Search Results - "Duchonova, B"

Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma by Obazee, O., Archibugi, L., Andriulli, A., Soucek, P., Małecka‐Panas, E., Ivanauskas, A., Johnson, T., Gazouli, M., Pausch, T., Lawlor, R. T., Cavestro, G. M., Milanetto, A. C., Di Leo, M., Pasquali, C., Hegyi, P., Szentesi, A., Radu, C. E., Gheorghe, C., Theodoropoulos, G. E., Bergmann, F., Brenner, H., Vodickova, L., Katzke, V., Campa, D., Strobel, O., Kaiser, J., Pezzilli, R., Federici, F., Mohelnikova‐Duchonova, B., Boggi, U., Lemstrova, R., Johansen, J. S., Bojesen, S. E., Chen, I., Jensen, B. V., Capurso, G., Pazienza, V., Dervenis, C., Sperti, C., Mambrini, A., Hackert, T., Kaaks, R., Basso, D., Talar‐Wojnarowska, R., Maiello, E., Izbicki, J. R., Cuk, K., Saum, K. U., Cantore, M., Kupcinskas, J., Palmieri, O., Delle Fave, G., Landi, S., Salvia, R., Fogar, P., Vashist, Y. K., Scarpa, A., Vodicka, P., Tjaden, C., Iskierka‐Jazdzewska, E., Canzian, F.

“…Rare truncating BRCA2 K3326X (rs11571833) and pathogenic CHEK2 I157T (rs17879961) variants have previously been implicated in familial pancreatic ductal…”
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The role of ABC transporters in progression and clinical outcome of colorectal cancer by Hlavata, I., Mohelnikova-Duchonova, B., Vaclavikova, R., Liska, V., Pitule, P., Novak, P., Bruha, J., Vycital, O., Holubec, L., Treska, V., Vodicka, P., Soucek, P.

“…Worldwide, colorectal cancer (CRC) is the third most common cancer, with the highest mortality rates occurring in Central Europe. The use of chemotherapy to…”
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Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216 by Mohelnikova-Duchonova, B, Kocik, M, Duchonova, B, Brynychova, V, Oliverius, M, Hlavsa, J, Honsova, E, Mazanec, J, Kala, Z, Ojima, I, Hughes, D J, Doherty, J E, Murray, H A, Crockard, M A, Lemstrova, R, Soucek, P

“…The Hedgehog pathway is one of the major driver pathways in pancreatic ductal adenocarcinoma. This study investigated prognostic importance of Hedgehog…”
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Next-generation sequencing of pancreatic cancer revealed differentially mutated genes between primary tumors and lung metastases by Hlavac, Viktor, Mohelnikova-Duchonova, B., Lovecek, M., Ehrmann, J., Brynychova, V., Kolarova, K., Soucek, P.

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DNA-repair pathway expression changes and their correlation with PDAC sensitivity to PARP- inhibitor and chemotherapy combination by Mohelnikova-Duchonova, B., Strouhal, O., Zemanek, T., Kolarova, K., Flasarova, D., Dvorak, P., Soucek, P.

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Bacterobilia in patients with pancreatic ductal adenocarcinoma undergoing pancreatoduodenectomy – microbial profile analysis and clinical impact by Skalicky, P., Lovecek, M., Klos, D., Jerabkova, J., Knapkova, K., Loveckova, Y., Kolar, M., Mohelníkova Duchonova, B.

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KRAS pathway expression changes in pancreatic cancer models by conventional and experimental taxanes by Oliverius, M, Flasarova, D, Mohelnikova-Duchonova, B, Ehrlichova, M, Hlavac, V, Kocik, M, Strouhal, O, Dvorak, P, Ojima, I, Soucek, P

“…The KRAS signalling pathway is pivotal for pancreatic ductal adenocarcinoma (PDAC) development. After the failure of most conventional cytotoxic and targeted…”
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Polymorphisms in Transcription Factor Binding Sites and Enhancers as Pancreatic Ductal Adenocarcinoma Risk Factors by Unal, Pelin, Lu, Y., Aoki, M., Chammas, R., Gazouli, M., Theodoropoulos, G., van Eijck, C., Bijlsma, M., Dijk, F., Bueno-de-Mesquita, B., Kupcinskas, J., Kiudelis, V., Kreivenaite, E., Kondrackiene, J., Malecka-Wojciesko, E., Talar-Wojnarowska, R., Kapszewicz, M., Hegyi, P., Szentesi, A., Eross, B., Bunduc, S., Mohelnikova-Duchonova, B., Soucek, P., Hlavac, V., Oliverius, M., Vodickova, L., Cervena, K., Hackert, T., Neoptolemos, J., Goetz, M., Uzunoglu, F., Izbicki, J., Stocker, H., Schöttker, B., Brenner, H., Perri, F., Tavano, F., Palmieri, O., Bazzocchi, F., Maiello, E., Testoni, S., Petrone, M., Arcidiacono, P., Landi, S., Ermini, S., Bambi, F., Boggi, U., Capurso, G., Archibugi, L., Vanella, G., Cavestro, G., Morelli, L., Di Franco, G., Milanetto, A., Sperti, C., Pasquali, C., Basso, D., Pezzilli, R., Lawlor, R., Capretti, G., Carrara, S., Campa, D., Canzian, F.

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Lack of association of CD44-rs353630 and CHI3L2-rs684559 with pancreatic ductal adenocarcinoma survival by Corradi, C., Gentiluomo, M., Vanella, G., Johansen, A.Z., Loos, M., Szentesi, A., Milanetto, A.C., Hegyi, P., Kupcinskas, J., Tavano, F., Schneider, M., Bozzato, D., Neoptolemos, J.P., Hackert, T., Pezzilli, R., Johansen, J.S., Costello, E., Mohelnikova-Duchonova, B., van Eijck, C.H.J., Talar-Wojnarowska, R., Hansen, C. Palnæs, Darvasi, E., Chen, I.M., Cavestro, G.M., Soucek, P., Piredda, L., Vodicka, P., Gazouli, M., Arcidiacono, P.G., Canzian, F., Campa, D., Capurso, G.

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Association of variants of genes involved in mitochondrial metabolism with pancreatic cancer risk by Peduzzi, G., Gentiluomo, M., Tavano, F., Arcidiacono, P.G., Ermini, S., Boggi, U., Cavestro, G.M., Capurso, G., Morelli, L., Milanetto, A.C., Pezzilli, R., Lawlor, R.T., Carrara, S., Lovecek, M., Souček, P., . Vodičková, Guo, F., Hackert, T., Uzunoğlu, F.G., Gazouli, M., Párniczky, A., Kupcinskas, J., Bijlsm, M.F., Bueno-de-Mesquita, B., Vermeulen, R.C.H., van Eijck, C.H.J., Jamroziak, K., Talar-Wojnarowska, R., Greenhalf, W., Gioffreda, D., Petrone, M.C., Landi, S., Archibugi, L., Puzzono, M., Funel, N., Sperti, C., Piredda, M.L., Mohelnikova-Duchonova, B., Hlaváč, V., Gao, X., Schneider, M., Izbicki, J.R., Theodoropoulos, G., Bunduc, S., Kreivenaite, E., Busch, O.R., Małecka-Panas, E., Costello, E., Perri, F., Testoni, S.G.G., Vanella, G., Pasquali, C., Oliverius, M., H.Brenner, Loos, M., Götz, M., Georgiou, K., Erőss, B., Maiello, E., Szentes i, A., Bazzocchi, F., Basso, D., Neoptolemos, J.P., Hegyi, P., Kiudelis, V., Canzian, F., Campa, D.

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Polymorphic variants within non-coding RNA and risk of pancreatic ductal adenocarcinoma by Gentiluomo, M., Corradi, C., Lu, Y., Giaccherini, M., Hegyi, P., Pezzilli, R., Tavano, F., Szentesi, A., Gajdán, L., Nentwich, M., Strobel, O., Gazouli, M., Cavestro, G., Darvasi, E., Arcidiacono, P., Landi, S., Luchini, C., Gioffreda, D., Kupcinskas, J., Hackert, T., Neoptolemos, J., Morelli, L., Kreivenaite, E., Zuppardo, R., Carrara, S., Di Franco, G., Brenner, H., Hlavac, V., Sperti, C., Milanetto, A., Moz, S., Mohelnikova-Duchonova, B., Petrone, M., Lawlor, R., Vanella, G., Vashist, Y., Soucek, P., Vodicka, P., Cervena, K., Capurso, G., Malecka-Panas, E., Pasquali, C., Archibugi, Gheorghe, C., Andriulli, A., Ivanauskas, A., Theodoropoulos, G., Jamroziak, K., Izbicki, J., Testoni, S., Oliverius, M., Napoli, N., Canzian, F., Campa, D.

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Associations between pancreatic expression quantitative trait loci (eQTLs) and pancreatic ductal adenocarcinoma risk by Gentiluomo, M., Pistoni, L., Peduzzi, G., Lu, Y., Macauda, A., Hlavac, V., Vanella, G., Darvasi, E., Milanetto, A., Oliverius, M., Vashist, Y., Di Leo, M., Mohelnikova-Duchonova, B., Talar-Wojnarowska, R., Gheorghe, C., Petrone, M., Strobel, O., Arcidiacono, P., Vodickova, L., Szentesi, A., Capurso, G., Gajdán, L., Malleo, G., Theodoropoulos, G., Basso, D., Soucek, P., Brenner, H., Lawlor, R., Morelli, L., Ivanauskas, A., Kauffmann, E., Gázouli, M., Archibugi, Nentwich, M., Lovecek, M., Cavestro, G., Vodicka, P., Landi, S., Tavano, F., Sperti, C., Hackert, T., Kupcinskas, J., Pezzilli, R., Andriulli, A., Pollina, L., Kreivenaite, E., Gioffreda, D., Jamroziak, K., Hegyi, P., Izbicki, J., Testoni, S., Zuppardo, R., Bozzato, D., Neoptolemos, J., Canzian, F., Campa, D.

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The association between glutathione S-transferase gene polymorphisms and pancreatic cancer in a central European Slavonic population by Vrana, D., Pikhart, H., Mohelnikova-Duchonova, B., Holcatova, I., Strnad, R., Slamova, A., Schejbalova, M., Ryska, M., Susova, S., Soucek, P.

“…In the first case-control study on pancreatic cancer conducted on 253 cases and 403 controls in the Czech Republic we observed that the GSTP1-codon 105 Val…”
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Polymorphisms in metabolizing enzymes and the risk of head and neck squamous cell carcinoma in the Slavic population of the central Europe by Soucek, P, Susova, S, Mohelnikova-Duchonova, B, Gromadzinska, J, Moraviec-Sztandera, A, Vodicka, P, Vodickova, L

“…The question of susceptibility to squamous cell carcinoma of head and neck (SCCHN) in the environmental context was addressed by analysis of functional…”
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6021 POSTER The Role of ABC Transporter Genes in Colorectal Cancer Resistance by Hlavata, I, Mohelnikova-Duchonova, B, Vaclavikova, R, Liska, V, Novak, P, Holubec, L, Pitule, P, Vycital, O, Bruha, J, Soucek, P

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Differences In Gene Expression Of ABC Transporters In Pancreatic Adenocarcinoma by Mohelnikova-Duchonova, B, Brynychova, V, Oliverius, M, Kala, Z, Honsova, E, Muckova, K, Penka, I, Prochazka, V, Hlavsa, J, Souček, P

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PJY18 Post-chemotherapy robot-assisted retroperitoneal lymph node dissection for testicular cancer: A single center experience by Študent, V.R.J., Hartmann, I., Mohelnikova-Duchonova, B., Studentova, H.

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Polymorphic variants involved in methylation regulation: a new strategy to discover risk loci for pancreatic ductal adenocarcinoma by Corradi, Chiara, Lencioni, G., Gentiluomo, M., Latiano, A., Kiudelis, G., van Eijck, C., Marta, K., Lawlor, R., Tavano, F., Boggi, U., Dijk, F., Cavestro, G., Vermeulen, R., Hackert, T., Petrone, M., Uzunoglu, F., Archibugi, L., Izbicki, J., Mesquita, B. Bueno-de, Morelli, L., Zerbi, A., Stocker, H., Talar-Wojnarowska, R., Di Franco, G., Hegyi, P., Sperti, C., Carrara, S., Capurso, G., Gazouli, M., Brenner, H., Bunduc, S., Busch, O., Landi, S., Perri, F., Oliverius, M., Goetz, M., Scognamiglio, P., Mambrini, A., Arcidiacono, P., Kreivenaite, E., Kupcinskas, J., Hussein, T., Ermini, S., Milanetto, A., Vodicka, P., Kiudelis, V., Hlavac, V., Soucek, P., Theodoropoulos, G., Basso, D., Aoki, M., Pezzilli, R., Pasquali, C., Chammas, R., Testoni, S., Mohelníková-Duchoňová, B., Lucchesi, M., Neoptolemos, J., Canzian, F., Campa, D.

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Identification of recessively inherited genetic variants for pancreatic cancer risk by Lu, Y., Gentiluomo, M., Macauda, A., Gioffreda, D., Gazouli, M., Petrone, M.C., Kelemen, D., L.Ginocchi, Morelli, L., Papiris, K., Greenhalf, W., Izbicki, J.R., Kiudelis, V., Mohelníková-Duchoňová, B., Bueno-de-Mesquita, B., Vodicka, P., Brenner, H., Diener, M.K., Pezzilli, R., Ivanauskas, A., Salvia, R., Szentesi, A., Aoki, M.N., Németh, B.C., Sperti, C., Jamroziak, K., Chammas, R., Oliverius, M., Archibugi, L., Ermini, S., Novák, J., Kupcinskas, J., Strouhal, O., Souček, P., Cavestro, G.M., Milanetto, A.C., Vanella, G., Neoptolemos, J.P., Theodoropoulos, G.E., van Laarhoven, H.W.M., Mambrini, A., Moz, S., Kala, Z., Loveček, M., Basso, D., Uzunoglu, F.G., Hackert, T., Testoni, S.G.G., Hlavac, V., Andriulli, A., Lucchesi, M., Tavano, F., Carrara, S., Hegyi, P., Arcidiacono, P.G., Busch, O.R., Lawlor, R.T., Puzzono, M., Boggi, U., Guo, F., Małecka-Panas, E., Capurso, G., Landi, S., R.Talar-Wojnarowska, Strobel, O., Gao, X., Vashist, Y., Campa, D., Canzian, F.

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FOLFOX/FOLFIRI pharmacogenetics:The call for a personalized approach in colorectal cancer therapy by Beatrice Mohelnikova-Duchonova Bohuslav Melichar Pavel Soucek

“…While 5-fluorouracil used as single agent in patients with metastatic colorectal cancer has an objective response rate around 20%,the administration of…”
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