Search Results - "Duddy, William J"

Age-Associated Methylation Suppresses SPRY1, Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle by Bigot, Anne, Duddy, William J., Ouandaogo, Zamalou G., Negroni, Elisa, Mariot, Virginie, Ghimbovschi, Svetlana, Harmon, Brennan, Wielgosik, Aurore, Loiseau, Camille, Devaney, Joe, Dumonceaux, Julie, Butler-Browne, Gillian, Mouly, Vincent, Duguez, Stéphanie

“…The molecular mechanisms by which aging affects stem cell number and function are poorly understood. Murine data have implicated cellular senescence in the…”
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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles by Le Gall, Laura, Duddy, William J., Martinat, Cecile, Mariot, Virginie, Connolly, Owen, Milla, Vanessa, Anakor, Ekene, Ouandaogo, Zamalou G., Millecamps, Stephanie, Lainé, Jeanne, Vijayakumar, Udaya Geetha, Knoblach, Susan, Raoul, Cedric, Lucas, Olivier, Loeffler, Jean Philippe, Bede, Peter, Behin, Anthony, Blasco, Helene, Bruneteau, Gaelle, Del Mar Amador, Maria, Devos, David, Henriques, Alexandre, Hesters, Adele, Lacomblez, Lucette, Laforet, Pascal, Langlet, Timothee, Leblanc, Pascal, Le Forestier, Nadine, Maisonobe, Thierry, Meininger, Vincent, Robelin, Laura, Salachas, Francois, Stojkovic, Tanya, Querin, Giorgia, Dumonceaux, Julie, Butler Browne, Gillian, González De Aguilar, Jose‐Luis, Duguez, Stephanie, Pradat, Pierre Francois

“…Background The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought…”
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MyoMiner: explore gene co-expression in normal and pathological muscle by Malatras, Apostolos, Michalopoulos, Ioannis, Duguez, Stéphanie, Butler-Browne, Gillian, Spuler, Simone, Duddy, William J

“…High-throughput transcriptomics measures mRNA levels for thousands of genes in a biological sample. Most gene expression studies aim to identify genes that are…”
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Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment by Parker, Maura H., Loretz, Carol, Tyler, Ashlee E., Duddy, William J., Hall, John K., Olwin, Bradley B., Bernstein, Irwin D., Storb, Rainer, Tapscott, Stephen J.

“…Transplantation of myogenic stem cells possesses great potential for long‐term repair of dystrophic muscle. However, a single donor muscle biopsy is unlikely…”
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Arabidopsis Coexpression Tool: a tool for gene coexpression analysis in Arabidopsis thaliana by Zogopoulos, Vasileios L., Saxami, Georgia, Malatras, Apostolos, Angelopoulou, Antonia, Jen, Chih-Hung, Duddy, William J., Daras, Gerasimos, Hatzopoulos, Polydefkis, Westhead, David R., Michalopoulos, Ioannis

“…Gene coexpression analysis refers to the discovery of sets of genes which exhibit similar expression patterns across multiple transcriptomic data sets, such as…”
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Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation by Duguez, Stephanie, Duddy, William J, Gnocchi, Viola, Bowe, James, Dadgar, Sherry, Partridge, Terence A

“…Mitochondrial activity inhibits proliferation and is required for differentiation of myoblasts. Myoblast proliferation is also inhibited by the ~20% oxygen…”
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HGCA2.0: An RNA-Seq Based Webtool for Gene Coexpression Analysis in Homo sapiens by Zogopoulos, Vasileios L, Malatras, Apostolos, Kyriakidis, Konstantinos, Charalampous, Chrysanthi, Makrygianni, Evanthia A, Duguez, Stéphanie, Koutsi, Marianna A, Pouliou, Marialena, Vasileiou, Christos, Duddy, William J, Agelopoulos, Marios, Chrousos, George P, Iconomidou, Vassiliki A, Michalopoulos, Ioannis

“…Genes with similar expression patterns in a set of diverse samples may be considered coexpressed. Human Gene Coexpression Analysis 2.0 (HGCA2.0) is a webtool…”
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Molecular and Cellular Mechanisms Affected in ALS by Gall, Laura Le, Anakor, Ekene, Connolly, Owen, Vijayakumar, Udaya Geetha, Duddy, William J, Duguez, Stephanie

“…Amyotrophic lateral sclerosis (ALS) is a terminal late-onset condition characterized by the loss of upper and lower motor neurons. Mutations in more than 30…”
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A Systematic Review of Genotype–Phenotype Correlation across Cohorts Having Causal Mutations of Different Genes in ALS by Connolly, Owen, Gall, Laura Le, McCluskey, Gavin, Donaghy, Colette G, Duddy, William J, Duguez, Stephanie

“…Amyotrophic lateral sclerosis is a rare and fatal neurodegenerative disease characterised by progressive deterioration of upper and lower motor neurons that…”
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Understanding Neuromuscular Health and Disease: Advances in Genetics, Omics, and Molecular Function by Duddy, William J., Duguez, Stephanie

“…The field of neuromuscular research has seen considerable recent advances in the molecular and cellular understanding of muscle biology, and the treatment of…”
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Recurring main-chain anion-binding motifs in short polypeptides: nests by Milner-White, E. James, Nissink, J. Willem M., Allen, Frank H., Duddy, William J.

“…A novel tripeptide motif called a nest has recently been described in proteins with the function of binding anionic, or partially anionic, atoms such as…”
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The isolated muscle fibre as a model of disuse atrophy: Characterization using PhAct, a method to quantify f-actin by Duddy, William J., Cohen, Tatiana, Duguez, Stephanie, Partridge, Terence A.

“…Research into muscle atrophy and hypertrophy is hampered by limitations of the available experimental models. Interpretation of in vivo experiments is…”
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Mimicry by asx‐ and ST‐turns of the four main types of β‐turn in proteins by Duddy, William J., Nissink, J. Willem M., Allen, Frank H., Milner‐White, E. James

“…Hydrogen‐bonded β‐turns in proteins occur in four categories: type I (the most common), type II, type II', and type I'. Asx‐turns resemble β‐turns, in that…”
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HGCA2.0: An RNA-Seq Based Webtool for Gene Coexpression Analysis in IHomo sapiens/I by Zogopoulos, Vasileios L, Malatras, Apostolos, Kyriakidis, Konstantinos, Charalampous, Chrysanthi, Makrygianni, Evanthia A, Duguez, Stéphanie, Koutsi, Marianna A, Pouliou, Marialena, Vasileiou, Christos, Duddy, William J, Agelopoulos, Marios, Chrousos, George P, Iconomidou, Vassiliki A, Michalopoulos, Ioannis

“…Genes with similar expression patterns in a set of diverse samples may be considered coexpressed. Human Gene Coexpression Analysis 2.0 (HGCA2.0) is a webtool…”
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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles by Le Gall, Laura, Duddy, William J, Martinat, Cecile, Mariot, Virginie, Connolly, Owen, Milla, Vanessa, Anakor, Ekene, Ouandaogo, Zamalou G, Millecamps, Stephanie, Lainé, Jeanne, Vijayakumar, Udaya Geetha, Knoblach, Susan, Raoul, Cédric, Lucas, Olivier, Loeffler, Jean Philippe, Bede, Peter, Behin, Anthony, Blasco, Helene, Bruneteau, Gaelle, del Mar Amador, Maria, Devos, David, Henriques, Alexandre, Hesters, Adele, Lacomblez, Lucette, Laforet, Pascal, Langlet, Timothee, Leblanc, Pascal, Le Forestier, Nadine, Maisonobe, Thierry, Meininger, Vincent, Robelin, Laura, Salachas, Francois, Stojkovic, Tanya, Querin, Giorgia, Dumonceaux, Julie, Butler Browne, Gillian, González de Aguilar, Jose‐luis, Duguez, Stephanie, Pradat, Pierre Francois

“…Background: The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought…”
Get full text