Search Results - "Dudnakova, Tatiana"
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Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
Published in Cell (25-04-2013)“…MicroRNAs (miRNAs) play key roles in gene regulation, but reliable bioinformatic or experimental identification of their targets remains difficult. To provide…”
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Transcription factor Wilms' tumor 1 regulates developmental RNAs through 3' UTR interaction
Published in Genes & development (15-02-2017)“…Wilms' tumor 1 (WT1) is essential for the development and homeostasis of multiple mesodermal tissues. Despite evidence for post-transcriptional roles, no…”
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Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development
Published in Cell research (01-09-2011)“…Methylation of cytosine is a DNA modification associated with gene repression. Recently, a novel cytosine modification, 5-hydroxymethylcytosine (5-hmC) has…”
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Importance of Long Non-coding RNAs in the Development and Disease of Skeletal Muscle and Cardiovascular Lineages
Published in Frontiers in cell and developmental biology (18-10-2019)“…The early mammalian embryo is characterized by the presence of three germ layers-the outer ectoderm, middle mesoderm and inner endoderm. The mesoderm is…”
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Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression
Published in Molecular therapy. Nucleic acids (11-06-2024)“…Epigenetic processes involving long non-coding RNAs regulate endothelial gene expression. However, the underlying regulatory mechanisms causing endothelial…”
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Transient Accumulation of 5-Carboxylcytosine Indicates Involvement of Active Demethylation in Lineage Specification of Neural Stem Cells
Published in Cell reports (Cambridge) (12-06-2014)“…5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to…”
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Mapping targets for small nucleolar RNAs in yeast
Published in Wellcome open research (2018)“…Recent analyses implicate changes in the expression of the box C/D class of small nucleolar RNAs (snoRNAs) in several human diseases. Here we report the…”
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Mapping targets for small nucleolar RNAs in yeast
Published in Wellcome open research (01-09-2018)“…Background: Recent analyses implicate changes in the expression of the box C/D class of small nucleolar RNAs (snoRNAs) in several human diseases. Methods: Here…”
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Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
Published in Disease models & mechanisms (01-08-2015)“…Wilms' tumours, paediatric kidney cancers, are the archetypal example of tumours caused through the disruption of normal development. The genetically…”
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Methods to Identify and Validate WT1-RNA Interaction
Published in Methods in molecular biology (Clifton, N.J.) (2016)“…Tumor suppressor protein, Wt1 is a transcription factor that binds to DNA sequence similar to the Early Growth Response gene, EGR1 consensus binding sequence…”
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Epigenetic control of vascular endothelial function revealed by multi-omics
Published in European heart journal (01-03-2024)Get full text
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Rio1 mediates ATP-dependent final maturation of 40S ribosomal subunits
Published in Nucleic acids research (29-10-2014)“…During the last step in 40S ribosome subunit biogenesis, the PIN-domain endonuclease Nob1 cleaves the 20S pre-rRNA at site D, to form the mature 18S rRNAs…”
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HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA
Published in Molecular cell (19-07-2018)“…The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral axon injury. HuD interacts with many mRNAs, altering both stability and…”
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MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease
Published in Circulation research (16-04-2021)“…[Figure: see text]…”
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Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
Published in Development (Cambridge) (15-08-2015)Get full text
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Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly
Published in Molecular cell (12-12-2013)“…In vivo UV crosslinking identified numerous preribosomal RNA (pre-rRNA) binding sites for the large, highly conserved ribosome synthesis factor Rrp5…”
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Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1 mutants
Published in Disease models & mechanisms (01-01-2015)“…Wilms' tumours, paediatric kidney cancers, are the archetypal example of tumours caused through the disruption of normal development. The genetically best…”
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