Search Results - "Ducharme, Simon"

Apathy: a neurocircuitry model based on frontotemporal dementia by Ducharme, Simon, Price, Bruce H, Dickerson, Bradford C

“…Apathy is a symptom shared among many neurological and psychiatric disorders. However, the underlying neurocircuitry remains incompletely understood. Apathy is…”
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Psychiatric Presentations of C9orf72 Mutation: What Are the Diagnostic Implications for Clinicians? by Ducharme, Simon, Bajestan, Sepideh, Dickerson, Bradford C, Voon, Valerie

“…The C9orf72 mutation was identified as the most frequent genetic cause of frontotemporal dementia (FTD). In light of multiple reports of predominant…”
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Trajectories of cortical thickness maturation in normal brain development — The importance of quality control procedures by Ducharme, Simon, Albaugh, Matthew D., Nguyen, Tuong-Vi, Hudziak, James J., Mateos-Pérez, J.M., Labbe, Aurelie, Evans, Alan C., Karama, Sherif

“…Several reports have described cortical thickness (CTh) developmental trajectories, with conflicting results. Some studies have reported inverted-U shape…”
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18F-MK-6240 tau-PET in genetic frontotemporal dementia by Levy, Jake P, Bezgin, Gleb, Savard, Melissa, Pascoal, Tharick A, Finger, Elizabeth, Laforce, Robert, Sonnen, Joshua A, Soucy, Jean-Paul, Gauthier, Serge, Rosa-Neto, Pedro, Ducharme, Simon

“…Tau is one of several proteins associated with frontotemporal dementia. While knowing which protein is causing a patient's disease is crucial, no biomarker…”
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Clinical Approach to the Differential Diagnosis Between Behavioral Variant Frontotemporal Dementia and Primary Psychiatric Disorders by Ducharme, Simon, Price, Bruce H., Larvie, Mykol, Dougherty, Darin D., Dickerson, Bradford C.

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The Neuropsychiatric Examination of the Young-Onset Dementias by Ducharme, Simon, MD, MSc, Dickerson, Bradford C., MD

“…Young-onset dementias frequently present with prominent behavioral features and constitute a diagnostic challenge. Most cases are secondary to…”
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Deformation based morphometry study of longitudinal MRI changes in behavioral variant frontotemporal dementia by Manera, Ana L., Dadar, Mahsa, Collins, D. Louis, Ducharme, Simon

“…•The expected atrophy was shown in the frontal lobes and anterior temporal regions.•Subcortical structures were notably affected in our bvFTD…”
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Eye movement function captured via an electronic tablet informs on cognition and disease severity in Parkinson’s disease by Koch, Nils A., Voss, Patrice, Cisneros-Franco, J. Miguel, Drouin-Picaro, Alexandre, Tounkara, Fama, Ducharme, Simon, Guitton, Daniel, de Villers-Sidani, Étienne

“…Studying the oculomotor system provides a unique window to assess brain health and function in various clinical populations. Although the use of detailed…”
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Maturational trajectories of pericortical contrast in typical brain development by Drakulich, Stefan, Thiffault, Anne-Charlotte, Olafson, Emily, Parent, Olivier, Labbe, Aurelie, Albaugh, Matthew D., Khundrakpam, Budhachandra, Ducharme, Simon, Evans, Alan, Chakravarty, Mallar M., Karama, Sherif

“…•Gray-white contrast (GWC) decreases in most areas of the cortex in early life.•The trajectories of GWC decline tend to be cubic across the…”
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Ventricular features as reliable differentiators between bvFTD and other dementias by Manera, Ana L., Dadar, Mahsa, Collins, D. Louis, Ducharme, Simon

“…•Our results showed a consistent pattern of ventricle enlargement in the bvFTD patients, particularly in the anterior parts of the frontal and temporal horns…”
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Morphometric MRI as a diagnostic biomarker of frontotemporal dementia: A systematic review to determine clinical applicability by McCarthy, Jillian, Collins, D. Louis, Ducharme, Simon

“…Frontotemporal dementia (FTD) is difficult to diagnose, due to its heterogeneous nature and overlap in symptoms with primary psychiatric disorders. Brain MRI…”
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Cortical Thickness Maturation and Duration of Music Training: Health-Promoting Activities Shape Brain Development by Hudziak, James J., MD, Albaugh, Matthew D., PhD, Ducharme, Simon, MD, Karama, Sherif, MD, PhD, Spottswood, Margaret, MD, Crehan, Eileen, BA, Evans, Alan C., PhD, Botteron, Kelly N., MD

“…Objective To assess the extent to which playing a musical instrument is associated with cortical thickness development among healthy youths. Method…”
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Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes by Malpetti, Maura, Jones, P. Simon, Tsvetanov, Kamen A., Rittman, Timothy, Swieten, John C., Borroni, Barbara, Sanchez‐Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Frisoni, Giovanni B., Ghidoni, Roberta, Sorbi, Sandro, Heller, Carolin, Todd, Emily G., Bocchetta, Martina, Cash, David M., Convery, Rhian S., Peakman, Georgia, Moore, Katrina M., Rohrer, Jonathan D., Kievit, Rogier A., Rowe, James B., GENFI - Genetic Frontotemporal dementia Initiative

“…© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association. This is an open access article under the…”
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Factors Associated With Burnout, Post-traumatic Stress and Anxio-Depressive Symptoms in Healthcare Workers 3 Months Into the COVID-19 Pandemic: An Observational Study by Cyr, Samuel, Marcil, Marie-Joelle, Marin, Marie-France, Tardif, Jean-Claude, Guay, Stéphane, Guertin, Marie-Claude, Rosa, Camille, Genest, Christine, Forest, Jacques, Lavoie, Patrick, Labrosse, Mélanie, Vadeboncoeur, Alain, Selcer, Shaun, Ducharme, Simon, Brouillette, Judith

“…Objective: This study examined how best to identify modifiable protective and risk factors for burnout in healthcare workers in the face of the COVID-19…”
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Decreased Regional Cortical Thickness and Thinning Rate Are Associated With Inattention Symptoms in Healthy Children by Ducharme, Simon, M.D., M.Sc, Hudziak, James J., M.D, Botteron, Kelly N., M.D, Albaugh, Matthew D., B.A, Nguyen, Tuong-Vi, M.D., M.Sc, Karama, Sherif, M.D, Evans, Alan C., Ph.D

“…Objective Children with attention-deficit/hyperactivity disorder (ADHD) have delayed cortical maturation, evidenced by regionally specific slower cortical…”
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Evolution of burnout and psychological distress in healthcare workers during the COVID-19 pandemic: a 1-year observational study by Cyr, Samuel, Marcil, Marie-Joelle, Houchi, Cylia, Marin, Marie-France, Rosa, Camille, Tardif, Jean-Claude, Guay, Stéphane, Guertin, Marie-Claude, Genest, Christine, Forest, Jacques, Lavoie, Patrick, Labrosse, Mélanie, Vadeboncoeur, Alain, Selcer, Shaun, Ducharme, Simon, Brouillette, Judith

“…Long-term psychological impacts of the COVID-19 pandemic on healthcare workers remain unknown. We aimed to determine the one-year progression of burnout and…”
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MRI and cognitive scores complement each other to accurately predict Alzheimer's dementia 2 to 7 years before clinical onset by Zandifar, Azar, Fonov, Vladimir S., Ducharme, Simon, Belleville, Sylvie, Collins, D. Louis

“…•The study is run on 756 aMCI subjects from the ADNI multi-center cohort study.•Cognitive scores and MRI features achieves 87% prediction accuracy at 5…”
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A novel tablet-based software for the acquisition and analysis of gaze and eye movement parameters: a preliminary validation study in Parkinson's disease by de Villers-Sidani, Étienne, Voss, Patrice, Guitton, Daniel, Cisneros-Franco, J Miguel, Koch, Nils A, Ducharme, Simon

“…The idea that eye movements can reflect certain aspects of brain function and inform on the presence of neurodegeneration is not a new one. Indeed, a growing…”
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Bifrontal Hypermetabolism on Brain FDG-PET in a Case of C9orf72-Related Behavioral Variant of Frontotemporal Dementia by Levy, Jake P, Bocti, Christian, Elie, Dominique, Paquet, Nancy, Soucy, Jean-Paul, Ducharme, Simon

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Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche by Jones, Sherri Lee, De Braga, Victoria, Caccese, Christina, Lew, Jimin, Elgbeili, Guillaume, Castellanos-Ryan, Natalie, Parent, Sophie, Muckle, Gina, Herba, Catherine M, Fraser, William D, Ducharme, Simon, Barnwell, Julia, Trasler, Jacquetta, Séguin, Jean R, Nguyen, Tuong-Vi, Montreuil, Tina C

“…This study examined (1) whether measures of paternal anxious and depressive symptoms collected prenatally and during a follow-up assessment when the child was…”
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