Search Results - "Dubner, Allison"

Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodelling by Jolly, Austin J, Lu, Sizhao, Strand, Keith A, Dubner, Allison M, Mutryn, Marie F, Nemenoff, Raphael A, Majesky, Mark W, Moulton, Karen S, Weiser-Evans, Mary C M

“…Abstract Cardiovascular diseases are characterized by chronic vascular dysfunction and provoke pathological remodelling events, such as neointima formation,…”
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Confounding Effects of Tamoxifen: Cautionary and Practical Considerations for the Use of Tamoxifen-Inducible Mouse Models in Atherosclerosis Research-Brief Report by Dubner, Allison M, Lu, Sizhao, Jolly, Austin J, Noble, Tysen, Hinthorn, Tyler, Nemenoff, Raphael A, Moulton, Karen S, Majesky, Mark W, Weiser-Evans, Mary C M

“…In recent years, fate-mapping lineage studies in mouse models have led to major advances in vascular biology by allowing investigators to track specific cell…”
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High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling by Strand, Keith A., Lu, Sizhao, Mutryn, Marie F., Li, Linfeng, Zhou, Qiong, Enyart, Blake T., Jolly, Austin J., Dubner, Allison M., Moulton, Karen S., Nemenoff, Raphael A., Koch, Keith A., LaBarbera, Daniel V., Weiser-Evans, Mary C.M.

“…OBJECTIVE:Our recent work demonstrates that PTEN (phosphatase and tensin homolog) is an important regulator of smooth muscle cell (SMC) phenotype. SMC-specific…”
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Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis by Lu, Sizhao, Jolly, Austin J, Strand, Keith A, Dubner, Allison M, Mutryn, Marie F, Moulton, Karen S, Nemenoff, Raphael A, Majesky, Mark W, Weiser-Evans, Mary Cm

“…Resident vascular adventitial SCA1+ progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells…”
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Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis by Jolly, Austin J, Lu, Sizhao, Dubner, Allison M, Strand, Keith A, Mutryn, Marie F, Pilotti-Riley, Aaron, Danis, Etienne P, Nemenoff, Raphael A, Moulton, Karen S, Majesky, Mark W, Weiser-Evans, Mary Cm

“…Vascular smooth muscle-derived Sca1+ adventitial progenitor (AdvSca1-SM) cells are tissue-resident, multipotent stem cells that contribute to progression of…”
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Smooth muscle-derived adventitial progenitor cells direct atherosclerotic plaque composition complexity in a Klf4-dependent manner by Dubner, Allison M, Lu, Sizhao, Jolly, Austin J, Strand, Keith A, Mutryn, Marie F, Hinthorn, Tyler, Noble, Tysen, Nemenoff, Raphael A, Moulton, Karen S, Majesky, Mark W, Weiser-Evans, Mary Cm

“…We previously established that vascular smooth muscle-derived adventitial progenitor cells (AdvSca1-SM) preferentially differentiate into myofibroblasts and…”
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Sexually and Physically Abused Foster Care Children and Posttraumatic Stress Disorder by Dubner, Allison E, Motta, Robert W

“…Considerable debate exists regarding the possible relationship between child abuse and posttraumatic stress disorder (PTSD). In this study, 3 groups of foster…”
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4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis by Dubner, Allison Milfred, Lu, Sizhao, Jolly, Austin, Strand, Keith, Mutryn, Marie, Tucker, Rebecca, Moulton, Karen, Nemenoff, Raphael A., Weiser-Evans, Mary C.M.

“…OBJECTIVES/GOALS: Our lab previously identified a population of vascular smooth muscle (SMC)-derived progenitor cells (AdvSca1-SM) which expand robustly in…”
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Abstract 363: Resident Vascular Adventitial Progenitor Cells Of Smooth Muscle Cell-lineage Adopt Profibrotic Phenotype And Contribute To Cardiac Fibrosis by Lu, Sizhao, Dubner, Allison, Jolly, Austin, Noble, Tysen, Nemenoff, Raphael, Moulton, Karen, Weiser-Evans, Mary C

“…Abstract only Cardiac myofibroblasts are the major contributors to ECM deposition in pathological cardiovascular fibrosis, which is the characteristic feature…”
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Abstract 651: The Chromatin Remodeler Brg1 Drives Adventitial Progenitor Cell Myofibroblast Differentiation And Vascular Fibrosis by Jolly, Austin, Lu, Sizhao, Dubner, Allison, Noble, Tysen, Weiser-Evans, Mary C

“…Abstract only Cardiovascular diseases lead to stiffening of blood vessels. We identified a population of smooth muscle-derived progenitor cells that reside in…”
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Abstract 688: PTEN Protects Against Vascular Smooth Muscle Cell Pro-inflammatory Dedifferentiation Through Metabolic Rewiring by Lu, Sizhao, Jolly, Austin, Dubner, Allison, Noble, Tysen, Nemenoff, Raphael, Moulton, Karen, Weiser-Evans, Mary C

“…Abstract only Vascular smooth muscle cells (SMCs) play a critical role in intimal hyperplasia in atherosclerosis and restenosis. SMCs in diseased arteries…”
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Abstract 208: The Chromatin Remodeling Protein Brg1 Regulates Adventitial Progenitor Cell Myofibroblast Differentiation And Pathological Vascular Remodeling by Jolly, Austin, Lu, Sizhao, Dubner, Allison, Mutryn, Marie, Navarro, Natalie, Nemenoff, Raphael, Weiser-Evans, Mary C

“…Cardiovascular diseases lead to long-term stiffening of arteries and small vessels. The vascular wall contains several cellular populations that coordinate to…”
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Abstract 109: The Chromatin Remodeling Protein Brg1 Regulates Adventitial Progenitor Cell Myofibroblast Differentiation And Pathological Vascular Remodeling by Jolly, Austin, Lu, Sizhao, Dubner, Allison, Mutryn, Marie, Navarro, Natalie, Nemenoff, Raphael, Weiser-Evans, Mary C

“…Cardiovascular diseases lead to long-term stiffening of arteries and small vessels. The vascular wall contains several cellular populations that coordinate to…”
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Contribution of smooth muscle-derived vascular progenitor cells to atherosclerosis by Dubner, Allison, Lu, Sizhao, Jolly, Austin, Noble, Tysen, Moulton, Karen, Nemenoff, Raphael, Weiser-Evans, Mary

“…Abstract only Purpose: Atherosclerosis is a major cause of morbidity and mortality worldwide, but current therapies fail to adequately meet clinical needs…”
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Abstract 452: Contribution Of Smooth Muscle-derived Vascular Progenitor Cells To Atherosclerosis by Dubner, Allison M, Lu, Sizhao, Jolly, Austin, Noble, Tysen, Nemenoff, Raphael, Moulton, Karen, Weiser-Evans, Mary C

“…Abstract only Purpose: Atherosclerosis is a major cause of morbidity and mortality worldwide, but current therapies fail to adequately meet clinical needs. Our…”
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Abstract 2150: PTEN Protects Against Vascular Smooth Muscle Cell Pro-inflammatory Dedifferentiation Through Metabolic Re-wiring by Lu, Sizhao, Dubner, Allison M, Jolly, Austin J, Noble, Tysen D, Hinthorn, Tyler, Nemenoff, Raphael A, Moulton, Karen S, Weiser-Evans, Mary C

“…Abstract only Vascular smooth muscle cells (SMCs) play a critical role in intimal hyperplasia in atherosclerosis and restenosis. SMCs in diseased arteries…”
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Abstract 2149: Smooth Muscle-derived Resident Vascular Adventitial Progenitor Cell Contribution To Cardiac Fibrosis And Inflammation Is Dependent On KLF4 by Lu, Sizhao, Dubner, Allison M, Jolly, Austin J, Noble, Tysen D, Hinthorn, Tyler, Nemenoff, Raphael A, Moulton, Karen S, Weiser-Evans, Mary C

“…Abstract only Cardiac fibrosis is defined by the excessive accumulation of extracellular matrix (ECM) material resulting in cardiac tissue scarring and…”
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Confounding effects of tamoxifen: cautionary and practical considerations for the use of tamoxifen-inducible mouse models in atherosclerosis research by Dubner, Allison M, Lu, Sizhao, Jolly, Austin J, Noble, Tysen, Hinthorn, Tyler, Nemenoff, Raphael A, Moulton, Karen S, Majesky, Mark W, Weiser-Evans, Mary CM

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Abstract MP12: The Epigenetic Remodeling Protein Brg1 Is Implicated In Vascular Progenitor Cell Contribution To Pathological Vascular Remodeling And Fibrosis by Jolly, Austin, Lu, Sizhao, Dubner, Allison, Strand, Keith, Mutryn, Marie, Moulton, Karen, Nemenoff, Raphael, Weiser-Evans, Mary

“…Abstract only Vascular fibrosis is an irreversible consequence of vascular remodeling that ensues in many cardiovascular diseases. Currently, no treatments are…”
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One-Hour Esophageal String Test: A Nonendoscopic Minimally Invasive Test That Accurately Detects Disease Activity in Eosinophilic Esophagitis by Ackerman, Steven J., Kagalwalla, Amir F., Hirano, Ikuo, Gonsalves, Nirmala, Katcher, Paul Menard, Gupta, Sandeep, Wechsler, Joshua B., Grozdanovic, Milica, Pan, Zhaoxing, Masterson, Joanne C., Du, Jian, Fantus, Robert J., Alumkal, Preeth, Lee, James J., Ochkur, Sergei, Ahmed, Faria, Capocelli, Kelley, Melin-Aldana, Hector, Biette, Kathryn, Dubner, Allison, Amsden, Katie, Keeley, Kaitlin, Sulkowski, Maureen, Zalewski, Angelika, Atkins, Dan, Furuta, Glenn T.

“…Eosinophilic esophagitis (EoE), a chronic food allergic disease, lacks sensitive and specific peripheral biomarkers. We hypothesized that levels of EoE-related…”
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