Search Results - "Duchen, L W"

The mutant mdx: inherited myopathy in the mouse. Morphological studies of nerves, muscles and end-plates by Torres, L F, Duchen, L W

“…The mdx mutant mouse was first observed during a survey of genetic variations of pyruvate kinase in the mouse. Affected mice have high serum levels of this…”
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Dementia associated with a 216 base pair insertion in the prion protein gene. Clinical and neuropathological features by Duchen, L W, Poulter, M, Harding, A E

“…We report the clinical and neuropathological findings in a patient with a 216 base pair insertion in the prion protein (PrP) gene. She died aged 57 years after…”
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Cerebral amyloid in human prion disease by Watanabe, R, Duchen, L W

“…The clinical and neuropathological features of 21 patients with prion disease were reviewed with special reference to the morphology and immunoreactivity of…”
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Evidence for the experimental transmission of cerebral β-amyloidosis to primates by BAKER, H. F, RIDLEY, R. M, DUCHEN, L. W, CROW, T. J, BRUTON, C. J

“…The brains of three marmosets (Callithrix jacchus) injected intracerebrally 6-7 years earlier with brain tissue from a patient with early onset Alzheimer's…”
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Induction of beta (A4)-amyloid in primates by injection of Alzheimer's disease brain homogenate. Comparison with transmission of spongiform encephalopathy by Baker, H F, Ridley, R M, Duchen, L W, Crow, T J, Bruton, C J

“…Amyloid plaques, associated with argyrophilic dystrophic neurites, and cerebral amyloid angiopathy (CAA), but no neurofibrillary tangles, were found in the…”
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Creutzfeldt-Jakob disease and lyophilised dura mater grafts: report of two cases by Esmonde, T, Lueck, C J, Symon, L, Duchen, L W, Will, R G

“…Two further cases of Creutzfeldt-Jakob disease (CJD) in association with cadaveric dura mater grafts are described. The clinical features of all such reported…”
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Distal motor axonopathy and central nervous system myelin vacuolation caused by cycloleucine, an inhibitor of methionine adenosyltransferase by Lee, C C, Surtees, R, Duchen, L W

“…Cycloleucine (CL), an inhibitor of methionine adenosyltransferase, has previously been used to produce an experimental model of subacute combined degeneration…”
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Mitochondrial DNA mutation underlying Leigh's syndrome: clinical, pathological, biochemical, and genetic studies of a patient presenting with progressive myoclonic epilepsy by Sweeney, M G, Hammans, S R, Duchen, L W, Cooper, J M, Schapira, A H, Kennedy, C R, Jacobs, J M, Youl, B D, Morgan-Hughes, J A, Harding, A E

“…An 18-year-old male patient presented with clinical and radiological evidence of Leigh's syndrome (LS), having developed progressive myoclonic epilepsy and…”
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Current status review : cerebral amyloid by DUCHEN, L. W

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Pathology of autonomic neuropathy in diabetes mellitus by Duchen, L W, Anjorin, A, Watkins, P J, Mackay, J D

“…Pathologic changes in the autonomic nervous system were studied postmortem in five cases of insulin-dependent diabetes of early onset. All had had clinical…”
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A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndrome by Kennedy, P G, Duchen, L W

“…The intermediolateral column neurons in the lateral horns of the grey matter of the thoracic spinal cord were counted in five patients who had died of motor…”
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Brown-Vialetto-Van Laere syndrome by Francis, D A, Ponsford, J R, Wiles, C M, Thomas, P K, Duchen, L W

“…The clinical and pathological findings of a male with the Brown-Vialetto-Van Laere syndrome are described. This rare and fatal affection of the nervous system…”
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The evolution of an experimental distal motor axonopathy. Physiological studies of changes in neuromuscular transmission caused by cycloleucine, an inhibitor of methionine adenosyltransferase by Edwards, J P, Lee, C C, Duchen, L W

“…Cycloleucine (CL), a synthetic amino acid is known to cause degeneration of motor nerve terminals. This paper describes the changes in neuromuscular…”
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Kluver-Bucy syndrome in Pick disease: clinical and pathologic correlations by Cummings, J L, Duchen, L W

“…The clinical and neuropathologic findings of five cases of Pick disease were studied. All had severe anterior temporal atrophy and abnormal neurons with highly…”
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Spongiform encephalopathy transmitted experimentally from Creutzfeldt-Jakob and familial Gerstmann-Sträussler-Scheinker diseases by Baker, H F, Duchen, L W, Jacobs, J M, Ridley, R M

“…A comparison was made of the effects of experimental intracerebral inoculation into marmosets of brain homogenates from a case of Creutzfeldt-Jakob disease…”
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Experimental induction of beta-amyloid plaques and cerebral angiopathy in primates by Baker, H F, Ridley, R M, Duchen, L W, Crow, T J, Bruton, C J

“…Moderate numbers of amyloid plaques with associated argyrophilic dystrophic neurites and cerebral amyloid angiopathy (CAA) but no neurofibrillary tangles…”
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End-plates, transmission and contractile characteristics of muscles without spindles in the hereditary sensory neuropathy of the Sprawling mouse by Brook, G A, Duchen, L W

“…In the mutant mouse Sprawling, a deficiency of sensory ganglion cells is associated with a failure of the development of spindles and tendon organs…”
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Hereditary leucodystrophy in the mouse: the new mutant twitcher by Duchen, L W, Eicher, E M, Jacobs, J M, Scaravilli, F, Teixeira, F

“…A new inherited neurological disease in the mouse (the mutant twitcher) has been studied. Transmission is by an autosomal recessive gene (twi). Affected…”
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Changes in motor innervation and cholinesterase localization induced by botulinum toxin in skeletal muscle of the mouse: differences between fast and slow muscles by Duchen, L W

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Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) with amyloid angiopathy by Keohane, C, Peatfield, R, Duchen, L W

“…A case is reported of Creutzfeldt-Jakob disease associated with amyloid infiltration of cerebral vessels. The duration of progressive dementia was only 4…”
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