Search Results - "Ducassou, Stephane"
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Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes
Published in Blood (04-07-2019)“…Evans syndrome (ES) is a rare severe autoimmune disorder characterized by the combination of autoimmune hemolytic anemia and immune thrombocytopenia. In most…”
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Single‐dose (4.5 mg/m2) gemtuzumab ozogamicin in combination with fludarabine, cytarabine and anthracycline as reinduction therapy in relapsed or refractory paediatric acute myeloid leukaemia
Published in British journal of haematology (01-07-2022)“…Summary Despite major therapeutic improvements, children with relapsed/refractory Acute Myeloid Leukaemia still have poor outcomes and overall survival does…”
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Rituximab in addition to LMB-based chemotherapy regimen in children and adolescents with primary mediastinal large B-cell lymphoma: results of the French LMB2001 prospective study
Published in Haematologica (Roma) (03-03-2022)“…Primary Mediastinal large B-cell Lymphoma (PMLBL) is a rare entity predominantly affecting adolescents and young adults. Recently, an international phase 2…”
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Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia
Published in Blood (05-12-2019)“…Chronic myeloid leukemia (CML) is rare in children and accounts for ≤15% of all myeloid leukemia cases. When we initiated this study with nilotinib, imatinib…”
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Neonatal Solid Tumors: Incidence and Survival in France
Published in Pediatric blood & cancer (01-08-2016)“…Background Solid tumors are uncommon in the neonatal period but represent an important cause of mortality and morbidity. Procedure Using the French National…”
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Is there still a place for serum galactomannan in the diagnosis of invasive aspergillosis in children at high risk and under antifungal prophylaxis?
Published in Mycoses (01-07-2024)“…Background The performance of serum galactomannan (GM) for the diagnosis of invasive aspergillosis (IA) has been studied mainly in adults. Paediatric data are…”
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Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL
Published in Blood (29-08-2024)“…•Chromothripsis, genomic complexity, gain at 6q27 (MLLT4) and del(16)(p13)/CREBBP are associated with a poor outcome in T-ALL.•Gain at 6q27 affecting MLLT4 is…”
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Germline pathogenic variants in transcription factors predisposing to pediatric acute myeloid leukemia: results from the French ELAM02 trial
Published in Haematologica (Roma) (01-03-2021)Get full text
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Prevalence and characteristics of metabolic syndrome in adults from the French childhood leukemia survivors' cohort: a comparison with controls from the French population
Published in Haematologica (Roma) (01-04-2018)“…The prevalence of the metabolic syndrome among adults from the French LEA childhood acute leukemia survivors' cohort was prospectively evaluated considering…”
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Clinical trial inclusion in patients with relapsed/refractory neuroblastoma following the European Precision Cancer Medicine trial MAPPYACTS
Published in European journal of cancer (1990) (01-04-2024)“…Despite poor survival for patients with relapsed or refractory neuroblastoma, only 10–16% of patients are reported to be included in early phase trials. This…”
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NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients
Published in Blood (10-10-2024)“…•NGS-based stratification refines risk classification in T-ALL.•NGS classifier combined with MRD and WBC identifies a group of patients with a very high risk…”
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Testosterone deficiency in men surviving childhood acute leukemia after treatment with hematopoietic stem cell transplantation or testicular radiation: an L.E.A. study
Published in Bone marrow transplantation (Basingstoke) (01-06-2021)“…We included 255 patients from the L.E.A. French long-term follow-up cohort. All had received hematopoietic stem cell transplantation (HSCT) and/or testicular…”
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Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias
Published in Blood (21-07-2022)“…Abstract Splenectomy is effective in ∼70% to 80% of pediatric chronic immune thrombocytopenia (cITP) cases, and few data exist about it in autoimmune hemolytic…”
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Enasidenib treatment in two individuals with D-2-hydroxyglutaric aciduria carrying a germline IDH2 mutation
Published in Nature Medicine (01-06-2023)“…D-2-hydroxyglutaric aciduria type II (D2HGA2) is a severe inborn disorder of metabolism caused by heterozygous R140 mutations in the IDH2 (isocitrate…”
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Adolescents and young adults with acute lymphoblastic leukemia. A specific management
Published in Bulletin du cancer (01-07-2017)“…The acute lymphoblastic leukemia (ALL) is one of the first cancer for which emerged the particularity of the adolescent and young adult population. After…”
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Second‐line treatment trends and long‐term outcomes of 392 children with chronic immune thrombocytopenic purpura: the French experience over the past 25 years
Published in British journal of haematology (01-06-2020)“…Summary Childhood chronic immune thrombocytopenic purpura (cITP) is a rare disease. In severe cases, there is no evidence for the optimal therapeutic strategy…”
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Outcome of childhood ALK-positive anaplastic large cell lymphoma relapses: Real-life experience of the French Society of Pediatric Oncology (SFCE) cohort of 75 French children
Published in Pediatric blood & cancer (21-10-2024)“…To describe treatments and outcomes of French children treated for relapsed/refractory anaplastic lymphoma kinase-positive anaplastic large cell lymphoma (ALK+…”
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Metabolic syndrome in long-term survivors of childhood acute leukemia treated without hematopoietic stem cell transplantation: an L.E.A. study
Published in Haematologica (Roma) (01-12-2016)“…Cardiovascular conditions are serious long-term complications of childhood acute leukemia. However, few studies have investigated the risk of metabolic…”
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Thrombopoietin receptor agonists as an emergency treatment for severe newly diagnosed immune thrombocytopenia in children
Published in Blood (07-01-2021)Get full text
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Expression of PD‐1/PD‐L1 in children's classical Hodgkin lymphomas
Published in Pediatric blood & cancer (01-05-2019)“…Background Although a prognosis of recurrent or refractory childhood Hodgkin lymphoma (HL) is associated with poor outcomes despite intensive therapy, the…”
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