Search Results - "Ducat, Sarah"

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques by Aid, Malika, Busman-Sahay, Kathleen, Vidal, Samuel J., Maliga, Zoltan, Bondoc, Stephen, Starke, Carly, Terry, Margaret, Jacobson, Connor A., Wrijil, Linda, Ducat, Sarah, Brook, Olga R., Miller, Andrew D., Porto, Maciel, Pellegrini, Kathryn L., Pino, Maria, Hoang, Timothy N., Chandrashekar, Abishek, Patel, Shivani, Stephenson, Kathryn, Bosinger, Steven E., Andersen, Hanne, Lewis, Mark G., Hecht, Jonathan L., Sorger, Peter K., Martinot, Amanda J., Estes, Jacob D., Barouch, Dan H.

“…The COVID-19 pandemic has led to extensive morbidity and mortality throughout the world. Clinical features that drive SARS-CoV-2 pathogenesis in humans include…”
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Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters by McMahan, Katherine, Giffin, Victoria, Tostanoski, Lisa H, Chung, Benjamin, Siamatu, Mazuba, Suthar, Mehul S, Halfmann, Peter, Kawaoka, Yoshihiro, Piedra-Mora, Cesar, Jain, Neharika, Ducat, Sarah, Kar, Swagata, Andersen, Hanne, Lewis, Mark G, Martinot, Amanda J, Barouch, Dan H

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant has proven to be highly transmissible and has outcompeted the…”
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Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques by Aid, Malika, Vidal, Samuel J, Piedra-Mora, Cesar, Ducat, Sarah, Chan, Chi N, Bondoc, Stephen, Colarusso, Alessandro, Starke, Carly E, Nekorchuk, Michael, Busman-Sahay, Kathleen, Estes, Jacob D, Martinot, Amanda J, Barouch, Dan H

“…Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 WA1/2020 challenge and are therefore useful models of COVID-19 pathogenesis and…”
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SARS-CoV-2 infection protects against rechallenge in rhesus macaques by Chandrashekar, Abishek, Liu, Jinyan, Martinot, Amanda J, McMahan, Katherine, Mercado, Noe B, Peter, Lauren, Tostanoski, Lisa H, Yu, Jingyou, Maliga, Zoltan, Nekorchuk, Michael, Busman-Sahay, Kathleen, Terry, Margaret, Wrijil, Linda M, Ducat, Sarah, Martinez, David R, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S, Slein, Matthew D, Pessaint, Laurent, Van Ry, Alex, Greenhouse, Jack, Taylor, Tammy, Blade, Kelvin, Cook, Anthony, Finneyfrock, Brad, Brown, Renita, Teow, Elyse, Velasco, Jason, Zahn, Roland, Wegmann, Frank, Abbink, Peter, Bondzie, Esther A, Dagotto, Gabriel, Gebre, Makda S, He, Xuan, Jacob-Dolan, Catherine, Kordana, Nicole, Li, Zhenfeng, Lifton, Michelle A, Mahrokhian, Shant H, Maxfield, Lori F, Nityanandam, Ramya, Nkolola, Joseph P, Schmidt, Aaron G, Miller, Andrew D, Baric, Ralph S, Alter, Galit, Sorger, Peter K, Estes, Jacob D, Andersen, Hanne, Lewis, Mark G, Barouch, Dan H

“…An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies…”
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Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters by Tostanoski, Lisa H., Wegmann, Frank, Martinot, Amanda J., Loos, Carolin, McMahan, Katherine, Mercado, Noe B., Yu, Jingyou, Chan, Chi N., Bondoc, Stephen, Starke, Carly E., Nekorchuk, Michael, Busman-Sahay, Kathleen, Piedra-Mora, Cesar, Wrijil, Linda M., Ducat, Sarah, Custers, Jerome, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Jacob-Dolan, Catherine, Lin, Zijin, Mahrokhian, Shant H., Nampanya, Felix, Nityanandam, Ramya, Pessaint, Laurent, Porto, Maciel, Ali, Vaneesha, Benetiene, Dalia, Tevi, Komlan, Andersen, Hanne, Lewis, Mark G., Schmidt, Aaron G., Lauffenburger, Douglas A., Alter, Galit, Estes, Jacob D., Schuitemaker, Hanneke, Zahn, Roland, Barouch, Dan H.

“…Coronavirus disease 2019 (COVID-19) in humans is often a clinically mild illness, but some individuals develop severe pneumonia, respiratory failure and death…”
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Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques by He, Xuan, Chandrashekar, Abishek, Zahn, Roland, Wegmann, Frank, Yu, Jingyou, Mercado, Noe B., McMahan, Katherine, Martinot, Amanda J., Piedra-Mora, Cesar, Beecy, Sidney, Ducat, Sarah, Chamanza, Ronnie, Huber, Sietske Rosendahl, van Heerden, Marjolein, van der Fits, Leslie, Borducchi, Erica N., Lifton, Michelle, Liu, Jinyan, Nampanya, Felix, Patel, Shivani, Peter, Lauren, Tostanoski, Lisa H., Pessaint, Laurent, Van Ry, Alex, Finneyfrock, Brad, Velasco, Jason, Teow, Elyse, Brown, Renita, Cook, Anthony, Andersen, Hanne, Lewis, Mark G., Schuitemaker, Hanneke, Barouch, Dan H.

“…We previously reported that a single immunization with an adenovirus serotype 26 (Ad26)-vector-based vaccine expressing an optimized SARS-CoV-2 spike…”
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Feasibility and safety of ultrasound-guided minimally invasive autopsy in COVID-19 patients by Brook, Olga R., Piper, Kimberly G., Mercado, Noe B., Gebre, Makda S., Barouch, Dan H., Busman-Sahay, Kathleen, Starke, Carly E., Estes, Jacob D., Martinot, Amanda J., Wrijil, Linda, Ducat, Sarah, Hecht, Jonathan L.

“…Objectives To determine the feasibility and safety of ultrasound-guided minimally invasive autopsy in COVID-19 patients. Methods 60 patients who expired…”
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Reduced SARS-CoV-2 disease outcomes in Syrian hamsters receiving immune sera: Quantitative image analysis in pathologic assessments by Piedra-Mora, Cesar, Robinson, Sally R., Tostanoski, Lisa H., Dayao, Denise A. E., Chandrashekar, Abishek, Bauer, Katherine, Wrijil, Linda, Ducat, Sarah, Hayes, Tammy, Yu, Jingyou, Bondzie, Esther A., McMahan, Katherine, Sellers, Daniel, Giffin, Victoria, Hope, David, Nampanya, Felix, Mercado, Noe B., Kar, Swagata, Andersen, Hanne, Tzipori, Saul, Barouch, Dan H., Martinot, Amanda J.

“…There is a need to standardize pathologic endpoints in animal models of SARS-CoV-2 infection to help benchmark study quality, improve cross-institutional…”
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Plasma Proteomics of COVID-19-Associated Cardiovascular Complications: Implications for Pathophysiology and Therapeutics by Roh, Jason D, Kitchen, Robert R, Guseh, J Sawalla, McNeill, Jenna N, Aid, Malika, Martinot, Amanda J, Yu, Andy, Platt, Colin, Rhee, James, Weber, Brittany, Trager, Lena E, Hastings, Margaret H, Ducat, Sarah, Xia, Peng, Castro, Claire, Singh, Abhilasha, Atlason, Bjarni, Churchill, Timothy W, Di Carli, Marcelo F, Ellinor, Patrick T, Barouch, Dan H, Ho, Jennifer E, Rosenzweig, Anthony

“…To gain insights into the mechanisms driving cardiovascular complications in COVID-19, we performed a case-control plasma proteomics study in COVID-19…”
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Plasma Proteomics of COVID-19–Associated Cardiovascular Complications by Roh, Jason D., Kitchen, Robert R., Guseh, J. Sawalla, McNeill, Jenna N., Aid, Malika, Martinot, Amanda J., Yu, Andy, Platt, Colin, Rhee, James, Weber, Brittany, Trager, Lena E., Hastings, Margaret H., Ducat, Sarah, Xia, Peng, Castro, Claire, Singh, Abhilasha, Atlason, Bjarni, Churchill, Timothy W., Di Carli, Marcelo F., Ellinor, Patrick T., Barouch, Dan H., Ho, Jennifer E., Rosenzweig, Anthony

“…[Display omitted] •Plasma proteomics identifies key biological processes associated with cardiac injury and stress in COVID-19.•Among 4,996 analytes measured,…”
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