Search Results - "Dudley, Kevin J"
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Offspring of mothers fed a high fat diet display hepatic cell cycle inhibition and associated changes in gene expression and DNA methylation
Published in PloS one (11-07-2011)“…The association between an adverse early life environment and increased susceptibility to later-life metabolic disorders such as obesity, type 2 diabetes and…”
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Sex and tissue specific gene expression patterns identified following de novo transcriptomic analysis of the Norway lobster, Nephrops norvegicus
Published in BMC genomics (16-08-2017)“…The Norway lobster, Nephrops norvegicus, is economically important in European fisheries and is a key organism in local marine ecosystems. Despite…”
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Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family
Published in BMC biology (24-05-2023)“…The ShK toxin from Stichodactyla helianthus has established the therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin families…”
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The Rapid Methylation of T-DNAs Upon Agrobacterium Inoculation in Plant Leaves
Published in Frontiers in plant science (15-03-2019)“…has been foundational in the development of transgenic plants for both agricultural biotechnology and plant molecular research. However, the transformation…”
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The widely used Nicotiana benthamiana 16c line has an unusual T-DNA integration pattern including a transposon sequence
Published in PloS one (23-02-2017)“…Nicotiana benthamiana is employed around the world for many types of research and one transgenic line has been used more extensively than any other. This line,…”
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Chromatin immunoprecipitation (ChIP) method for non-model fruit flies (Diptera: Tephritidae) and evidence of histone modifications
Published in PloS one (15-03-2018)“…Interactions between DNA and proteins located in the cell nucleus play an important role in controlling physiological processes by specifying, augmenting and…”
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7
Equine glucagon-like peptide-1 receptor physiology
Published in PeerJ (San Francisco, CA) (29-01-2018)“…Equine metabolic syndrome (EMS) is associated with insulin dysregulation, which often manifests as post-prandial hyperinsulinemia. Circulating concentrations…”
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Specific rolling circle amplification of low-copy human polyomaviruses BKV, HPyV6, HPyV7, TSPyV, and STLPyV
Published in Journal of virological methods (01-04-2015)“…•Development of a RCA method to specifically amplify low-copy polyomavirus genomes.•BKV genome could be amplified 1×108-fold from as little as 10 copies in…”
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Genome-Wide Analysis in a Murine Dnmt1 Knockdown Model Identifies Epigenetically Silenced Genes in Primary Human Pituitary Tumors
Published in Molecular cancer research (01-10-2008)“…DNA methylation at promoter CpG islands (CGI) is an epigenetic modification associated with inappropriate gene silencing in multiple tumor types. In the…”
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Non-CG DNA methylation marks the transition from pupa to adult in Helicoverpa armigera
Published in Insect molecular biology (01-10-2024)“…DNA methylation in insects is generally low in abundance, and its role is not well understood. It is often localised in protein coding regions and associated…”
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VPBrowse: Genome‐based representation of MS/MS spectra to quantify 10,000 bovine proteins
Published in Proteomics (Weinheim) (01-07-2024)“…SWATH is a data acquisition strategy acclaimed for generating quantitatively accurate and consistent measurements of proteins across multiple samples. Its…”
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A hot topic: thermophilic plastic biodegradation
Published in Trends in biotechnology (Regular ed.) (01-09-2023)“…Biological degradation of plastic waste is an environmentally and economically friendlier alternative to current recycling practices and enables the cycling of…”
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Epigenetic mechanisms mediating vulnerability and resilience to psychiatric disorders
Published in Neuroscience and biobehavioral reviews (01-06-2011)“…The impact that stressful encounters have upon long-lasting behavioural phenotypes is varied. Whereas a significant proportion of the population will develop…”
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Expression of the GCG gene and secretion of active glucagon‐like peptide‐1 varies along the length of intestinal tract in horses
Published in Equine veterinary journal (01-03-2024)“…Background Active glucagon‐like peptide‐1 (aGLP‐1) has been implicated in the pathogenesis of equine insulin dysregulation (ID), but its role is unclear…”
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A multi-omic Nicotiana benthamiana resource for fundamental research and biotechnology
Published in Nature plants (01-09-2023)“…Nicotiana benthamiana is an invaluable model plant and biotechnology platform with a ~3 Gb allotetraploid genome. To further improve its usefulness and…”
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Paradoxical enhancement of fear extinction memory and synaptic plasticity by inhibition of the histone acetyltransferase p300
Published in The Journal of neuroscience (18-05-2011)“…It is well established that the coordinated regulation of activity-dependent gene expression by the histone acetyltransferase (HAT) family of transcriptional…”
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Author Correction: A multi-omic Nicotiana benthamiana resource for fundamental research and biotechnology
Published in Nature plants (2024)Get full text
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18
Chromatin immunoprecipitation
Published in PloS one (15-03-2018)“…Interactions between DNA and proteins located in the cell nucleus play an important role in controlling physiological processes by specifying, augmenting and…”
Get full text
Journal Article -
19
Chromatin immunoprecipitation and evidence of histone modifications
Published in PloS one (15-03-2018)“…Interactions between DNA and proteins located in the cell nucleus play an important role in controlling physiological processes by specifying, augmenting and…”
Get full text
Journal Article