments (chemotherapeutic or biologic agents, interventional…”
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Deep-sea scavenging amphipod assemblages from the submarine canyons of the Western Iberian Peninsula by Duffy, G. A, Horton, T, Billett, D. S. M

“…Submarine canyons have often been identified as hotspots of secondary production with the potential to house distinct faunal assemblages and idiosyncratic…”
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Modulation of tumor eIF4E by antisense inhibition: A phase I/II translational clinical trial of ISIS 183750—an antisense oligonucleotide against eIF4E—in combination with irinotecan in solid tumors and irinotecan‐refractory colorectal cancer by Duffy, A.G., Makarova‐Rusher, O.V., Ulahannan, S.V., Rahma, O.E., Fioravanti, S., Walker, M., Abdullah, S., Raffeld, M., Anderson, V., Abi‐Jaoudeh, N., Levy, E., Wood, B.J., Lee, S., Tomita, Y., Trepel, J.B., Steinberg, S.M., Revenko, A.S., MacLeod, A.R., Peer, C.J., Figg, W.D., Greten, T.F.

“…The eukaryotic translation initiation factor 4E (eIF4E) is a potent oncogene that is found to be dysregulated in 30% of human cancer, including colorectal…”
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A phase II study of TRC105 in patients with hepatocellular carcinoma who have progressed on sorafenib by Duffy, AG, Ulahannan, SV, Cao, L, Rahma, OE, Makarova-Rusher, OV, Kleiner, DE, Fioravanti, S, Walker, M, Carey, S, Yu, Y, Venkatesan, AM, Turkbey, B, Choyke, P, Trepel, J, Bollen, KC, Steinberg, SM, Figg, WD, Greten, TF

“…Background Endoglin is an endothelial cell membrane receptor essential for angiogenesis and highly expressed on the vasculature of many tumor types, including…”
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Recent advances in immune-based approaches for the treatment of esophagogastric cancer by Weadick, C S, Duffy, A G, Kelly, R J

“…The year 2021 will be remembered as a transformational year in the management of both esophageal and gastric cancers. Decades of failed clinical trials had…”
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Explicitly integrating a third dimension in marine species distribution modelling by Duffy, G. A., Chown, S. L.

“…Marine species distribution modelling (SDM) studies frequently pair surface environmental variables with deep-water occurrence records despite the disparity of…”
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Treating Hepatobiliary Cancer: The Immunologic Approach by Duffy, A G, Greten, T F

“…Hepatobiliary cancer comprises a heterogeneous group of malignancies in which the standard treatments for advanced disease are minimally effective and evolve…”
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Investigating a clinically actionable BRAF mutation for monitoring low-grade serous ovarian cancer: A case report by Silva, R., Moran, B., Das, S., Mulligan, N., Doughty, M., Treacy, A., Sheahan, K., Kelly, C.M., Duffy, A.G., Perry, A.S., Brennan, D.J.

“…Low-grade serous ovarian cancer (LGSOC) poses a specific clinical challenge due to advanced presentation at diagnosis and the lack of effective systemic…”
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Mixing and corrosion in Ni implanted with Pt through a sacrificial layer of alumina by Duffy, A.G., Clapham, L., Ridgway, M.C., Whitton, J.L.

“…Sputtering is a significant problem in the high-dose implantation of heavy ions, limiting the achievable peak concentration. To increase the retained dose, a…”
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Taxane-resistant lymphoepithelial-like carcinoma: excellent response to VIP chemotherapy by Duffy, A G, Wyse, G, Horgan, A M, O'Keefe, M, O'Reilly, S, Breathnach, O S

“…Lymphoepithelial-like carcinoma is a rare tumour type. The optimal treatment for this disease is not known. No effective therapies are described in the…”
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Bleeding events and eligibility requirements in studies evaluating an antiangiogenic agent in hepatocellular carcinoma (HCC) by Duffy, A. G., Greten, T.

“…Abstract only 310 Background: The presence of cirrhosis means an increased baseline potential risk of bleeding in patients with HCC. With the establishment of…”
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Television observations of the 1984 Orionid shower by Duffy, A. G., Hawkes, R. L., Jones, J.

“…Absolute magnitudes, photometric masses, trajectory information and light curves are presented for a sample of 17 meteors from the 1984 Orionid shower. These…”
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The determination of shower meteor parameters from single station observations by Duffy, A. G., Hawkes, R. L., Jones, J.

“…An effective method for identifying shower meteors and determining atmospheric trajectories from single station observations has been developed and tested with…”
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Size-dependent directed social learning in nine-spined sticklebacks by Duffy, Grant A., Pike, Thomas W., Laland, Kevin N.

“…To forage efficiently in a patchy environment animals must make informed decisions concerning in which patches to forage, for which the behaviour of other…”
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Early disease progression in a phase I study of bortezomib (B), cetuximab (C), and intensity-modulated radiation therapy (IMRT) for squamous cell carcinoma of the head and neck (SCCHN) by Van Waes, C., Duffy, A. G., Simone, N. L., Gibson, M. K., Arai, Y., Rudy, S. F., Cooley-Zgela, T., Nyati, M., Wright, J. J., Argiris, A.

“…Abstract only…”
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A pilot trial of oral topotecan (TPT) in patients with refractory advanced solid neoplasms expressing HIF-1α by Duffy, A. G., Melillo, G., Turkbey, B., Allen, D., Choyke, P. L., Chen, C., Raffeld, M., Doroshow, J. H., Murgo, A., Kummar, S.

“…Abstract only…”
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High-dose implantation of Pt ions into Ni using the sacrificial layer technique: A comparison of Al and Al2O3 sacrificial layers by Duffy, A.G., Clapham, L., Whitton, J.L., Ridgway, M.C.

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Investigating a clinically actionable BRAF mutation for monitoring low-grade serous ovarian cancer: A case report by Silva, R, Moran, B, Das, S, Mulligan, N, Doughty, M, Treacy, A, Sheahan, K, Kelly, C M, Duffy, A G, Perry, A S, Brennan, D J

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The Gradual Release of Responsibility in Literacy Research and Practice by McVee, Mary, Ortlieb, Evan, Reichenberg, Jennifer, Pearson, P. David

“…This edited volume discusses how the Gradual Release of Responsibility model evolved and has been applied, how it benefits learners and teachers, and how it…”
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An innovative special study module utilizing computer-based learning in obstetrics and gynaecology by Kevelighan, E H, Duffy, S R G, Harris, R M, Cole, A J

“…The General Medical Council has acknowledged the need for training in information technology to assist in continued education and learning. As part of our…”
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