Search Results - "Dudek, Hanna M."
-
1
Mapping the Substrate Binding Site of Phenylacetone Monooxygenase from Thermobifida fusca by Mutational Analysis
Published in Applied and Environmental Microbiology (15-08-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
2
Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca
Published in Applied microbiology and biotechnology (01-11-2010)“…Type I Baeyer-Villiger monooxygenases (BVMOs) strongly prefer NADPH over NADH as an electron donor. In order to elucidate the molecular basis for this coenzyme…”
Get full text
Journal Article -
3
Beyond the Protein Matrix: Probing Cofactor Variants in a Baeyer–Villiger Oxygenation Reaction
Published in ACS catalysis (06-12-2013)“…A general question in biochemistry is the interplay between the chemical properties of cofactors and the surrounding protein matrix. Here, the functions of…”
Get full text
Journal Article -
4
A stepwise approach for the reproducible optimization of PAMO expression in Escherichia coli for whole-cell biocatalysis
Published in BMC biotechnology (21-06-2012)“…Baeyer-Villiger monooxygenases (BVMOs) represent a group of enzymes of considerable biotechnological relevance as illustrated by their growing use as…”
Get full text
Journal Article -
5
Baeyer–Villiger monooxygenases: recent advances and future challenges
Published in Current opinion in chemical biology (01-04-2010)“…Baeyer–Villiger monooxygenases For many enzyme classes, a wealth of information on, for example, structure and mechanism has been generated in the last few…”
Get full text
Journal Article -
6
Snapshots of enzymatic Baeyer-Villiger catalysis: oxygen activation and intermediate stabilization
Published in The Journal of biological chemistry (19-08-2011)“…Baeyer-Villiger monooxygenases catalyze the oxidation of carbonylic substrates to ester or lactone products using NADPH as electron donor and molecular oxygen…”
Get full text
Journal Article -
7
Metal Dependence of the Xylose Isomerase from Piromyces sp. E2 Explored by Activity Profiling and Protein Crystallography
Published in Biochemistry (Easton) (14-11-2017)“…Xylose isomerase from Piromyces sp. E2 (PirXI) can be used to equip Saccharomyces cerevisiae with the capacity to ferment xylose to ethanol. The biochemical…”
Get full text
Journal Article -
8
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates
Published in Journal of the American Chemical Society (18-01-2017)“…Regio- and stereoselective Baeyer–Villiger oxidations are difficult to achieve by classical chemical means, particularly when large, functionalized molecules…”
Get full text
Journal Article -
9
Finding the Switch: Turning a Baeyer–Villiger Monooxygenase into a NADPH Oxidase
Published in Journal of the American Chemical Society (10-12-2014)“…By a targeted enzyme engineering approach, we were able to create an efficient NADPH oxidase from a monooxygenase. Intriguingly, replacement of only one…”
Get full text
Journal Article -
10
Extending the substrate scope of a Baeyer–Villiger monooxygenase by multiple-site mutagenesis
Published in Applied microbiology and biotechnology (01-05-2014)“…Baeyer–Villiger monooxygenase-catalysed reactions are attractive for industrial processes. Here we report on expanding the substrate scope of phenylacetone…”
Get full text
Journal Article -
11
Chemoenzymatic approaches to obtain chiral-centered selenium compounds
Published in Tetrahedron (23-12-2012)“…The synthesis of chiral-centered selenium compounds is presented. Enantioselective oxidations of these organoselenium compounds were performed using a wide…”
Get full text
Journal Article -
12
A generic, whole-cell-based screening method for Baeyer-Villiger monooxygenases
Published in Journal of biomolecular screening (01-07-2013)“…Baeyer-Villiger monooxygenases (BVMOs) have been receiving increasing attention as enzymes useful for biocatalytic applications. Industrial requirements call…”
Get more information
Journal Article -
13
Snapshots of Enzymatic Baeyer-Villiger Catalysis
Published in The Journal of biological chemistry (01-08-2011)“…Baeyer-Villiger monooxygenases catalyze the oxidation of carbonylic substrates to ester or lactone products using NADPH as electron donor and molecular oxygen…”
Get full text
Journal Article -
14
Chemoenzymatic approaches to obtain chiral-centered selenium compounds: Progress in Organoselenium and Organotellurium Chemistry
Published in Tetrahedron (2012)Get full text
Journal Article