Search Results - "Duda, G N"

A biomaterial with a channel-like pore architecture induces endochondral healing of bone defects by Petersen, A., Princ, A., Korus, G., Ellinghaus, A., Leemhuis, H., Herrera, A., Klaumünzer, A., Schreivogel, S., Woloszyk, A., Schmidt-Bleek, K., Geissler, S., Heschel, I., Duda, G. N.

“…Biomaterials developed to treat bone defects have classically focused on bone healing via direct, intramembranous ossification. In contrast, most bones in our…”
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Muscle and tendon adaptation in adolescent athletes: A longitudinal study by Mersmann, F., Bohm, S., Schroll, A., Boeth, H., Duda, G. N., Arampatzis, A.

“…There is evidence that a non‐uniform adaptation of muscle and tendon in young athletes results in increased tendon stress during mid‐adolescence. The present…”
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Increased unilateral tendon stiffness and its effect on gait 2-6 years after Achilles tendon rupture by Agres, A. N., Duda, G. N., Gehlen, T. J., Arampatzis, A., Taylor, W. R., Manegold, S.

“…Achilles tendon rupture (ATR) alters tissue composition, which may affect long‐term tendon mechanics and ankle function during movement. However, a…”
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Influences of age and mechanical stability on volume, microstructure, and mineralization of the fracture callus during bone healing: Is osteoclast activity the key to age-related impaired healing? by Mehta, M, Strube, P, Peters, A, Perka, C, Hutmacher, D, Fratzl, P, Duda, G.N

“…Abstract Earlier studies have shown that the influence of fixation stability on bone healing diminishes with advanced age. The goal of this study was to…”
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Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing by Manjubala, I, Liu, Y, Epari, D.R, Roschger, P, Schell, H, Fratzl, P, Duda, G.N

“…Abstract After bone fracture, various cellular activities lead to the formation of different tissue types, which form the basis for the process of secondary…”
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CD73 and CD29 concurrently mediate the mechanically induced decrease of migratory capacity of mesenchymal stromal cells by Ode, A, Kopf, J, Kurtz, A, Schmidt-Bleek, K, Schrade, P, Kolar, P, Buttgereit, F, Lehmann, K, Hutmacher, D W, Duda, G N, Kasper, G

“…e assumption that mesenchymal stromal cell (MSC)-based-therapies are capable of augmenting physiological regeneration processes has fostered intensive basic…”
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The specialist in regeneration—the Axolotl—a suitable model to study bone healing? by Polikarpova, A., Ellinghaus, A., Schmidt-Bleek, O., Grosser, L., Bucher, C. H., Duda, G. N., Tanaka, E. M., Schmidt-Bleek, K.

“…While the axolotl’s ability to completely regenerate amputated limbs is well known and studied, the mechanism of axolotl bone fracture healing remains poorly…”
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Hip contact forces and gait patterns from routine activities by Bergmann, G, Deuretzbacher, G, Heller, M, Graichen, F, Rohlmann, A, Strauss, J, Duda, G.N

“…In vivo loads acting at the hip joint have so far only been measured in few patients and without detailed documentation of gait data. Such information is…”
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Determination of muscle loading at the hip joint for use in pre-clinical testing by Heller, M.O., Bergmann, G., Kassi, J.-P., Claes, L., Haas, N.P., Duda, G.N.

“…The stability of joint endoprostheses depends on the loading conditions to which the implant-bone complex is exposed. Due to a lack of appropriate muscle force…”
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Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia by El Khassawna, T, Toben, D, Kolanczyk, M, Schmidt-Bleek, K, Koennecke, I, Schell, H, Mundlos, S, Duda, G.N

“…Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease resulting from inactivating mutations in the gene encoding the protein…”
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CD73/5'-ecto-nucleotidase acts as a regulatory factor in osteo-/chondrogenic differentiation of mechanically stimulated mesenchymal stromal cells by Ode, A, Schoon, J, Kurtz, A, Gaetjen, M, Ode, J E, Geissler, S, Duda, G N

“…Bone regeneration is influenced by mesenchymal stromal cells (MSCs) and mechanical conditions. How healing outcome and mechanical stability are linked on the…”
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Proximal humeral fractures: how stiff should an implant be? A comparative mechanical study with new implants in human specimens by LILL, H, HEPP, P, KORNER, J, KASSI, J.-P, VERHEYDEN, A. P, JOSTEN, C, DUDA, G. N

“…The objective of this study was to determine the in vitro characteristics of the clinically used and newly developed implants for the stabilization of proximal…”
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A review of biomaterials in bone defect healing, remaining shortcomings and future opportunities for bone tissue engineering: The unsolved challenge by Winkler, T, Sass, F A, Duda, G N, Schmidt-Bleek, K

“…Despite its intrinsic ability to regenerate form and function after injury, bone tissue can be challenged by a multitude of pathological conditions. While…”
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The course of bone healing is influenced by the initial shear fixation stability by Schell, H., Epari, D.R., Kassi, J.P., Bragulla, H., Bail, H.J., Duda, G.N.

“…Fracture healing is influenced by fixation stability and experimental evidence suggests that the initial mechanical conditions may determine the healing…”
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Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model by Schwarzer, R, Nickel, N, Godau, J, Willie, B M, Duda, G N, Schwarzer, R, Cirovic, B, Leutz, A, Manz, R, Bogen, B, Dörken, B, Jundt, F

“…Despite evidence that deregulated Notch signalling is a master regulator of multiple myeloma (MM) pathogenesis, its contribution to myeloma bone disease…”
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Musculo-skeletal loading conditions at the hip during walking and stair climbing by Heller, M.O, Bergmann, G, Deuretzbacher, G, Dürselen, L, Pohl, M, Claes, L, Haas, N.P, Duda, G.N

“…Musculo-skeletal loading plays an important role in the primary stability of joint replacements and in the biological processes involved in fracture healing…”
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The mechanical heterogeneity of the hard callus influences local tissue strains during bone healing: A finite element study based on sheep experiments by Vetter, A, Liu, Y, Witt, F, Manjubala, I, Sander, O, Epari, D.R, Fratzl, P, Duda, G.N, Weinkamer, R

“…Abstract During secondary fracture healing, various tissue types including new bone are formed. The local mechanical strains play an important role in tissue…”
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Local drug delivery by personalized, intraoperative custom-made implant coating by Trajkovski, B., Petersen, A., Perka, C., Scharnagl, N., Wischke, C., Wagermaier, W., Lendlein, A., Duda, G. N.

“…Local administration of drugs can enhance regeneration, prevent infection, or treat postsurgical pain. If used in conjunction with implants, coating strategies…”
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Do serological tissue turnover markers represent callus formation during fracture healing? by Seebeck, P., Bail, H.J., Exner, C., Schell, H., Michel, R., Amthauer, H., Bragulla, H., Duda, G.N.

“…Serological parameters of bone and fibrous tissue turnover were demonstrated to monitor the course of fracture healing. The aim of this study was to evaluate…”
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European musculoskeletal health and mobility in Horizon 2020: Setting priorities for musculoskeletal research and innovation by Lidgren, L, Gomez-Barrena, E, N Duda, G, Puhl, W, Carr, A

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