Search Results - "Dudek, Aleksandra M"

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death by Garg, Abhishek D, Dudek, Aleksandra M, Ferreira, Gabriela B, Verfaillie, Tom, Vandenabeele, Peter, Krysko, Dmitri V, Mathieu, Chantal, Agostinis, Patrizia

“…Calreticulin surface exposure (ecto-CALR), ATP secretion, maturation of dendritic cells (DCs) and stimulation of T cells are prerequisites for anticancer…”
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Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin by Dudek-Perić, Aleksandra M, Ferreira, Gabriela B, Muchowicz, Angelika, Wouters, Jasper, Prada, Nicole, Martin, Shaun, Kiviluoto, Santeri, Winiarska, Magdalena, Boon, Louis, Mathieu, Chantal, van den Oord, Joost, Stas, Marguerite, Gougeon, Marie-Lise, Golab, Jakub, Garg, Abhishek D, Agostinis, Patrizia

“…Systemic chemotherapy generally has been considered immunosuppressive, but it has become evident that certain chemotherapeutic drugs elicit immunogenic danger…”
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LINC00857 expression predicts and mediates the response to platinum‐based chemotherapy in muscle‐invasive bladder cancer by Dudek, Aleksandra M., Kampen, Jasmijn G. M., Witjes, J. Alfred, Kiemeney, Lambertus A. L. M., Verhaegh, Gerald W.

“…Approximately 20% of patients with bladder cancer are diagnosed with muscle‐invasive disease (MIBC). The treatment involves radical cystectomy, but almost 50%…”
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Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity by Garg, Abhishek D, Dudek, Aleksandra M, Agostinis, Patrizia

“…The inspection of the mechanisms through which autophagy modulates immunogenic cell death revealed that the autophagic response of cancer cells to reactive…”
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An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAFV600E inhibitor-resistant metastatic melanoma cells by Martin, Shaun, Dudek-Peric, Aleksandra M., Garg, Abhishek D., Roose, Heleen, Demirsoy, Seyma, Van Eygen, Sofie, Mertens, Freya, Vangheluwe, Peter, Vankelecom, Hugo, Agostinis, Patrizia

“…The ingrained capacity of melanoma cells to rapidly evolve toward an aggressive phenotype is manifested by their increased ability to develop drug-resistance,…”
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Molecular Phenotyping of AR Signaling for Predicting Targeted Therapy in Castration Resistant Prostate Cancer by Hamid, Agus Rizal A. H., Luna-Velez, Maria V., Dudek, Aleksandra M., Jansen, Cornelius F. J., Smit, Frank, Aalders, Tilly W., Verhaegh, Gerald W., Schaafsma, Ewout, Sedelaar, John P. M., Schalken, Jack A.

“…Castration-resistant prostate cancer (CRPC) is defined by resistance of the tumor to androgen deprivation therapy (ADT). Several molecular changes,…”
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Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity by Dudek, Aleksandra M, Martin, Shaun, Garg, Abhishek D, Agostinis, Patrizia

“…Dendritic cells (DCs) are the sentinel antigen-presenting cells of the immune system; such that their productive interface with the dying cancer cells is…”
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Prognostic relevance of urinary bladder cancer susceptibility loci by Grotenhuis, Anne J, Dudek, Aleksandra M, Verhaegh, Gerald W, Witjes, J Alfred, Aben, Katja K, van der Marel, Saskia L, Vermeulen, Sita H, Kiemeney, Lambertus A

“…In the last few years, susceptibility loci have been identified for urinary bladder cancer (UBC) through candidate-gene and genome-wide association studies…”
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Urinary bladder cancer susceptibility markers. What do we know about functional mechanisms? by Dudek, Aleksandra M, Grotenhuis, Anne J, Vermeulen, Sita H, Kiemeney, Lambertus A L M, Verhaegh, Gerald W

“…Genome-wide association studies (GWAS) have been successful in the identification of the several urinary bladder cancer (UBC) susceptibility loci, pointing…”
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Inducers of immunogenic cancer cell death by Dudek, Aleksandra M, Garg, Abhishek D, Krysko, Dmitri V, De Ruysscher, Dirk, Agostinis, Patrizia

“…Abstract Recently, cytokine-based pro-tumourigenic signalling has been found to play a major role in the immune system's pro-tumourigenic activity. On the…”
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Cancer immunogenicity, danger signals, and DAMPs: What, when, and how? by Garg, Abhishek D., Dudek, Aleksandra M., Agostinis, Patrizia

“…Cancer immunosurvelliance usually leads to formation of cancer cells that have been “immunoedited” to resist anti‐tumor immunity. One of the consequences of…”
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Immunogenic cell death by Garg, Abhishek D, Dudek-Peric, Aleksandra M, Romano, Erminia, Agostinis, Patrizia

“…Currently, it is widely acknowledged that a proactive anticancer immunosurveillance mechanism takes part in the rejection of neoplastic lesions before they…”
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Identification of long non-coding RNAs that stimulate cell survival in bladder cancer by Dudek, Aleksandra M, Boer, Sabrina J, Boon, Nanda, Witjes, J Alfred, Kiemeney, Lambertus A L M, Verhaegh, Gerald W

“…For many years, research on the biology underlying bladder cancer focused on protein-coding genes which cover only about 3% of the human genome. Recently, it…”
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Identification of an enhancer region within the TP63/LEPREL1 locus containing genetic variants associated with bladder cancer risk by Dudek, Aleksandra M., Vermeulen, Sita H., Kolev, Dimitar, Grotenhuis, Anne J., Kiemeney, Lambertus A. L. M., Verhaegh, Gerald W.

“…Purpose Genome-wide association studies (GWAS) have led to the identification of a bladder cancer susceptibility variant (rs710521) in a non-coding intergenic…”
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Melphalan, Antimelanoma Immunity, and Inflammation--Response by Garg, Abhishek D, Dudek-Peric, Aleksandra M, Agostinis, Patrizia

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An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAF V600E inhibitor-resistant metastatic melanoma cells by Martin, Shaun, Dudek-Peric, Aleksandra M, Garg, Abhishek D, Roose, Heleen, Demirsoy, Seyma, Van Eygen, Sofie, Mertens, Freya, Vangheluwe, Peter, Vankelecom, Hugo, Agostinis, Patrizia

“…The ingrained capacity of melanoma cells to rapidly evolve toward an aggressive phenotype is manifested by their increased ability to develop drug-resistance,…”
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Melanoma immunotherapy by Garg, Abhishek D, Dudek-Peric, Aleksandra M, Agostinis, Patrizia

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Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death by Garg, Abhishek D, Galluzzi, Lorenzo, Apetoh, Lionel, Baert, Thais, Birge, Raymond B, Bravo-San Pedro, José Manuel, Breckpot, Karine, Brough, David, Chaurio, Ricardo, Cirone, Mara, Coosemans, An, Coulie, Pierre G, De Ruysscher, Dirk, Dini, Luciana, de Witte, Peter, Dudek-Peric, Aleksandra M, Faggioni, Alberto, Fucikova, Jitka, Gaipl, Udo S, Golab, Jakub, Gougeon, Marie-Lise, Hamblin, Michael R, Hemminki, Akseli, Herrmann, Martin, Hodge, James W, Kepp, Oliver, Kroemer, Guido, Krysko, Dmitri V, Land, Walter G, Madeo, Frank, Manfredi, Angelo A, Mattarollo, Stephen R, Maueroder, Christian, Merendino, Nicolò, Multhoff, Gabriele, Pabst, Thomas, Ricci, Jean-Ehrland, Riganti, Chiara, Romano, Erminia, Rufo, Nicole, Smyth, Mark J, Sonnemann, Jürgen, Spisek, Radek, Stagg, John, Vacchelli, Erika, Vandenabeele, Peter, Vandenberk, Lien, Van den Eynde, Benoit J, Van Gool, Stefaan, Velotti, Francesca, Zitvogel, Laurence, Agostinis, Patrizia

“…The immunogenicity of malignant cells has recently been acknowledged as a critical determinant of efficacy in cancer therapy. Thus, besides developing direct…”
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Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer by Rafnar, Thorunn, Sulem, Patrick, Thorleifsson, Gudmar, Vermeulen, Sita H, Helgason, Hannes, Saemundsdottir, Jona, Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Stacey, Simon N, Gudmundsson, Julius, Johannsdottir, Hrefna, Alexiusdottir, Kristin, Petursdottir, Vigdis, Nikulasson, Sigfus, Geirsson, Gudmundur, Jonsson, Thorvaldur, Aben, Katja K H, Grotenhuis, Anne J, Verhaegh, Gerald W, Dudek, Aleksandra M, Witjes, J Alfred, van der Heijden, Antoine G, Vrieling, Alina, Galesloot, Tessel E, De Juan, Ana, Panadero, Angeles, Rivera, Fernando, Hurst, Carolyn, Bishop, D Timothy, Sak, Sei C, Choudhury, Ananya, Teo, Mark T W, Arici, Cecilia, Carta, Angela, Toninelli, Elena, de Verdier, Petra, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, van der Keur, Kirstin A, Lurkin, Irene, Goossens, Mieke, Kellen, Eliane, Guarrera, Simonetta, Russo, Alessia, Critelli, Rossana, Sacerdote, Carlotta, Vineis, Paolo, Krucker, Clémentine, Zeegers, Maurice P, Gerullis, Holger, Ovsiannikov, Daniel, Volkert, Frank, Hengstler, Jan G, Selinski, Silvia, Magnusson, Olafur T, Masson, Gisli, Kong, Augustine, Gudbjartsson, Daniel, Lindblom, Annika, Zwarthoff, Ellen, Porru, Stefano, Golka, Klaus, Buntinx, Frank, Matullo, Giuseppe, Kumar, Rajiv, Mayordomo, José I, Steineck, D Gunnar, Kiltie, Anne E, Jonsson, Eirikur, Radvanyi, François, Knowles, Margaret A, Thorsteinsdottir, Unnur, Kiemeney, Lambertus A, Stefansson, Kari

“…Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded common variants at 12 loci that associate with risk of the disease. We…”
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LINC 00857 expression predicts and mediates the response to platinum‐based chemotherapy in muscle‐invasive bladder cancer by Dudek, Aleksandra M., van Kampen, Jasmijn G. M., Witjes, J. Alfred, Kiemeney, Lambertus A. L. M., Verhaegh, Gerald W.

“…Abstract Approximately 20% of patients with bladder cancer are diagnosed with muscle‐invasive disease ( MIBC ). The treatment involves radical cystectomy, but…”
Get full text