Search Results - "Duchoslav, Eva"

Global Analysis of the Yeast Lipidome by Quantitative Shotgun Mass Spectrometry by Ejsing, Christer S., Sampaio, Julio L., Surendranath, Vineeth, Duchoslav, Eva, Ekroos, Kim, Klemm, Robin W., Simons, Kai, Shevchenko, Andrej

“…Although the transcriptome, proteome, and interactome of several eukaryotic model organisms have been described in detail, lipidomes remain relatively…”
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Differential Mobility Spectrometry-Driven Shotgun Lipidomics by Lintonen, Tuulia P. I, Baker, Paul R. S, Suoniemi, Matti, Ubhi, Baljit K, Koistinen, Kaisa M, Duchoslav, Eva, Campbell, J. Larry, Ekroos, Kim

“…The analysis of lipids by mass spectrometry (MS) can provide in-depth characterization for many forms of biological samples. However, such workflows can also…”
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Characterization of acyl chain position in unsaturated phosphatidylcholines using differential mobility-mass spectrometry[S] by Maccarone, Alan T., Duldig, Jackson, Mitchell, Todd W., Blanksby, Stephen J., Duchoslav, Eva, Campbell, J. Larry

“…Glycerophospholipids (GPs) that differ in the relative position of the two fatty acyl chains on the glycerol backbone (i.e., sn-positional isomers) can have…”
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Automated Identification and Quantification of Glycerophospholipid Molecular Species by Multiple Precursor Ion Scanning by Ejsing, Christer S, Duchoslav, Eva, Sampaio, Julio, Simons, Kai, Bonner, Ron, Thiele, Christoph, Ekroos, Kim, Shevchenko, Andrej

“…We report a method for the identification and quantification of glycerophospholipid molecular species that is based on the simultaneous automated acquisition…”
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Metabolomic spectral libraries for data-independent SWATH liquid chromatography mass spectrometry acquisition by Bruderer, Tobias, Varesio, Emmanuel, Hidasi, Anita O., Duchoslav, Eva, Burton, Lyle, Bonner, Ron, Hopfgartner, Gérard

“…High-quality mass spectral libraries have become crucial in mass spectrometry-based metabolomics. Here, we investigate a workflow to generate accurate mass…”
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A comparison of patient matched meibum and tear lipidomes by Brown, Simon H J, Kunnen, Carolina M E, Duchoslav, Eva, Dolla, Naveen K, Kelso, Michael J, Papas, Eric B, Lazon de la Jara, Percy, Willcox, Mark D P, Blanksby, Stephen J, Mitchell, Todd W

“…To quantify the molecular lipid composition of patient-matched tear and meibum samples and compare tear and meibum lipid molecular profiles. Lipids were…”
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Combining Charge-Switch Derivatization with Ozone-Induced Dissociation for Fatty Acid Analysis by Poad, Berwyck L. J., Marshall, David L., Harazim, Eva, Gupta, Rajesh, Narreddula, Venkateswara R., Young, Reuben S. E., Duchoslav, Eva, Campbell, J. Larry, Broadbent, James A., Cvačka, Josef, Mitchell, Todd W., Blanksby, Stephen J.

“…The specific positions of carbon–carbon double bond(s) within an unsaturated fatty acid exert a significant effect on the physical and chemical properties of…”
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Shotgun Lipidomics by Sequential Precursor Ion Fragmentation on a Hybrid Quadrupole Time-of-Flight Mass Spectrometer by Simons, Brigitte, Kauhanen, Dimple, Sylvänne, Tuulia, Tarasov, Kirill, Duchoslav, Eva, Ekroos, Kim

“…Shotgun lipidomics has evolved into a myriad of multi-dimensional strategies for molecular lipid characterization, including bioinformatics tools for mass…”
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Software-aided detection and structural characterization of cyclic peptide metabolites in biological matrix by high-resolution mass spectrometry by Yao, Ming, Cai, Tingting, Duchoslav, Eva, Ma, Li, Guo, Xu, Zhu, Mingshe

“…Compared to their linear counterparts, cyclic peptides show better biological activities, such as antibacterial, immunosuppressive, and anti-tumor activities,…”
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Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: A tool for monitoring PE metabolism by Bilgin, Mesut, Markgraf, Daniel F., Duchoslav, Eva, Knudsen, Jens, Jensen, Ole N., de Kroon, Anton I.P.M., Ejsing, Christer S.

“…We report a method for the simultaneous identification and quantification of phosphatidylethanolamine (PE), monomethyl-phosphatidylethanolamine (MMPE),…”
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Fast Electron Detachment Dissociation of Oligonucleotides in Electron-Nitrogen Plasma Stored in Magneto Radio-Frequency Ion Traps by Karasawa, Kaoru, Duchoslav, Eva, Baba, Takashi

“…We report “plasma” electron detachment dissociation (EDD), a novel electron-activated dissociation (EAD) method for the fast sequencing of oligonucleotides…”
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A High-Capacity LC/MS System for the Bioanalysis of Samples Generated from Plate-Based Metabolic Screening by Janiszewski, John S, Rogers, Katrina J, Whalen, Kevin M, Cole, Mark J, Liston, Theodore E, Duchoslav, Eva, Fouda, Hassan G

“…HPLC/MS is a linear technique characterized by serial injection and analysis of individual samples. Parallel-format high-throughput screens for druglike…”
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Qualitative analysis and quantitative assessment of changes in neutral glycerol lipid molecular species within cells by Krank, Jessica, Murphy, Robert C, Barkley, Robert M, Duchoslav, Eva, McAnoy, Andrew

“…Triacylglycerols (TAGs) and diacylglycerols (DAGs) are present in cells as a complex mixture of molecular species that differ in the nature of the fatty acyl…”
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Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry by Karasawa, Kaoru, Duchoslav, Eva, Burton, Lyle, Kawakami, Junji, Baba, Takashi

“…We report the first sequencing of morpholino antisense oligonucleotides (phosphorodiamidate morpholino oligomers, PMOs) using electron capture dissociation…”
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Dissociation of Biomolecules by an Intense Low-Energy Electron Beam in a High Sensitivity Time-of-Flight Mass Spectrometer by Baba, Takashi, Ryumin, Pavel, Duchoslav, Eva, Chen, Keqin, Chelur, Anjali, Loyd, Bill, Chernushevich, Igor

“…We report the progress on an electron-activated dissociation (EAD) device coupled to a quadrupole TOF mass spectrometer (QqTOF MS) developed in our group. This…”
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Development of an automated mass spectrometry system for the quantitative analysis of liver microsomal incubation samples: a tool for rapid screening of new compounds for metabolic stability by Korfmacher, Walter A., Palmer, Cynthia A., Nardo, Cymbelene, Dunn-Meynell, Kimberly, Grotz, Diane, Cox, Kathleen, Lin, Chin-Chung, Elicone, Chris, Liu, Charles, Duchoslav, Eva

“…There is a continuing need for increased throughput in the evaluation of new drug entities in terms of their pharmacokinetic parameters. One useful parameter…”
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Hybrid SWATH/MS and HR-SRM/MS acquisition for phospholipidomics using QUAL/QUANT data processing by Raetz, Michel, Duchoslav, Eva, Bonner, Ron, Hopfgartner, Gérard

“…A hybrid SWATH/MS and HR-SRM/MS acquisition approach using multiple unit mass windows and 100 u precursor selection windows has been developed to interface…”
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Discrimination of isobaric and isomeric lipids in complex mixtures by combining ultra-high pressure liquid chromatography with collision and ozone-induced dissociation by Batarseh, Amani M., Abbott, Sarah K., Duchoslav, Eva, Alqarni, Ayedh, Blanksby, Stephen J., Mitchell, Todd W.

“…[Display omitted] •A unique mass spectrometry workflow for enhanced lipid isomer identification.•New software for automated annotation of ozone-induced…”
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Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry by Murphy, Robert C., James, Patrick F., McAnoy, Andrew M., Krank, Jessica, Duchoslav, Eva, Barkley, Robert M.

“…Triacylglycerols (TAGs) are neutral lipids present in all mammalian cells as energy reserves, and diacylglycerols (DAGs) are present as intermediates in…”
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Rapid screening and characterization of drug metabolites using multiple ion monitoring dependent product ion scan and postacquisition data mining on a hybrid triple quadrupole-linear ion trap mass spectrometer by Yao, Ming, Ma, Li, Duchoslav, Eva, Zhu, Mingshe

“…Multiple ion monitoring (MIM)‐dependent acquisition with a triple quadrupole‐linear ion trap mass spectrometer (Q‐trap) was previously developed for drug…”
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