Search Results - "Dube, D.K."

Refine Results
  1. 1

    Permissible amino acid substitutions within the putative nucleoside binding site of herpes simplex virus type 1 encoded thymidine kinase established by random sequence mutagenesis [corrected] by Munir, K M, French, D C, Dube, D K, Loeb, L A

    Published in The Journal of biological chemistry (05-04-1992)
    “…We determined the essentiality of all amino acid replacements within an 11-codon sequence in the putative nucleoside-binding site of thymidine kinase encoded…”
    Get full text
    Journal Article
  2. 2

    Molecular and immunohistochemical analyses of cardiac troponin T during cardiac development in the Mexican axolotl, Ambystoma mexicanum by Zhang, C., Pietras, K.M., Sferrazza, G.F., Jia, P., Athauda, G., Rueda-de-Leon, E., Maier, J.A., Dube, D.K., Lemanski, S.L., Lemanski, L.F.

    Published in Journal of cellular biochemistry (01-01-2007)
    “…The Mexican axolotl, Ambystoma mexicanum, is an excellent animal model for studying heart development because it carries a naturally occurring recessive…”
    Get full text
    Journal Article
  3. 3
  4. 4
  5. 5

    Downregulation of N1 gene expression inhibits the initial heartbeating and heart development in axolotls by Zhang, C, Meng, F, Huang, X.P, Zajdel, R, Lemanski, S.L, Foster, D, Erginel-Unaltuna, N, Dube, D.K, Lemanski, L.F

    Published in Tissue & cell (01-02-2004)
    “…Recessive mutant gene c in the axolotl results in a failure of affected embryos to develop contracting hearts. This abnormality can be corrected by treating…”
    Get full text
    Journal Article
  6. 6

    Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development by Meng, F., Huang, X.P., Zajdel, R.W., Foster, D., Dawson, N., Lemanski, S.L., Zawieja, D., Dube, D.K., Lemanski, L.F.

    Published in Tissue & cell (01-04-2003)
    “…The axolotl, Ambystoma mexicanum, is a useful system for studying embryogenesis and cardiogenesis. To understand the role of protein tyrosine phosphorylation…”
    Get full text
    Journal Article
  7. 7
  8. 8

    Molecular cloning, sequencing and expression of an isoform of cardiac alpha-tropomyosin from the Mexican axolotl (Ambystoma mexicanum) by Luque, E A, Lemanski, L F, Dube, D K

    “…The cDNA for alpha-tropomyosin (TM) was cloned by the polymerase chain reaction (PCR) from a lambda gt11 library constructed with mRNA from juvenile axolotl…”
    Get more information
    Journal Article
  9. 9
  10. 10

    Cloning, Sequencing and Expression of an Isoform of Cardiac C-Protein from the Mexican Axolotl ( Ambystoma mexicanum) by Ward, S.M., Lemanski, L.F., Eiginelunaltuna, N., Dube, D.K.

    “…C-protein, a myosin binding protein, is thought to regulate and stabilize thick filaments during assembly of sarcomeric A-bands. Multiple isoforms of C-protein…”
    Get full text
    Journal Article
  11. 11

    Selection of new biologically active molecules from random nucleotide sequences by Dube, D K, Black, M E, Munir, K M, Loeb, L A

    Published in Gene (1993)
    “…Genetic diversity can be achieved in vitro by inserting random nucleotide (nt) sequences into cloned genes. In the case of enzymes, subsequent genetic…”
    Get more information
    Journal Article
  12. 12

    Artificial mutants generated by the insertion of random oligonucleotides into the putative nucleoside binding site of the HSV-1 thymidine kinase gene by Dube, Dipak K, Parker, Jay D, French, David C, Cahill, David S, Dube, Syamalima, Horwitz, Marshall S. Z, Munir, Khan M, Loeb, Lawrence A

    Published in Biochemistry (Easton) (24-12-1991)
    “…We have obtained 42 active artificial mutants of HSV-1 thymidine kinase (ATP:thymidine 5'-phosphotransferase, EC 2.7.1.21) by replacing codons 166 and 167 with…”
    Get full text
    Journal Article
  13. 13
  14. 14

    Antitrypanosomal activity of sinefungin by Dube, D K, Mpimbaza, G, Allison, A C, Lederer, E, Rovis, L

    “…Sinefungin, a naturally occurring antifungal antibiotic nucleoside containing an ornithine residue, linked by a C-C bond to C-5' of adenosine, cures mice…”
    Get more information
    Journal Article
  15. 15
  16. 16
  17. 17
  18. 18

    On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization by Loeb, L A, Dube, D K, Beckman, R A, Koplitz, M, Gopinathan, K P

    Published in The Journal of biological chemistry (25-04-1981)
    “…During catalysis by homogeneous procaryotic DNA polymerases, nucleoside monophosphates are generated by a 3' leads to 5'-exonucleolytic activity. Using…”
    Get full text
    Journal Article
  19. 19

    Limitations of the Congo-Red staining techniques for the detection of cellulolytic activities by SHARMA, P, PAJNI, S, DHILLON, N, VADEHRA, D. V, DUBE, D. K

    Published in Biotechnology letters (01-08-1986)
    “…The interaction of Congo-Red with polysaccharide containing beta (1.4) or beta (1.3) linkages gives an intensely red complex whose formation is prevented by…”
    Get full text
    Journal Article
  20. 20