Search Results - "Dubedat, P"

Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study by Benazzouz, Abdelhamid, Boraud, Thomas, Dubédat, Pierre, Boireau, Alain, Stutzmann, Jean-Marie, Gross, Christian

“…Previous studies have shown that riluzole (2-amino-6-trifluoromethoxy-benzothiazole), a drug which interferes with glutamate neurotransmission, has a…”
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The protective effect of riluzole in the MPTP model of Parkinson's disease in mice is not due to a decrease in MPP + accumulation by Boireau, A, Dubedat, P, Bordier, F, Imperato, A, Moussaoui, S

“…Riluzole, has previously been shown to be protective in animal models of Parkinson's disease in vivo. In the present study the effects of riluzole on the…”
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Effects of complete and partial lesions of the dopaminergic mesotelencephalic system on skilled forelimb use in the rat by Barnéoud, P., Parmentier, S., Mazadier, M., Miquet, J.M., Boireau, A., Dubédat, P., Blanchard, J.-C.

“…This study compares certain behavioural consequences of partial and complete unilateral lesions of the dopaminergic mesotelencephalic system. We investigated…”
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Riluzole and experimental parkinsonism: antagonism of MPTP-induced decrease in central dopamine levels in mice by Boireau, A, Dubédat, P, Bordier, F, Peny, C, Miquet, J M, Durand, G, Meunier, M, Doble, A

“…We have investigated whether riluzole, a compound that interferes with glutamatergic (GLUergic) transmission, would protect central dopaminergic (DAergic)…”
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Riluzole and experimental parkinsonism: partial antagonism of MPP(+)-induced increase in striatal extracellular dopamine in rats in vivo by Boireau, A, Miquet, J M, Dubédat, P, Meunier, M, Doble, A

“…Superfusion of the rat striatum with 100 microM of 1-methyl-4-phenylpyridinium (MPP+) induced a 70-fold increase in dopamine (DA) release and a decrease in the…”
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Methamphetamine and dopamine neurotoxicity: differential effects of agents interfering with glutamatergic transmission by Boireau, Alain, Bordier, Frangoise, Dubédat, Pierre, Doble, Adam

“…The effects of riluzole and lamotrigine, two agents which interfere with the release of glutamate (GLU), and MK-801, a blocker of N-methyl- d-aspartate (NMDA)…”
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Neuroprotective effects of riluzole on a model of parkinson's disease in the rat by Barnéoud, P., Mazadier, M., Miquet, J.-M., Parmentier, S., Dubédat, P., Doble, A., Boireau, A.

“…The aim of the present study was to analyse whether riluzole, a compound that interacts with the voltage-dependent sodium channel and impairs glutamatergic…”
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Neurotensin effects on evoked release of dopamine in slices from striatum, nucleus accumbens and prefrontal cortex in rat by HETIER, E, BOIREAU, A, DUBEDAT, P, BLANCHARD, J. C

“…The effects of neurotensin (NT) on the K+-evoked release of endogenous and tritiated dopamine in striatum and on 3H-dopamine in slices from nucleus accumbens…”
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Identification of intact neurotensin in the substantia nigra after its retrograde axonal transport in dopaminergic neurons by Castel, M N, Faucher, D, Cuiné, F, Dubédat, P, Boireau, A, Laduron, P M

“…Two hours after the injection of (3-[125I]iodotyrosyl3) neurotensin into the striatum, a labeling was observed in the ipsilateral substantia nigra. In the…”
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Preferential decrease in dopamine utilization in prefrontal cortex by zopiclone, diazepam and zolpidem in unstressed rats by Boireau, A, Dubedat, P, Laduron, P M, Doble, A, Blanchard, J C

“…This study has compared the effects of a cyclopyrrolone, zopiclone, a benzodiazepine, diazepam, and an imidazopyridine, zolpidem, on dopamine (DA) and DOPAC…”
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Differential effects of potassium channel blockers on dopamine release from rat striatal slices by Boireau, A, Richard, F, Olivier, V, Aubeneau, M, Miquet, J M, Dubédat, P, Laduron, P, Doble, A, Blanchard, J C

“…The effects of different potassium channel blockers on tritiated dopamine [( 3H]DA) release were investigated in rat striatal slices in the presence of…”
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Thalidomide reduces MPTP-induced decrease in striatal dopamine levels in mice by Boireau, Alain, Bordier, Françoise, Dubédat, Pierre, Pény, Colette, Impérato, Assunta

“…The effects of thalidomide, a sedative, anti-inflammatory and immunosuppressive agent were studied in the MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)…”
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The anti-oxidant ebselen antagonizes the release of the apoptogenic factor cytochrome c induced by Fe2+/citrate in rat liver mitochondria by BOIREAU, A, MARECHAL, P.-A, MEUNIER, M, DUBEDAT, P, MOUSSAOUI, S

“…We studied the effects of ebselen (a seleno-organic anti-oxidant), on the release of the apoptogenic factor, cytochrome c, in two different experimental…”
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The protective effect of riluzole in the MPTP model of Parkinson's disease in mice is not due to a decrease in MPP super(+) accumulation by Boireau, A, Dubedat, P, Bordier, F, Imperato, A, Moussaoui, S

“…Riluzole, has previously been shown to be protective in animal models of Parkinson's disease in vivo. In the present study the effects of riluzole on the…”
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Effects of Ebselen, a Glutathione Peroxidase Mimic, in Several Models of Mitochondrial Dysfunction by BOIREAU, ALAIN, DUBEDAT, PIERRE, BORDIER, FRANÇOISE, COIMBRA, MADELEINE, MEUNIER, MIREILLE, IMPERATO, ASSUNTA, MOUSSAOUI, SALIHA

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The anti-oxidant ebselen antagonizes the release of the apoptogenic factor cytochrome c induced by Fe super(2+)/citrate in rat liver mitochondria by Boireau, A, Marechal, P-A, Meunier, M, Dubedat, P, Moussaoui, S

“…We studied the effects of ebselen (a seleno-organic anti-oxidant), on the release of the apoptogenic factor, cytochrome c, in two different experimental…”
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In vivo determination of the profile of benzodiazepine ligands by comparing the inhibition of 3H-Ro 15-1788 binding to the modulation of cGMP levels in mouse cerebellum by Boireau, A, Martel, M, Farges, G, Dubédat, P, Laduron, P M, Blanchard, J C

“…The in vivo effects of various benzodiazepine (BZD) ligands belonging to different chemical families were studied comparatively in mouse cerebellum using…”
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Enhancing effect of dopamine blockers on evoked acetylcholine release in rat striatal slices: a classical D-2 antagonist response? by Boireau, A, Chambry, J, Dubedat, P, Farges, G, Carruette, A M, Zundel, J L, Blanchard, J C

“…The effects of chlorpromazine, pipotiazine, haloperidol, domperidone, sulpiride and SCH 23390 on the potassium-evoked release of [3H]acetylcholine [( 3H]ACh)…”
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Effects of lethal overexposure on gastric secretion in the pig by Rémy, J, Daburon, F, Villiers, P A, Dubedat, P

“…The characteristics of gastric secretion following acute gamma exposure (1500 rd) were studied in pigs with a small Pavlov stomach. Spontaneous secretion was…”
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