Search Results - "Dubey, Praveen"

Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart by Dubey, Praveen K, Dubey, Shubham, Singh, Sarojini, Bhat, Purnima Devaki, Pogwizd, Steven, Krishnamurthy, Prasanna

“…Obg-like ATPase 1 (OLA1) protein has GTP and ATP hydrolyzing activities and is important for cellular growth and survival. The human OLA1 gene maps to…”
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Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover by Martin, Thomas G., Myers, Valerie D., Dubey, Praveen, Dubey, Shubham, Perez, Edith, Moravec, Christine S., Willis, Monte S., Feldman, Arthur M., Kirk, Jonathan A.

“…The association between reduced myofilament force-generating capacity (F max ) and heart failure (HF) is clear, however the underlying molecular mechanisms are…”
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Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice by Dubey, Praveen K., Patil, Mallikarjun, Singh, Sarojini, Dubey, Shubham, Ahuja, Paras, Verma, Suresh Kumar, Krishnamurthy, Prasanna

“…Endotoxemia triggers life-threatening immune and cardiovascular response that leads to tissue damage, multi-organ failure, and death. The understanding of…”
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Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart by Patil, Mallikarjun, Saheera, Sherin, Dubey, Praveen K., Kahn-Krell, Asher, Kumar Govindappa, Prem, Singh, Sarojini, Tousif, Sultan, Zhang, Qinkun, Lal, Hind, Zhang, Jianyi, Qin, Gangjian, Krishnamurthy, Prasanna

“…[Figure: see text]…”
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TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a by Nyati, Kishan K, Masuda, Kazuya, Zaman, Mohammad Mahabub-Uz, Dubey, Praveen K, Millrine, David, Chalise, Jaya P, Higa, Mitsuru, Li, Songling, Standley, Daron M, Saito, Kazunobu, Hanieh, Hamza, Kishimoto, Tadamitsu

“…The AT-rich interactive domain-containing protein 5a (Arid5a) plays a critical role in autoimmunity by regulating the half-life of Interleukin-6 (IL-6) mRNA…”
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MicroRNA-181c-5p modulates phagocytosis efficiency in bone marrow-derived macrophages by Singh, Sarojini, Henderson, John, Patil, Mallikarjun, Dubey, Praveen K., Dubey, Shubham, Kannappan, Ramaswamy, Zhang, Jianyi, Krishnamurthy, Prasanna

“…Objective and design Phagocytosis and clearance of apoptotic cells are essential for inflammation resolution, efficient wound healing, and tissue homeostasis…”
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Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts by Dubey, Shubham, Dubey, Praveen K., Umeshappa, Channakeshava S., Ghebre, Yohannes T., Krishnamurthy, Prasanna

“…Pathological fibrosis contributes to progression of various diseases, for which the therapeutic options are limited. Idiopathic pulmonary fibrosis (IPF) is one…”
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The aryl hydrocarbon receptor/microRNA-212/132 axis in T cells regulates IL-10 production to maintain intestinal homeostasis by Chinen, Ichino, Nakahama, Taisuke, Kimura, Akihiro, Nguyen, Nam T, Takemori, Hiroshi, Kumagai, Ayako, Kayama, Hisako, Takeda, Kiyoshi, Lee, Soyoung, Hanieh, Hamza, Ripley, Barry, Millrine, David, Dubey, Praveen K, Nyati, Kishan K, Fujii-Kuriyama, Yoshiaki, Chowdhury, Kamal, Kishimoto, Tadamitsu

“…Aryl hydrocarbon receptor (Ahr), a transcription factor, plays a critical role in autoimmune inflammation of the intestine. In addition, microRNAs (miRNAs),…”
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Current Landscape of Heart Failure Gene Therapy by Kieserman, Jake M, Myers, Valerie D, Dubey, Praveen, Cheung, Joseph Y, Feldman, Arthur M

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Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblon via suppression of the TRIF/IRF3 pathway by Millrine, David, Miyata, Haruhiko, Tei, Mami, Dubey, Praveen, Nyati, Kishan, Nakahama, Taisuke, Gemechu, Yohannes, Ripley, Barry, Kishimoto, Tadamitsu

“…Thalidomide and its derivatives, collectively referred to as immunomodulatory drugs (IMiDs), are effective inhibitors of inflammation and are known to inhibit…”
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Askin's tumor - A dual case study of rare thoracic neoplasm by Vinay, V, Dubey, Praveen, Singh, Kuljeet, Saini, Jitendra, Iyer, Srinath, Srivastava, Alpana

“…Askin's tumor is a primitive neuroectodermal tumor (PNET) that belongs to the class of small round cell malignant tumor. It has a poor survival rate as it is…”
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Arid5a-deficient mice are highly resistant to bleomycin-induced lung injury by Dubey, Praveen Kumar, Masuda, Kazuya, Nyati, Kishan Kumar, -Uz Zaman, Mohammad Mahabub, Chalise, Jaya Prakash, Millrine, David, Kai, Wang, Ripley, Barry, Kishimoto, Tadamitsu

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are among the major causes of death worldwide due to acute inflammation in the lung…”
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Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants by Martin, Thomas G, Pak, Hana, Gerhard, Glenn S, Merali, Salim, Merali, Carmen, Lemster, Bonnie, Dubey, Praveen, McTiernan, Charles F, Bristow, Michael R, Feldman, Arthur M, Kirk, Jonathan A

“…Mutations to the co-chaperone protein BAG3 (B-cell lymphoma-2-associated athanogene-3) are a leading cause of dilated cardiomyopathy (DCM). These mutations…”
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Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart by Wang, JuFang, Tomar, Dhadendra, Martin, Thomas G., Dubey, Shubham, Dubey, Praveen K., Song, Jianliang, Landesberg, Gavin, McCormick, Michael G., Myers, Valerie D., Merali, Salim, Merali, Carmen, Lemster, Bonnie, McTiernan, Charles F., Khalili, Kamel, Madesh, Muniswamy, Cheung, Joseph Y., Kirk, Jonathan A., Feldman, Arthur M.

“…[Display omitted] •Mice with heterozygous knockout of Bag3 are phenotypically normal by echocardiography at 8 to 10 weeks of age but show marked changes in…”
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microRNA-377 Signaling Modulates Anticancer Drug-Induced Cardiotoxicity in Mice by Henderson, John, Dubey, Praveen K, Patil, Mallikarjun, Singh, Sarojini, Dubey, Shubham, Namakkal Soorappan, Rajasekaran, Kannappan, Ramaswamy, Sethu, Palaniappan, Qin, Gangjian, Zhang, Jianyi, Krishnamurthy, Prasanna

“…Doxorubicin (DOX, an anthracycline) is a widely used chemotherapy agent against various forms of cancer; however, it is also known to induce dose-dependent…”
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RGD modified albumin nanospheres for tumour vasculature targeting by Dubey, Praveen K., Singodia, Deepak, Verma, Rahul K., Vyas, Suresh P.

“…Objectives  Cyclic arginine‐glycine‐aspartic acid (RGD) peptide‐anchored sterically stabilized albumin nanospheres (RGD‐SN) have been investigated for the…”
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Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17–producing T-helper cell differentiation by Nakahama, Taisuke, Hanieh, Hamza, Nguyen, Nam Trung, Chinen, Ichino, Ripley, Barry, Millrine, David, Lee, Soyoung, Nyati, Kishan Kumar, Dubey, Praveen Kumar, Chowdhury, Kamal, Kawahara, Yukio, Kishimoto, Tadamitsu

“…Aryl hydrocarbon receptor (AHR) plays critical roles in various autoimmune diseases such as multiple sclerosis by controlling interleukin-17 (IL-17)–producing…”
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Evaluation of therapeutic potential of recombinant buffalo lactoferrin N-lobe expressed in E. coli by Kumari, Namita, Kumar, Arun, Goyal, Shubham, Dubey, Praveen K., Mishra, Shailendra K., Ahlawat, Sonika, Kataria, Ranjit. S.

“…Lactoferrin (Lf) is a multifunctional bi-lobate iron-binding glycoprotein belonging to transferrin family with a mass of approximately 80 kD. Being…”
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A conformational analysis of mouse Nalp3 domain structures by molecular dynamics simulations, and binding site analysis by Sahoo, Bikash R, Maharana, Jitendra, Bhoi, Gopal K, Lenka, Santosh K, Patra, Mahesh C, Dikhit, Manas R, Dubey, Praveen K, Pradhan, Sukanta K, Behera, Bijay K

“…Scrutinizing various nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) genes in higher eukaryotes is very important for understanding the…”
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Assessing the effectiveness and safety of transbronchial lung cryobiopsy utilizing a flexible bronchoscope with an endobronchial blocker in diffuse parenchymal lung lesions by Sharma, Deepak, V, Vinay, Saini, Jitendra Kumar, Sethi, Prabhpreet, Kumar, Lokender, Dubey, Praveen Kumar

“…Transbronchial lung cryobiopsy (TBLC) with flexible bronchoscope represents an encouraging modality to obtain a larger size specimen without crush artifact,…”
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