Search Results - "Due, Hanne"
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Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review
Published in Cancer chemotherapy and pharmacology (01-09-2019)“…Purpose Vincristine is widely used as anticancer therapy for a variety of hematological malignancies. The treatment is limited by progressive…”
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2
Hsp90 inhibition sensitizes DLBCL cells to cisplatin
Published in Cancer chemotherapy and pharmacology (01-04-2022)“…Purpose Platinum-containing therapy is standard treatment for relapsed Diffuse Large B-Cell Lymphoma (DLBCL). However, the efficacy of treatment is limited by…”
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MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index
Published in BMC cancer (20-03-2020)“…Treatment resistance is a major clinical challenge of diffuse large B-cell lymphoma (DLBCL) where approximately 40% of the patients have refractory disease or…”
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4
miR-155 as a Biomarker in B-Cell Malignancies
Published in BioMed research international (01-01-2016)“…MicroRNAs have the potential to be useful biomarkers in the development of individualized treatment since they are easy to detect, are relatively stable during…”
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Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
Published in Molecular oncology (01-09-2020)“…Diffuse large B‐cell lymphoma (DLBCL) is characterized by extensive genetic heterogeneity, and this results in unpredictable responses to the current…”
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Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis
Published in Scientific reports (23-01-2019)“…Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with diverse clinical presentation and outcome. Bio-clinical prognostic models including…”
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CDCA2 Is a Predictive Marker and Mediator of Bortezomib Response in Diffuse Large B-Cell Lymphoma
Published in Blood (02-11-2023)“…Objective: In recent years randomized phase III clinical trials have attempted to improve first-line R-CHOP treatment of diffuse large B-cell lymphoma (DLBCL)…”
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Addition of Drug-Response Specific Micro-RNAs to the International Prognostic Index Improves Prognostic Stratification of GCB-DLBCL Patients Treated with R-CHOP
Published in Blood (13-11-2019)“…Background: Patients with Diffuse large B-cell lymphoma (DLBCL) in approximately 40% of cases suffer from primary refractory disease and treatment induced…”
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CRISPR-Cas9 Knockout Screens Identify DNA Damage Response Pathways and BTK as Essential for Cisplatin Response in Diffuse Large B-Cell Lymphoma
Published in Cancers (02-07-2024)“…The recurrence of diffuse large B-cell lymphoma (DLBCL) has been observed in 40% of cases. The standard of care for refractory/relapsed DLBCL (RR-DLBCL) is…”
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Beneficial Effect of Microrna-155 in Vincristine Response and Clinical Outcome in Especially GCB Diffuse Large B-Cell Lymphoma
Published in Blood (08-12-2017)“…▪ R-CHOP is standard treatment for previously untreated diffuse large B-cell lymphoma (DLBCL). Approximately 35-40% of patients relapse following R-CHOP due to…”
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High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients
Published in Oncotarget (22-01-2019)“…Survival of diffuse large B-cell lymphoma (DLBCL) patients has improved by inclusion of rituximab. Refractory/recurrent disease caused by treatment resistance…”
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A bendamustine resistance gene signature in diffuse large B-cell lymphoma and multiple myeloma
Published in Cancer drug resistance (01-01-2021)“…: Bendamustine is primarily used for treatment of indolent lymphomas but has shown efficacy in some patients with diffuse large B-cell lymphoma (DLBCL) and…”
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MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma
Published in Blood advances (09-04-2019)“…A major clinical challenge of diffuse large B-cell lymphoma (DLBCL) is that up to 40% of patients have refractory disease or relapse after initial response to…”
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A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis
Published in Blood advances (25-09-2018)“…Despite the recent progress in treatment of multiple myeloma (MM), it is still an incurable malignant disease, and we are therefore in need of new risk…”
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Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission
Published in Experimental hematology & oncology (11-01-2017)“…The concept of precision medicine in cancer includes individual molecular studies to predict clinical outcomes. In the present N = 1 case we retrospectively…”
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Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission
Published in Experimental hematology & oncology (01-01-2017)“…BACKGROUNDThe concept of precision medicine in cancer includes individual molecular studies to predict clinical outcomes. In the present N = 1 case we…”
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