Search Results - "Dudgeon, T"

Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution by Jones, E. Y, Harlos, K, Bottomley, M. J, Robinson, R. C, Driscoll, P. C, Edwards, R. M, Clements, J. M, Dudgeon, T. J, Stuart, D. I

“…The cell-surface glycoprotein vascular cell adhesion molecule-1 (VCAM-1; ref. 1) mediates intercellular adhesion by specific binding to the integrin very-late…”
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Identification of MMP-18, a Putative Novel Human Matrix Metalloproteinase by Cossins, J., Dudgeon, T.J., Catlin, G., Gearing, A.J.H., Clements, J.M.

“…A partial cDNA encoding the 3′ end of a putative novel human matrix metalloproteinase (MMP) was identified by sequence similarity searching of databases…”
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Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin by CLEMENTS, J. M, NEWHAM, P, SHEPHERD, M, GILBERT, R, DUDGEON, T. J, NEEDHAM, L. A, EDWARDS, R. M, BERRY, L, BRASS, A, HUMPHRIES, M. J

“…The integrin adhesion receptor alpha 4 beta 1 binds two ligands, the extracellular matrix glycoprotein fibronectin and the immunoglobulin superfamily member…”
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Chemical modification of a variant of human MIP-1α; implications for dimer structure by ASHFIELD, J.T., MEYERS, T., LOWNE, D., VARLEY, P.G., ARNOLD, J.R.P., TAN, P., YANG, J.-C., CZAPLEWSKI, L.G., DUDGEON, T., FISHER, J.

“…A sequence variant of human MIP-1α, in which Asp26 has been replaced by Ala, has been chemically modified by the addition of 13C-labeled methyl groups at each…”
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Structure-function analysis of epidermal growth factor: site directed mutagenesis and nuclear magnetic resonance by Dudgeon, T.J., Cooke, R.M., Baron, M., Campbell, I.D., Edwards, R.M., Fallon, A.

“…The role of leucine-47 in determining the structure and activity of human epidermal growth factor was examined using site-directed mutagenesis. Wild type…”
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Chemical modification of a variant of human MIP-1alpha; implications for dimer structure by Ashfield, J T, Meyers, T, Lowne, D, Varley, P G, Arnold, J R, Tan, P, Yang, J C, Czaplewski, L G, Dudgeon, T, Fisher, J

“…A sequence variant of human MIP-1alpha, in which Asp26 has been replaced by Al alpha, has been chemically modified by the addition of 13C-labeled methyl groups…”
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Time between presentation and treatment of six common cancers: a study in Devon by Jones, R V, Dudgeon, T A

“…The time between a person presenting to a general practitioner with a symptom of cancer and that person starting treatment has been studied in Devon…”
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Structure-function relationships in epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) by Campbell, I D, Baron, M, Cooke, R M, Dudgeon, T J, Fallon, A, Harvey, T S, Tappin, M J

“…The solution structures of the homologous growth factors human epidermal growth factor (hEGF) and human transforming growth factor-alpha (hTGF-alpha), as…”
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OpenRiskNet, an open e-infrastructure to support data sharing, knowledge integration and in silico analysis and modelling in risk assessment by Exner, T.E., Dokler, J., Bachler, D., Farcal, L.R., Evelo, C.T., Willighagen, E., Jennen, D.G.J., Jabocs, M., Doganis, P., Sarimveis, H., Lynch, I., Gkoutos, G., Kramer, S., Notredame, C., Spjuth, O., Jennings, P., Dudgeon, T., Bois, F., Hardy, B.

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Crystallization and preliminary X-ray diffraction characterisation of both a native and selenomethionyl VLA-4 binding fragment of VCAM-1 by Bottomley, M J, Robinson, R C, Driscoll, P C, Harlos, K, Stuart, D I, Aplin, R T, Clements, J M, Jones, E Y, Dudgeon, T J

“…Soluble fragments of the extracellular region of vascular cell adhesion molecule 1 (VCAM-1) expressed in Escherichia coli retain functional adhesive activity…”
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Structure-function relationships in human epidermal growth factor studied by site-directed mutagenesis and 1H NMR by HOMMEL, U, DUDGEON, T. J, FALLON, A, EDWARDS, R. M, CAMPBELL, I. D

“…In order to elucidate the mechanism of interaction between human epidermal growth factor (EGF) and its receptor, selected variants of EGF, differing by single…”
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The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor-like pair of modules of tissue-type plasminogen activator by Smith, Brian O, Downing, A.Kristina, Driscoll, Paul C, Dudgeon, Timothy J, Campbell, Iain D

“…Background: The thrombolytic serine protease tissue-type plasminogen activator (t-PA) is a classical modular protein consisting of three types of domain in…”
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Secondary Structure of Fibronectin Type 1 and Epidermal Growth Factor Modules from Tissue-Type Plasminogen Activator by Nuclear Magnetic Resonance by Smith, Brian O, Downing, A. Kristina, Dudgeon, Timothy J, Cunningham, Mark, Driscoll, Paul C, Campbell, Iain D

“…A segment of human tissue-type plasminogen activator (t-PA) corresponding to the fibronectin type 1 (F1) and epidermal growth factor-like (G) pair of modules,…”
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Identification of Amino Acid Residues Critical for Aggregation of Human CC Chemokines Macrophage Inflammatory Protein (MIP)-1 alpha , MIP-1 beta , and RANTES: Characterization of Active Disaggregated Chemokine Variants by Czaplewski, L G, McKeating, J, Craven, C J, Higgins, L D, Appay, V, Brown, A, Dudgeon, T, Howard, LA, Meyers, T, Owen, J, Palan, SR, Tan, P, Wilson, G, Woods, N R, Heyworth, C M, Lord, B I, Brotherton, D, Christison, R, Craig, S, Cribbes, S, Edwards, R M, Evans, S J, Gilbert, R, Morgan, P, Randle, E, Schofield, N, Varley, P G, Fisher, J, Waltho, J P, Hunter, M G

“…Human CC chemokines macrophage inflammatory protein (MIP)-1 alpha , MIP-1 beta , and RANTES (regulated on activation normal T cell expressed) self-associate to…”
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Selective cleavage of human IgG by the matrix metalloproteinases, matrilysin and stromelysin by Gearing, Andrew J.H, Thorpe, Susan J, Miller, Karen, Mangan, Matthew, Varley, Paul G, Dudgeon, Tim, Ward, George, Turner, Christina, Thorpe, Robin

“…We have shown that two of the matrix metalloproteinases (MMPs), matrilysin and stromelysin-1, are capable of cleaving all of the human IgG subclasses. The…”
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Keyed Bugle by Dudgeon, Ralph T.

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Expression and Characterization of a Very‐Late Antigen‐4 (α4β1) Integrin‐Binding Fragment of Vascular Cell‐Adhesion Molecule‐1 by Dudgeon, Timothy J., Bottomley, Matthew J., Driscoll, Paul C., Humphries, Martin J., Mould, A. Paul, Wingfield, George I., Clements, John M.

“…We have used an Escherichia coli expression system to produce forms of vascular cell‐adhesion molecule‐1 (VCAM‐1) containing the first two and three supposed…”
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A Question of Balance: Charles Seeger's Philosophy of Music by Dudgeon, Ralph T.

“…Dudgeon reviews "A Question of Balance: Charles Seeger's Philosophy of Music" by Taylor Aitken Greer…”
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For the record: Chemical modification of a variant of human MIP‐1α; implications for dimer structure by Ashfield, J. T., Fisher, J., Meyers, T., Lowne, D., Czaplewski, L. G., Dudgeon, T., Varley, P. G., Arnold, J. R. P., Tan, P., Yang, J.‐C.

“…A sequence variant of human MIP‐1α, in which Asp26 has been replaced by Ala, has been chemically modified by the addition of 13C‐labeled methyl groups at each…”
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Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants by Czaplewski, L G, McKeating, J, Craven, C J, Higgins, L D, Appay, V, Brown, A, Dudgeon, T, Howard, L A, Meyers, T, Owen, J, Palan, S R, Tan, P, Wilson, G, Woods, N R, Heyworth, C M, Lord, B I, Brotherton, D, Christison, R, Craig, S, Cribbes, S, Edwards, R M, Evans, S J, Gilbert, R, Morgan, P, Randle, E, Schofield, N, Varley, P G, Fisher, J, Waltho, J P, Hunter, M G

“…Human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on activation normal T cell expressed) self-associate to…”
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