Search Results - "Duell, Anna K"

Benzene formation in electronic cigarettes by Pankow, James F, Kim, Kilsun, McWhirter, Kevin J, Luo, Wentai, Escobedo, Jorge O, Strongin, Robert M, Duell, Anna K, Peyton, David H

“…The heating of the fluids used in electronic cigarettes ("e-cigarettes") used to create "vaping" aerosols is capable of causing a wide range of degradation…”
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Nicotine in tobacco product aerosols: 'It's déjà vu all over again' by Duell, Anna K, Pankow, James F, Peyton, David H

“…The distribution of nicotine among its free-base (fb) and protonated forms in aerosolised nicotine affects inhalability. It has been manipulated in tobacco…”
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Quantification of PARP7 Protein Levels and PARP7 Inhibitor Target Engagement in Cells Using a Split Nanoluciferase System by Duell, Anna K, Sanderson, Daniel J, Cohen, Michael S

“…PARP7 is an enzyme that catalyzes mono-ADP-ribosylation (MARylation), is a critical regulator of type I interferon signaling, and has emerged as an…”
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Effects of Common e‑Liquid Flavorants and Added Nicotine on Toxicant Formation during Vaping Analyzed by 1H NMR Spectroscopy by Kerber, Paul J., Duell, Anna K., Powers, Marley, Strongin, Robert M., Peyton, David H.

“…A broad variety of e-liquids are used by e-cigarette consumers. Additives to the e-liquid carrier solvents, propylene glycol and glycerol, often include…”
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Sucralose-Enhanced Degradation of Electronic Cigarette Liquids during Vaping by Duell, Anna K, McWhirter, Kevin J, Korzun, Tetiana, Strongin, Robert M, Peyton, David H

“…Electronic cigarette liquids (e-liquids) with sweetener additives such as sucralose, a synthetic chlorinated disaccharide, are popular among some e-cigarette…”
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Ratio of Propylene Glycol to Glycerol in E-Cigarette Reservoirs Is Unchanged by Vaping As Determined by 1 H NMR Spectroscopy by Kerber, Paul J, Duell, Anna K, Peyton, David H

“…E-cigarette liquids (e-liquids) contain propylene glycol (PG) and/or glycerol (GL) to deliver flavorants/nicotine. It has recently been suggested that the…”
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Determination of ( R )-(+)- and ( S )-(-)-Nicotine Chirality in Puff Bar E-Liquids by 1 H NMR Spectroscopy, Polarimetry, and Gas Chromatography-Mass Spectrometry by Duell, Anna K, Kerber, Paul J, Luo, Wentai, Peyton, David H

“…Tobacco products generally contain tobacco-derived nicotine (TDN; having ∼99+% ( )-(-)-nicotine). Recent United States regulation has led some producers to…”
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Determination of (R)‑(+)- and (S)‑(−)-Nicotine Chirality in Puff Bar E‑Liquids by 1H NMR Spectroscopy, Polarimetry, and Gas Chromatography–Mass Spectrometry by Duell, Anna K, Kerber, Paul J, Luo, Wentai, Peyton, David H

“…Tobacco products generally contain tobacco-derived nicotine (TDN; having ∼99+% (S)-(−)-nicotine). Recent United States regulation has led some producers to…”
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Effects of Common e-Liquid Flavorants and Added Nicotine on Toxicant Formation during Vaping Analyzed by 1 H NMR Spectroscopy by Kerber, Paul J, Duell, Anna K, Powers, Marley, Strongin, Robert M, Peyton, David H

“…A broad variety of e-liquids are used by e-cigarette consumers. Additives to the e-liquid carrier solvents, propylene glycol and glycerol, often include…”
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Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling by Sanderson, Daniel J, Rodriguez, Kelsie M, Bejan, Daniel S, Olafsen, Ninni E, Bohn, Inga D, Kojic, Ana, Sundalam, Sunil, Siordia, Ivan R, Duell, Anna K, Deng, Nancy, Schultz, Carsten, Grant, Denis M, Matthews, Jason, Cohen, Michael S

“…The mono-ADP-ribosyltransferase PARP7 has emerged as a key negative regulator of cytosolic NA-sensors of the innate immune system. We apply a rational design…”
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Free-Base Nicotine Fraction αfb in Non-Aqueous versus Aqueous Solutions: Electronic Cigarette Fluids Without versus With Dilution with Water by Pankow, James F, Duell, Anna K, Peyton, David H

“…An important design aspect of electronic cigarettes (“e-cigarettes”) is the nature of the acid/base chemistry in the e-liquid phase. E-liquids having…”
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Correction to Free-Base Nicotine Determination in Electronic Cigarette Liquids by 1H NMR Spectroscopy by Duell, Anna K, Pankow, James F, Peyton, David H

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Correction to Free-Base Nicotine Determination in Electronic Cigarette Liquids by 1 H NMR Spectroscopy by Duell, Anna K, Pankow, James F, Peyton, David H

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Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors by Arnold, Moriah R, Langelier, Marie-France, Gartrell, Jessica, Kirby, Ilsa T, Sanderson, Daniel J, Bejan, Daniel S, Šileikytė, Justina, Sundalam, Sunil K, Nagarajan, Shanthi, Marimuthu, Parthiban, Duell, Anna K, Shelat, Anang A, Pascal, John M, Cohen, Michael S

“…Allosteric coupling between the DNA binding site to the NAD -binding pocket drives PARP-1 activation. This allosteric communication occurs in the reverse…”
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Free-Base Nicotine Determination in Electronic Cigarette Liquids by 1 H NMR Spectroscopy by Duell, Anna K, Pankow, James F, Peyton, David H

“…E-liquids usually contain significant nicotine, which will exist primarily in two forms, monoprotonated and free-base, the proportions of which are alterable…”
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Free-Base Nicotine Determination in Electronic Cigarette Liquids by 1H NMR Spectroscopy by Duell, Anna K, Pankow, James F, Peyton, David H

“…E-liquids usually contain significant nicotine, which will exist primarily in two forms, monoprotonated and free-base, the proportions of which are alterable…”
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Boiling points of the propylene glycol + glycerol system at 1 atmosphere pressure: 188.6-292 °C without and with added water or nicotine by Duell, Anna K., Pankow, James F., Gillette, Samantha M., Peyton, David H.

“…In electronic cigarettes ("electronic nicotine delivery systems", ENDS), mixtures of propylene glycol (PG) and/or glycerol (GL; aka "vegetable glycerin", VG)…”
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Free-Base Nicotine Is Nearly Absent in Aerosol from IQOS Heat-Not-Burn Devices, As Determined by 1 H NMR Spectroscopy by Meehan-Atrash, Jiries, Duell, Anna K, McWhirter, Kevin J, Luo, Wentai, Peyton, David H, Strongin, Robert M

“…Heat-not-burn products, eg, I quit ordinary smoking (IQOS), are becoming popular alternative tobacco products. The nicotine aerosol protonation state has…”
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Ratio of Propylene Glycol to Glycerol in E‑Cigarette Reservoirs Is Unchanged by Vaping As Determined by 1H NMR Spectroscopy by Kerber, Paul J, Duell, Anna K, Peyton, David H

“…E-cigarette liquids (e-liquids) contain propylene glycol (PG) and/or glycerol (GL) to deliver flavorants/nicotine. It has recently been suggested that the…”
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Free-Base Nicotine Is Nearly Absent in Aerosol from IQOS Heat-Not-Burn Devices, As Determined by 1H NMR Spectroscopy by Meehan-Atrash, Jiries, Duell, Anna K, McWhirter, Kevin J, Luo, Wentai, Peyton, David H, Strongin, Robert M

“…Heat-not-burn products, eg, I quit ordinary smoking (IQOS), are becoming popular alternative tobacco products. The nicotine aerosol protonation state has…”
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