Search Results - "Dubinin, Mikhail V."

Diabetes Mellitus, Mitochondrial Dysfunction and Ca2+-Dependent Permeability Transition Pore by Belosludtsev, Konstantin N., Belosludtseva, Natalia V., Dubinin, Mikhail V.

“…Diabetes mellitus is one of the most common metabolic diseases in the developed world, and is associated either with the impaired secretion of insulin or with…”
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Ion Channels of the Sarcolemma and Intracellular Organelles in Duchenne Muscular Dystrophy: A Role in the Dysregulation of Ion Homeostasis and a Possible Target for Therapy by Dubinin, Mikhail V, Belosludtsev, Konstantin N

“…Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein and a properly functioning dystrophin-associated protein complex (DAPC) in…”
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Effect of VBIT-4 on the functional activity of isolated mitochondria and cell viability by Belosludtsev, Konstantin N., Ilzorkina, Anna I., Matveeva, Lyudmila A., Chulkov, Alexander V., Semenova, Alena A., Dubinin, Mikhail V., Belosludtseva, Natalia V.

“…VBIT-4 is a new inhibitor of the oligomerization of VDAC proteins of the outer mitochondrial membrane preventing the development of oxidative stress,…”
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Alisporivir Improves Mitochondrial Function in Skeletal Muscle of mdx Mice but Suppresses Mitochondrial Dynamics and Biogenesis by Dubinin, Mikhail V, Starinets, Vlada S, Talanov, Eugeny Yu, Mikheeva, Irina B, Belosludtseva, Natalia V, Belosludtsev, Konstantin N

“…Mitigation of calcium-dependent destruction of skeletal muscle mitochondria is considered as a promising adjunctive therapy in Duchenne muscular dystrophy…”
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An in vivo study of the toxic effects of triclosan on Xenopus laevis (Daudin, 1802) frog: Assessment of viability, tissue damage and mitochondrial dysfunction by Tenkov, Kirill S., Dubinin, Mikhail V., Vedernikov, Alexander A., Chelyadnikova, Yuliya A., Belosludtsev, Konstantin N.

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The Effect of Deflazacort Treatment on the Functioning of Skeletal Muscle Mitochondria in Duchenne Muscular Dystrophy by Dubinin, Mikhail V, Talanov, Eugeny Yu, Tenkov, Kirill S, Starinets, Vlada S, Belosludtseva, Natalia V, Belosludtsev, Konstantin N

“…Duchenne muscular dystrophy (DMD) is a severe hereditary disease caused by a lack of dystrophin, a protein essential for myocyte integrity. Mitochondrial…”
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A Comparative Study of the Action of Protonophore Uncouplers and Decoupling Agents as Inducers of Free Respiration in Mitochondria in States 3 and 4: Theoretical and Experimental Approaches by Samartsev, Victor N., Semenova, Alena A., Dubinin, Mikhail V.

“…Theoretical and experimental studies have revealed that that in the liver mitochondria an increase in the rate of free respiration in state 3 induced by…”
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Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet-Streptozotocin-Induced Diabetes by Belosludtseva, Natalia V, Starinets, Vlada S, Mikheeva, Irina B, Belosludtsev, Maxim N, Dubinin, Mikhail V, Mironova, Galina D, Belosludtsev, Konstantin N

“…Long-term hyperglycemia in diabetes mellitus is associated with complex damage to cardiomyocytes and the development of mitochondrial dysfunction in the…”
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Alisporivir Treatment Alleviates Mitochondrial Dysfunction in the Skeletal Muscles of C57BL/6NCrl Mice with High-Fat Diet/Streptozotocin-Induced Diabetes Mellitus by Belosludtsev, Konstantin N, Starinets, Vlada S, Talanov, Eugeny Yu, Mikheeva, Irina B, Dubinin, Mikhail V, Belosludtseva, Natalia V

“…Diabetes mellitus is a systemic metabolic disorder associated with mitochondrial dysfunction, with mitochondrial permeability transition (MPT) pore opening…”
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The Effect of Uridine on the State of Skeletal Muscles and the Functioning of Mitochondria in Duchenne Dystrophy by Dubinin, Mikhail V., Starinets, Vlada S., Belosludtseva, Natalia V., Mikheeva, Irina B., Chelyadnikova, Yuliya A., Penkina, Daria K., Vedernikov, Alexander A., Belosludtsev, Konstantin N.

“…Duchenne muscular dystrophy is caused by the loss of functional dystrophin that secondarily causes systemic metabolic impairment in skeletal muscles and…”
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Reduction of Mitochondrial Calcium Overload via MKT077-Induced Inhibition of Glucose-Regulated Protein 75 Alleviates Skeletal Muscle Pathology in Dystrophin-Deficient mdx Mice by Dubinin, Mikhail V, Stepanova, Anastasia E, Mikheeva, Irina B, Igoshkina, Anastasia D, Cherepanova, Alena A, Talanov, Eugeny Yu, Khoroshavina, Ekaterina I, Belosludtsev, Konstantin N

“…Duchenne muscular dystrophy is secondarily accompanied by Ca excess in muscle fibers. Part of the Ca accumulates in the mitochondria, contributing to the…”
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Modulators reducing the efficiency of oxidative ATP synthesis in mitochondria: protonophore uncouplers, cyclic redox agents, and decouplers by Samartsev, Victor N., Semenova, Alena A., Belosludtsev, Konstantin N., Dubinin, Mikhail V.

“…This work considers the main indicators of the oxidative phosphorylation efficiency in mitochondria: the ADP/O and H + /O ratios. Three groups of modulators…”
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Effect of Triclosan on the Functioning of Liver Mitochondria and Permeability of Erythrocyte Membranes of Marsh Frog (Pelophylax ridibundus (Pallas, 1771)) by Dubinin, Mikhail V., Tenkov, Kirill S., Svinin, Anton O., Samartsev, Victor N., Belosludtsev, Konstantin N.

“…The paper examines the effects of the antimicrobial agent triclosan on the functioning of the liver mitochondria of marsh frog ( Pelophylax ridibundus (Pallas,…”
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Effect of F16-Betulin Conjugate on Mitochondrial Membranes and Its Role in Cell Death Initiation by Dubinin, Mikhail V., Semenova, Alena A., Nedopekina, Darya A., Davletshin, Eldar V., Spivak, Anna Yu, Belosludtsev, Konstantin N.

“…This work demonstrates the effects of a newly synthesized conjugate of the plant triterpenoid betulin and the penetrating cation F16 used for mitochondrial…”
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Synthesis of a Novel, Biocompatible and Bacteriostatic Borosiloxane Composition with Silver Oxide Nanoparticles by Chausov, Denis N, Smirnova, Veronika V, Burmistrov, Dmitriy E, Sarimov, Ruslan M, Kurilov, Alexander D, Astashev, Maxim E, Uvarov, Oleg V, Dubinin, Mikhail V, Kozlov, Valery A, Vedunova, Maria V, Rebezov, Maksim B, Semenova, Anastasia A, Lisitsyn, Andrey B, Gudkov, Sergey V

“…Microbial antibiotic resistance is an important global world health problem. Recently, an interest in nanoparticles (NPs) of silver oxides as compounds with…”
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BKCa Activator NS1619 Improves the Structure and Function of Skeletal Muscle Mitochondria in Duchenne Dystrophy by Dubinin, Mikhail V., Starinets, Vlada S., Belosludtseva, Natalia V., Mikheeva, Irina B., Chelyadnikova, Yuliya A., Igoshkina, Anastasia D., Vafina, Aliya B., Vedernikov, Alexander A., Belosludtsev, Konstantin N.

“…Duchenne muscular dystrophy (DMD) is a progressive hereditary disease caused by the absence of the dystrophin protein. This is secondarily accompanied by a…”
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Mitochondrial Transplantation Therapy Ameliorates Muscular Dystrophy in mdx Mouse Model by Dubinin, Mikhail V, Mikheeva, Irina B, Stepanova, Anastasia E, Igoshkina, Anastasia D, Cherepanova, Alena A, Semenova, Alena A, Sharapov, Vyacheslav A, Kireev, Igor I, Belosludtsev, Konstantin N

“…Duchenne muscular dystrophy is caused by loss of the dystrophin protein. This pathology is accompanied by mitochondrial dysfunction contributing to muscle…”
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ANT-Mediated Inhibition of the Permeability Transition Pore Alleviates Palmitate-Induced Mitochondrial Dysfunction and Lipotoxicity by Belosludtseva, Natalia V, Ilzorkina, Anna I, Serov, Dmitriy A, Dubinin, Mikhail V, Talanov, Eugeny Yu, Karagyaur, Maxim N, Primak, Alexandra L, Liu, Jiankang, Belosludtsev, Konstantin N

“…Hyperlipidemia is a major risk factor for vascular lesions in diabetes mellitus and other metabolic disorders, although its basis remains poorly understood…”
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Effect of the MPT Pore Inhibitor Alisporivir on the Development of Mitochondrial Dysfunction in the Heart Tissue of Diabetic Mice by Belosludtseva, Natalia V., Starinets, Vlada S., Mikheeva, Irina B., Serov, Dmitriy A., Astashev, Maxim E., Belosludtsev, Maxim N., Dubinin, Mikhail V., Belosludtsev, Konstantin N.

“…Diabetes mellitus is a systemic metabolic disorder associated with mitochondrial dysfunction, with the mitochondrial permeability transition (MPT) pore opening…”
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Bile Acids as Inducers of Protonophore and Ionophore Permeability of Biological and Artificial Membranes by Samartsev, Victor N, Khoroshavina, Ekaterina I, Pavlova, Evgeniya K, Dubinin, Mikhail V, Semenova, Alena A

“…It is now generally accepted that the role of bile acids in the organism is not limited to their participation in the process of food digestion. Indeed, bile…”
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