Search Results - "Dubovetskyi, Artem"

Quinone Methide‐Based Organophosphate Hydrolases Inhibitors: Trans Proximity Labelers versus Cis Labeling Activity‐Based Probes by Dubovetskyi, Artem, Cherukuri, Kesava Phaneendra, Ashani, Yacov, Meshcheriakova, Anna, Reuveny, Eitan, Ben‐Nissan, Gili, Sharon, Michal, Fumagalli, Laura, Tawfik, Dan S.

“…Quinone methide (QM) chemistry is widely applied including in enzyme inhibitors. Typically, enzyme‐mediated bond breaking releases a phenol product that…”
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Diffusion of a disordered protein on its folded ligand by Wiggers, Felix, Wohl, Samuel, Dubovetskyi, Artem, Rosenblum, Gabriel, Zheng, Wenwei, Hofmann, Hagen

“…Intrinsically disordered proteins often form dynamic complexes with their ligands. Yet, the speed and amplitude of these motions are hidden in classical…”
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Diffusion of a disordered protein on its folded ligand by Hofmann, Hagen, Wiggers, Felix, Rosenblum, Gabriel, Dubovetskyi, Artem, Wohl, Samuel, Zheng, Wenwei

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Diffusion of a disordered protein on its folded ligand by Wiggers, Felix, Wohl, Samuel, Dubovetskyi, Artem, Rosenblum, Gabriel, Zheng, Wenwei, Hofmann, Hagen

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Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition by Ben-David, Moshe, Soskine, Misha, Dubovetskyi, Artem, Cherukuri, Kesava-Phaneendra, Dym, Orly, Sussman, Joel L, Liao, Qinghua, Szeler, Klaudia, Kamerlin, Shina Caroline Lynn, Tawfik, Dan S

“…Abstract Evolutionary trajectories are deemed largely irreversible. In a newly diverged protein, reversion of mutations that led to the functional switch…”
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A mixture of three engineered phosphotriesterases enables rapid detoxification of the entire spectrum of known threat nerve agents by Despotović, Dragana, Aharon, Einav, Dubovetskyi, Artem, Leader, Haim, Ashani, Yacov, Tawfik, Dan S

“…Abstract Nerve agents are organophosphates (OPs) that potently inhibit acetylcholinesterase, and their enzymatic detoxification has been a long-standing goal…”
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Utilization of diverse organophosphorus pollutants by marine bacteria by Despotović, Dragana, Aharon, Einav, Trofimyuk, Olena, Dubovetskyi, Artem, Cherukuri, Kesava Phaneendra, Ashani, Yacov, Eliason, Or, Sperfeld, Martin, Leader, Haim, Castelli, Andrea, Fumagalli, Laura, Savidor, Alon, Levin, Yishai, Longo, Liam M, Segev, Einat, Tawfik, Dan S

“…Anthropogenic organophosphorus compounds (AOPCs), such as phosphotriesters, are used extensively as plasticizers, flame retardants, nerve agents, and…”
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