Search Results - "Dudeja, V."

Cathepsin B inhibition in the pancreatic stellate cells stimulates CD8+ T cell dependent anti-tumor immune response by Garg, Bharti, Jain, T., Vaish, U., Dudeja, V.

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Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of the phosphatidylinositol 3-kinase (PI3K) signaling pathway by Phillips, P.A, Sangwan, V, Borja-Cacho, D, Dudeja, V, Vickers, S.M, Saluja, A.K

“…Abstract Pancreatic cancer is the fourth leading cause of cancer related deaths and is a disease with poor prognosis. It is refractory to standard…”
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Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice by Sharif, R, Dawra, R, Wasiluk, K, Phillips, P, Dudeja, V, Kurt-Jones, E, Finberg, R, Saluja, A

“…Acute pancreatitis is an inflammatory disease involving acinar cell injury, and the rapid production and release of inflammatory cytokines, which play a…”
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Chronic pancreatitis in a caerulein-induced mouse model is associated with an altered gut microbiome by Tao, J., Cheema, H., Kesh, K., Dudeja, V., Dawra, R., Roy, S.

“…Chronic pancreatitis (CP) is an inflammatory disease of the pancreas with loss of exocrine/endocrine functions as well as development of fibrosis. Dysbiosis of…”
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Hypoxia mediated L-2-Hydroxyglutarate accumulation drive tumor growth by suppressing Anti-tumor immunity in Pancreatic Cancer by Gupta, V., Sharma, N., Garrido, V., Durden, B., Kesh, K., Edwards, D., Dudeja, V., Singh, P., Saluja, A., Banerjee, S.

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The role of heat shock proteins in gastrointestinal diseases by Dudeja, V, Vickers, S M, Saluja, A K

“…Heat shock proteins (HSPs) are a highly conserved family of proteins which inhabit almost all subcellular locations and cellular membranes. Depending on their…”
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Molecular targeted approaches for treatment of pancreatic cancer by Huang, Z Q, Saluja, A K, Dudeja, V, Vickers, S M, Buchsbaum, D J

“…Human pancreatic cancer remains a highly malignant disease with almost similar incidence and mortality despite extensive research. Many targeted therapies are…”
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BMI does not accurately predict overweight in Asian Indians in northern India by Dudeja, V., Misra, A., Pandey, R.M., Devina, G., Kumar, G., Vikram, N.K.

“…Asian Indians are at high risk for the development of atherosclerosis and related complications, possibly initiated by higher body fat (BF). The present study…”
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Increased nuclear transport of β catenin and LRP 6 phosphorylation as novel prognostic biomarkers for the progression of pancreatic tumor by Garg, B, Modi, S, Majumder, K, Banerjee, S, Dudeja, V, Saluja, A

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The role of the unfolded protein response in chemoresistance and cell death by Dauer, P, McGinn, O, Zhao, X, Arora, N, Singh, M, Dudeja, V, Banerjee, S, Saluja, A

“…Additionally, the KPC tumors have increased GRP78 expression in the ducts as tumors progress from pre-cancerous lesions to pancreatic adenocarcinoma, detected…”
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JAK-2 Downregulation Sensitizes Pancreatic Cancer Cells to TRAIL Induced Cell Death by Augmenting Death Induced Signaling Complex Formation by Dudeja, V, Oliveira, A, Banerjee, S, Sangwan, V, Mujumdar, N, MacKenzie, T.N, Dawra, R, Vickers, S.M, Saluja, A.K

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Triptolide enriches for CD133+ “stem-like” tumor initiating cells in pancreatic cancer by Banerjee, S, Nomura, A, Mujumdar, N, Dudeja, V, Sangwan, V, Vickers, S.M, Saluja, A

“…Both 12T and CSM cells formed progressive subcutaneous tumors in mice indicating that these cells had tumor initiating properties. 12T cells and CSM cells were…”
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Triptolide induces cell death in pancreatic cancer through glycosylation of the transcription factor Sp1 by Banerjee, S, Sangwan, V, McGinn, O, Mujumdar, N, Dudeja, V, Chen, Z, Mackenzie, T, Vickers, S.M, Saluja, A

“…Background: Sp1 protein is a sequence-specific, DNA-binding protein that is a part of the Specificity protein/Kruppel-like factor family of transcription…”
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Triptolide enriches for CD133+ “stem-like” tumor initiating cells in pancreatic cancer by Banerjee, S, Nomura, A, Mujumdar, N, Dudeja, V, Sangwan, V, Vickers, S.M, Saluja, A

“…Both 12T and CSM cells formed progressive subcutaneous tumors in mice indicating that these cells had tumor initiating properties. 12T cells and CSM cells were…”
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Combination of TRAIL and JAK-2 Downregulation: Novel Therapeutic Strategy Against Pancreatic Cancer by Dudeja, V, Skube, S.J, Beyer, G, Banerjee, S, Sangwan, V, Dawra, R, Vickers, S.M, Saluja, A.K

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MicroRNA-142-3p, a novel regulator of heat shock protein 70, modulates triptolide-induced pancreatic cancer cell death by MacKenzie, T.N, Sangwan, V, Mujumdar, N, Banerjee, S, Dudeja, V, Subramanian, S, Vickers, S, Saluja, A.K

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Pancreatic cancer care quality measures in rural Americans by Chow, C.J, Habermann, E.B, Zhu, Y, Abraham, A, Dudeja, V, Vickers, S.M, Al-Refaie, W.B

“…Controlling for covariates, multivariate regression explored the impact of rurality on stage at diagnosis, undergoing pancreatectomy for operable disease and…”
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Triptolide causes apoptosis in cancer cells derived from both primary tumor and liver metastasis in a spontaneous pancreatic cancer mouse model by Sangwan, V, Chugh, R, Dudeja, V, Chen, Z, Dawra, R.K, Mujumdar, N, Banerjee, S, Mackenzie, T, Krosch, T.C, Vickers, S, Saluja, A.K

“…Results: The ability of various pancreatic cancer cell lines (MIAPaCa-2, AsPC-1, S2-013, S2-VP10, KPC, LM) to form tumors was assessed by subcutaneous tumor…”
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JAK-2 downregulation sensitizes pancreatic cancer cells to TRAIL induced cell death by Dudeja, V, Oliveira, A, Banerjee, S, Sangwan, V, Mujumdar, N, MacKenzie, T.N, Dawra, R.K, Vickers, S.M, Saluja, A.K

“…Conclusion: Inhibition of JAK-2 pathway sensitizes pancreatic cancer cells to TRAIL induced apoptosis and cell death through increased formation of DISC…”
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Triptolide causes global changes in the microRNAome and transcriptome of pancreatic cancer cells by MacKenzie, T.N, Sarver, A, Chen, Z, Mujumdar, N, Banerjee, S, Sangwan, V, Dudeja, V, Subramanian, S, Vickers, S, Saluja, A.K

“…Methods: We performed miRNA and mRNA microarray analysis of human pancreatic cancer cells (MiaPaCa-2 and S2-013) prior to and following different time points…”
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