Search Results - "Dudley, Atira"

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors by Jessen, Walter J, Miller, Shyra J, Jousma, Edwin, Wu, Jianqiang, Rizvi, Tilat A, Brundage, Meghan E, Eaves, David, Widemann, Brigitte, Kim, Mi-Ok, Dombi, Eva, Sabo, Jessica, Hardiman Dudley, Atira, Niwa-Kawakita, Michiko, Page, Grier P, Giovannini, Marco, Aronow, Bruce J, Cripe, Timothy P, Ratner, Nancy

“…Neurofibromatosis type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve…”
Get full text

MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells by Martis, Prithy C, Dudley, Atira T, Bemrose, Melissa A, Gazda, Hunter L, Smith, Barry H, Gazda, Lawrence S

“…Agarose encapsulated murine renal adenocarcinoma cells (RENCA macrobeads) are currently being investigated in clinical trials as a treatment for…”
Get full text

Abstract 2731: Checkpoint inhibitor therapy in combination with the implantation of agarose encapsulated cancer cells inhibits tumor growth in a mouse model of osteosarcoma by Dumpala, Pradeep R., Martis, Prithy C., Bemrose, Melissa A., Dudley, Atira, Smith, Barry H., Gazda, Lawrence S.

“…Abstract We have previously shown that murine renal adenocarcinoma (RENCA) cells encapsulated in agarose macrobeads (MB) secrete factors that inhibit the…”
Get full text

Abstract 1285: Regulation of docetaxel resistant cancer stem-like cells by RENCA macrobeads by Martis, Prithy Caroline, Dudley, Atira T., Dumpala, Pradeep R., Gazda, Hunter L., Bemrose, Melissa A., Smith, Barry H., Gazda, Lawrence S.

“…Abstract Despite the initial efficacy of chemotherapy, resistant cells often persist and are thought to contribute to disease relapse. Resistant cells,…”
Get full text

Abstract 3891: Chemoresistant cancer stem cells undergo gene changes that drive tumor recurrence by Martis, Prithy C., Dudley, Atira, Laramore, Melissa A., Gazda, Hunter L., Markey, Michael P., Smith, Barry H., Gazda, Lawrence S.

“…Abstract Despite the efficacy of chemotherapy, resistant cells are thought to contribute to tumor recurrence. In vitro models of recurrence must mimic the…”
Get full text

Abstract 5552: Differential proteomic responses of luminal-A and basal-like breast cancer cell lines during growth inhibition induced by co-culture with agarose encapsulated murine renal adenocarcinoma (RENCA) cells by Laramore, Melissa A., James, Peter, Martis, Prithy C., Dudley, Atira, Gazda, Lawrence S., Borrebaeck, Carl A., Smith, Barry H.

“…Abstract The existence of a tumor growth regulatory network that is conserved across tumor types and species has been hypothesized. Our evidence for this…”
Get full text

Abstract 1675: MEF2 plays a significant role in the tumor inhibitory effects of agarose encapsulated RENCA cells through the EGF receptor by Martis, Prithy C., Laramore, Melissa A., Dudley, Atira, Smith, Barry H., Gazda, Lawrence S.

“…Abstract Identification of the molecular targets involved in the tumor growth inhibition induced by agarose encapsulated mouse renal adenocarcinoma (RENCA)…”
Get full text

Abstract B36: RENCA macrobead-induced AKT hyperphosphorylation leads to MEF2 activation and inhibition of the proliferation of human DU145 prostate carcinoma cells by Martis, Prithy C., Laramore, Melissa A., Dudley, Atira T., Smith, Barry H., Gazda, Lawrence S.

“…Abstract We have previously reported that suppression of the isoforms of myocyte enhancer factor (MEF2) in target tumor cells in vitro reduces the demonstrated…”
Get full text

Abstract 4609: MEF2 plays a critical role in RENCA macrobead-induced tumor cell growth inhibition by Martis, Prithy C., Dudley, Atira, Laramore, Melissa A., Smith, Barry H., Gazda, Lawrence S.

“…Abstract Regulation of cell proliferation and cell death is often dependent on the coupling of extracellular signals to the activation or repression of…”
Get full text

Abstract 2486: Docetaxel resistant cells display cancer stem cell properties and regulate growth via PI3/Akt signaling by Martis, Prithy C., Laramore, Melissa A., Gazda, Hunter L., Dudley, Atira, Dumpala, Pradeep R., Ocean, Allyson J., Berman, Nathaniel, Parikh, Tapan, Andrada, Zoe P., Nazarian, Angelica, Thomas, Joanne, Akahoho, Eugene, Stoms, George, Yaroshinsky, Alex, Fahey, Thomas J., Wolf, David J., Gazda, Lawrence S., Smith, Barry H.

“…Abstract Both normal organogenesis and tumor development follow a Gompertzian growth curve. An understanding of the mechanisms operating in these apparently…”
Get full text

Treatment of agarose-agarose RENCA macrobeads with docetaxel selects for OCT4+ cells with tumor-initiating capability by Gazda, Lawrence S, Martis, Prithy C, Laramore, Melissa A, Bautista, Melissa A, Dudley, Atira, Vinerean, Horatiu V, Smith, Barry H

“…The cancer stem cell (CSC) theory depicts such cells as having the capacity to produce both identical CSCs (symmetrical division) and tumor-amplifying daughter…”
Get full text