Search Results - "Dube, M P"

Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations by Goldberg, YP, MacFarlane, J, MacDonald, ML, Thompson, J, Dube, M-P, Mattice, M, Fraser, R, Young, C, Hossain, S, Pape, T, Payne, B, Radomski, C, Donaldson, G, Ives, E, Cox, J, Younghusband, HB, Green, R, Duff, A, Boltshauser, E, Grinspan, GA, Dimon, JH, Sibley, BG, Andria, G, Toscano, E, Kerdraon, J, Bowsher, D, Pimstone, SN, Samuels, ME, Sherrington, R, Hayden, MR

“…Congenital indifference to pain (CIP) is a rare condition in which patients have severely impaired pain perception, but are otherwise essentially normal. We…”
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Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent by Aminkeng, F, Ross, C J D, Rassekh, S R, Brunham, L R, Sistonen, J, Dube, M-P, Ibrahim, M, Nyambo, T B, Omar, S A, Froment, A, Bodo, J-M, Tishkoff, S, Carleton, B C, Hayden, M R

“…There is established clinical evidence for differences in drug response, cure rates and survival outcomes between different ethnic populations, but the causes…”
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Preliminary Guidelines for the Evaluation and Management of Dyslipidemia in Adults Infected with Human Immunodeficiency Virus and Receiving Antiretroviral Therapy: Recommendations of the Adult AIDS Clinical Trial Group Cardiovascular Disease Focus Group by Mayer, Kenneth H., Dubé, Michael P., Sprecher, Dennis, Henry, W. Keith, Aberg, Judith A., Torriani, Francesca J., Hodis, Howard N., Schouten, Jeffrey, Levin, Jules, Myers, Gary, Zackin, Robert, Nevin, Thomas, Currier, Judith S.

“…Dyslipidemia is a prevalent condition that affects patients infected with human immunodeficiency virus (HIV) who are receiving antiretroviral therapy. These…”
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Disorders of Glucose Metabolism in Patients Infected with Human Immunodeficiency Virus by DUBE, Michael P

“…New-onset diabetes mellitus, clinically similar to type 2 diabetes, will affect a small proportion (1%–6%) of patients infected with human immunodeficiency…”
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The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response by HAUBRICH, R. H, LITTLE, S. J, CURRIER, J. S, FORTHAL, D. N, KEMPER, C. A, BEALL, G. N, JOHNSON, D, DUBE, M. P, HWANG, J. Y, MCCUTCHAN, J. A

“…Objective: To correlate self-reported antiretroviral adherence with virologic suppression. Design: Prospective observational study of adherence to therapy…”
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Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1 by Fortin, A., Diez, E., Ritchie, J., Sotocinal, S. G., Dube, M.‐P., Gagne, M., Paquette, O., Skamene, E., Mogil, J. S.

“…To identify novel pain‐relevant genes, a set of 35 recombinant congenic strains derived from the sensitive C57BL/6 and resistant A/J strains were tested for…”
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Low genetic variability of Striga gesnerioides populations parasitic on cowpea might be explained by a recent origin by DUBE, M-P, BELZILE, F.J

“…Striga gesnerioides is an obligate root hemiparasitic plant that causes considerable yield losses to cowpea, an important crop legume of Sub-Saharan Africa…”
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Effects of Potent Antiretroviral Therapy on Free Testosterone Levels and Fat-Free Mass in Men in a Prospective, Randomized Trial: A5005s, a Substudy of AIDS Clinical Trials Group Study 384 by Dubé, Michael P., Parker, Robert A., Mulligan, Kathleen, Tebas, Pablo, Robbins, Gregory K., Roubenoff, Ronenn, Grinspoon, Steven K.

“…Background. Low testosterone levels are commonly reported in patients with advanced human immunodeficiency virus disease. The effects of initiation of…”
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Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children by Pussegoda, K, Ross, C J, Visscher, H, Yazdanpanah, M, Brooks, B, Rassekh, S R, Zada, Y F, Dubé, M-P, Carleton, B C, Hayden, M R

“…Cisplatin is a widely used chemotherapeutic agent for the treatment of solid tumors. A serious complication of cisplatin treatment is permanent hearing loss…”
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Novel presenilin mutations within Moroccan patients with Early-Onset Alzheimer’s Disease by El Kadmiri, N, Zaid, N, Zaid, Y, Tadevosyan, A, Hachem, A, Dubé, M.-P, Hamzi, K, El Moutawakil, B, Slassi, I, Nadifi, S

“…Highlights • We identified 1 novel mutation of presenilin 1 gene in 1 Moroccan EOAD case. • We detected 2 novel mutations of presenilin 2 gene in 2 Moroccan…”
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Protease inhibitor-associated hyperglycaemia by Dubé, M P, Johnson, D L, Currier, J S, Leedom, J M

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Methylomic changes during conversion to psychosis by Kebir, O, Chaumette, B, Rivollier, F, Miozzo, F, Lemieux Perreault, L P, Barhdadi, A, Provost, S, Plaze, M, Bourgin, J, Gaillard, R, Mezger, V, Dubé, M-P, Krebs, M-O

“…The onset of psychosis is the consequence of complex interactions between genetic vulnerability to psychosis and response to environmental and/or maturational…”
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Syringomyelia in cavalier King Charles spaniels: the relationship between syrinx dimensions and pain by Rusbridge, C, Carruthers, H, Dubé, M.-P, Holmes, M, Jeffery, N.D

“…This study was designed to test the hypothesis that pain associated with syringomyelia in dogs is dependent upon size and involvement of the dorsal part of the…”
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Cuckoo search epistasis: a new method for exploring significant genetic interactions by Aflakparast, M, Salimi, H, Gerami, A, Dubé, M-P, Visweswaran, S, Masoudi-Nejad, A

“…The advent of high-throughput sequencing technology has resulted in the ability to measure millions of single-nucleotide polymorphisms (SNPs) from thousands of…”
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Prospective Evaluation of the Effect of Initiating Indinavir-Based Therapy on Insulin Sensitivity and B-Cell Function in HIV-Infected Patients by Dubé, Michael P, Edmondson-Melançon, Hannah, Qian, Dajun, Aqeel, Rubina, Johnson, Debra, Buchanan, Thomas A

“…To determine whether initiation of antiretroviral therapy that includes the protease inhibitor indinavir causes insulin resistance or abnormal B-cell function…”
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Prophylaxis against Disseminated Mycobacterium avium Complex with Weekly Azithromycin, Daily Rifabutin, or Both by Havlir, Diane V, Dubé, Michael P, Sattler, Fred R, Forthal, Donald N, Kemper, Carol A, Dunne, Michael W, Parenti, David M, Lavelle, James P, White, A. Clinton, Witt, Mallory D, Bozzette, Samuel A, McCutchan, J. Allen

“…Unless they receive antimycobacterial prophylaxis in some form, up to 40 percent of patients have disseminated Mycobacterium avium complex infection within two…”
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A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13 by LEVCHENKO, A, PROVOST, S, ROULEAU, G. A, MONTPLAISIR, J.-Y, XIONG, L, ST-ONGE, J, THIBODEAU, P, RIVIERE, J.-B, DESAUTELS, A, TURECKI, G, DUBE, M.-P

“…The authors investigated genetic factors contributing to restless legs syndrome (RLS) by performing a 10-cM genome-wide scan in a large French-Canadian…”
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Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity by Carleton, B C, Ross, C J, Bhavsar, A P, Amstutz, U, Pussegoda, K, Visscher, H, Lee, J W, Brooks, B, Rassekh, S R, Dubé, M-P, Hayden, M R

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Tuberculous meningitis in patients with and without human immunodeficiency virus infection by Dubé, M P, Holtom, P D, Larsen, R A

“…To characterize the symptoms, signs, laboratory findings, and outcome of culture-proven meningitis due to Mycobacterium tuberculosis in patients with and…”
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A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials by de Denus, S, Rouleau, J L, Mann, D L, Huggins, G S, Cappola, T P, Shah, S H, Keleti, J, Zada, Y F, Provost, S, Bardhadi, A, Phillips, M S, Normand, V, Mongrain, I, Dubé, M-P

“…We conducted a meta-analysis of pharmacogenomic substudies of three randomized trials conducted in patients with decompensated heart failure (HF) that were led…”
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