Search Results - "Dudley, Julia"
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Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day
Published in PloS one (07-03-2011)“…The neurochemical status and hyperactivity of mice lacking functional substance P-preferring NK1 receptors (NK1R-/-) resemble abnormalities in Attention…”
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The behavioural response of mice lacking NK1 receptors to guanfacine resembles its clinical profile in treatment of ADHD
Published in British journal of pharmacology (01-10-2014)“…Background and Purpose Mice with functional ablation of substance P‐preferring neurokinin‐1 receptors (NK1R−/− mice) display behavioural abnormalities…”
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912 Herpes simplex virus in infants under 90 days of age in UK and Ireland: results of the 2019–2022 BPSU study
Published in Archives of disease in childhood (01-07-2023)“…ObjectivesNeonatal herpes simplex virus (HSV) infection is a rare but dangerous condition. Previous national British Paediatric Surveillance Unit (BPSU)…”
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1487 Neonatal HSV disease in infants under 90 days of age in UK and Ireland: BPSU study interim analysis
Published in Archives of disease in childhood (01-10-2021)“…BackgroundNeonatal herpes simplex virus infection is a rare but dangerous condition with a high mortality and morbidity unless recognised and treated early. A…”
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Salmonella Paratyphi B; Public Health and Parental Choice: When to Treat Asymptomatic Carriers of Infection?
Published in The Pediatric infectious disease journal (27-07-2021)Get full text
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Salmonella Paratyphi B; Public Health and Parental Choice: When to Treat Asymptomatic Carriers of Infection?
Published in The Pediatric infectious disease journal (01-10-2021)“…Salmonella Paratyphi B (Paratyphoid B) is a rare infection and a notifiable disease in England. Disease is typically mild, and chronic carriage in children has…”
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Trends in maternal opioid use disorder and neonatal abstinence syndrome in Maine, 2016–2022
Published in Journal of perinatology (01-08-2024)“…Objective To estimate trends in maternal opioid use disorder (OUD) and neonatal abstinence syndrome (NAS) in Maine using the most recent data available. Study…”
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Neonatal Herpes Simplex Virus: Cutaneous Recurrence Is Common on Stopping Prophylactic Suppression Therapy
Published in Journal of the Pediatric Infectious Diseases Society (05-12-2022)“…Abstract Neonatal herpes simplex virus (HSV) infection is a potentially devastating disease. Data on the recurrence of disease while on suppressive therapy are…”
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Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Prescribing Across Europe
Published in Clinical infectious diseases (20-03-2024)“…Abstract Background Optimization of antimicrobial stewardship is key to tackling antimicrobial resistance, which is exacerbated by overprescription of…”
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External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children
Published in Archives of disease in childhood (01-01-2024)“…ObjectiveTo externally validate and update the Feverkids tool clinical prediction model for differentiating bacterial pneumonia and other serious bacterial…”
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Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study
Published in European journal of pediatrics (01-09-2023)“…Children constitute 6–10% of all patients attending the emergency department (ED) by emergency medical services (EMS). However, discordant EMS use in children…”
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Guideline adherence in febrile children below 3 months visiting European Emergency Departments: an observational multicenter study
Published in European journal of pediatrics (01-12-2022)“…Febrile children below 3 months have a higher risk of serious bacterial infections, which often leads to extensive diagnostics and treatment. There is practice…”
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Febrile illness in high-risk children: a prospective, international observational study
Published in European journal of pediatrics (01-02-2023)“…To assess and describe the aetiology and management of febrile illness in children with primary or acquired immunodeficiency at high risk of serious bacterial…”
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Correction to: Febrile illness in high-risk children: a prospective, international observational study
Published in European journal of pediatrics (01-02-2023)Get full text
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Treatment of severe tracheobronchomalacia: Ten-year experience
Published in International journal of pediatric otorhinolaryngology (01-04-2016)“…Abstract Introduction Paediatric tracheobronchomalacia is a rare but potentially serious condition. Severe tracheobronchomalacia requires intervention or…”
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The behavioural response of mice lacking NK 1 receptors to guanfacine resembles its clinical profile in treatment of ADHD
Published in British journal of pharmacology (01-10-2014)“…Background and Purpose Mice with functional ablation of substance P ‐preferring neurokinin‐1 receptors ( NK1R −/− mice) display behavioural abnormalities…”
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A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
Published in The Lancet. Digital health (01-11-2023)“…Differentiating between self-resolving viral infections and bacterial infections in children who are febrile is a common challenge, causing difficulties in…”
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Relationship between molecular pathogen detection and clinical disease in febrile children across Europe: a multicentre, prospective observational study
Published in The Lancet regional health. Europe (01-09-2023)“…The PERFORM study aimed to understand causes of febrile childhood illness by comparing molecular pathogen detection with current clinical practice. Febrile…”
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Antagonism of L-type Cav channels with nifedipine differentially affects performance of wildtype and NK1R−/− mice in the 5-Choice Serial Reaction-Time Task
Published in Neuropharmacology (01-01-2013)“…Mice with functional ablation of the substance P-preferring receptor gene (‘Nk1r’ in mice (‘NK1R−/−’), ‘TACR1’ in humans) display deficits in cognitive…”
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Antagonism of L-type Ca(v) channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task
Published in Neuropharmacology (01-01-2013)“…Mice with functional ablation of the substance P-preferring receptor gene ('Nk1r' in mice ('NK1R-/-'), 'TACR1' in humans) display deficits in cognitive…”
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