Search Results - "Ducray, Stephen P."

The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis by Ducray, Stephen P, Natarajan, Karthikraj, Garland, Gavin D, Turner, Suzanne D, Egger, Gerda

“…Anaplastic lymphoma kinase (ALK) is a tyrosine kinase involved in neuronal and gut development. Initially discovered in T cell lymphoma, ALK is frequently…”
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Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma by Pucci, Perla, Lee, Liam C., Han, Miaojun, Matthews, Jamie D., Jahangiri, Leila, Schlederer, Michaela, Manners, Eleanor, Sorby-Adams, Annabel, Kaggie, Joshua, Trigg, Ricky M., Steel, Christopher, Hare, Lucy, James, Emily R., Prokoph, Nina, Ducray, Stephen P., Merkel, Olaf, Rifatbegovic, Firkret, Luo, Ji, Taschner-Mandl, Sabine, Kenner, Lukas, Burke, G. A. Amos, Turner, Suzanne D.

“…Targeting Anaplastic lymphoma kinase (ALK) is a promising therapeutic strategy for aberrant ALK -expressing malignancies including neuroblastoma, but…”
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Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target by Larose, Hugo, Prokoph, Nina, Matthews, Jamie D, Schlederer, Michaela, Högler, Sandra, Alsulami, Ali F, Ducray, Stephen P, Nuglozeh, Edem, Fazaludeen, Feroze M S, Elmouna, Ahmed, Ceccon, Monica, Mologni, Luca, Gambacorti-Passerini, Carlo, Hoefler, Gerald, Lobello, Cosimo, Pospisilova, Sarka, Janikova, Andrea, Woessmann, Wilhelm, Damm-Welk, Christine, Zimmermann, Martin, Federova, Alina, Malone, Andrea, Smith, Owen, Wasik, Mariusz, Inghirami, Giorgio, Lamant, Laurence, Blundell, Tom L, Klapper, Wolfram, Merkel, Olaf, Burke, Amos G A, Mian, Shahid, Ashankyty, Ibraheem, Kenner, Lukas, Turner, Suzanne D

“…Patients diagnosed with Anaplastic Large Cell Lymphoma (ALCL) are still treated with toxic multi-agent chemotherapy and as many as 25-50% of patients relapse…”
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IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma by Prokoph, Nina, Probst, Nicola A., Lee, Liam C., Monahan, Jack M., Matthews, Jamie D., Liang, Huan-Chang, Bahnsen, Klaas, Montes-Mojarro, Ivonne A., Karaca-Atabay, Elif, Sharma, Geeta G., Malik, Vikas, Larose, Hugo, Forde, Sorcha D., Ducray, Stephen P., Lobello, Cosimo, Wang, Qi, Luan, Shi-Lu, Pospíšilová, Šárka, Gambacorti-Passerini, Carlo, Burke, G. A. Amos, Pervez, Shahid, Attarbaschi, Andishe, Janíková, Andrea, Pacquement, Hélène, Landman-Parker, Judith, Lambilliotte, Anne, Schleiermacher, Gudrun, Klapper, Wolfram, Jauch, Ralf, Woessmann, Wilhelm, Vassal, Gilles, Kenner, Lukas, Merkel, Olaf, Mologni, Luca, Chiarle, Roberto, Brugières, Laurence, Geoerger, Birgit, Barbieri, Isaia, Turner, Suzanne D.

“…Anaplastic large cell lymphoma (ALCL) is a T-cell malignancy predominantly driven by a hyperactive anaplastic lymphoma kinase (ALK) fusion protein. ALK…”
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BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL by Garland, Gavin D, Ducray, Stephen P, Jahangiri, Leila, Pucci, Perla, Amos Burke, G A, Monahan, Jack, Lai, Raymond, Merkel, Olaf, Schiefer, Ana-Iris, Kenner, Lukas, Bannister, Andrew J, Turner, Suzanne D

“…Anaplastic large-cell lymphoma (ALCL) is a T-cell malignancy driven in many cases by the product of a chromosomal translocation, nucleophosmin-anaplastic…”
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The Identification of Novel Epigenetic Therapies for ALK-Driven Haematological Malignancies by Ducray, Stephen P., Trigg, Ricky, Bannister, Andrew J., Lai, Raymond, Egger, Gerda, Merkel, Olaf, Kenner, Lukas, Turner, Suzanne

“…Introduction Through conserved signalling pathways, Anaplastic Lymphoma Kinase (ALK) is well-described in driving haematological malignancies including…”
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