Search Results - "Dubé, Mathieu"

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? by Desforges, Marc, Le Coupanec, Alain, Dubeau, Philippe, Bourgouin, Andréanne, Lajoie, Louise, Dubé, Mathieu, Talbot, Pierre J

“…Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the…”
Get full text

Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43 by Dubé, Mathieu, Le Coupanec, Alain, Wong, Alan H M, Rini, James M, Desforges, Marc, Talbot, Pierre J

“…Human coronaviruses (HCoVs) are recognized respiratory pathogens for which accumulating evidence indicates that in vulnerable patients the infection can cause…”
Get full text

Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease by Morou, Antigoni, Brunet-Ratnasingham, Elsa, Dubé, Mathieu, Charlebois, Roxanne, Mercier, Eloi, Darko, Sam, Brassard, Nathalie, Nganou-Makamdop, Krystelle, Arumugam, Sahaana, Gendron-Lepage, Gabrielle, Yang, Lifei, Niessl, Julia, Baxter, Amy E., Billingsley, James M., Rajakumar, Premeela A., Lefebvre, François, Johnson, R. Paul, Tremblay, Cécile, Routy, Jean-Pierre, Wyatt, Richard T., Finzi, Andrés, Douek, Daniel C., Kaufmann, Daniel E.

“…Dysfunction of virus-specific CD4 + T cells in chronic human infections is poorly understood. We performed genome-wide transcriptional analyses and functional…”
Get full text

Calcium-Dependent Rubella Virus Fusion Occurs in Early Endosomes by Dubé, Mathieu, Etienne, Loïc, Fels, Maximilian, Kielian, Margaret

“…The E1 membrane protein of rubella virus (RuV) is a class II membrane fusion protein structurally related to the fusion proteins of the alphaviruses,…”
Get full text

Rubella virus: first calcium-requiring viral fusion protein by Dubé, Mathieu, Rey, Felix A, Kielian, Margaret

“…Rubella virus (RuV) infection of pregnant women can cause fetal death, miscarriage, or severe fetal malformations, and remains a significant health problem in…”
Get full text

Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells by Porichis, Filippos, Hart, Meghan G, Massa, Alexandra, Everett, Holly L, Morou, Antigoni, Richard, Jonathan, Brassard, Nathalie, Veillette, Maxime, Hassan, Muska, Ly, Ngoc Le, Routy, Jean-Pierre, Freeman, Gordon J, Dubé, Mathieu, Finzi, Andrés, Kaufmann, Daniel E

“…Immune exhaustion is an important feature of chronic infections, such as HIV, and a barrier to effective immunity against cancer. This dysfunction is in part…”
Get full text

Single-Cell Technologies Applied to HIV-1 Research: Reaching Maturity by Sannier, Gérémy, Dubé, Mathieu, Kaufmann, Daniel E

“…The need for definitive answers probably explains our natural tendency to seek simplicity. The reductionist "bulk" approach, in which a mean behavior is…”
Get full text

Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans-Golgi Network by DUBE, Mathieu, BHUSAN ROY, Bibhuti, GUIOT-GUILLAIN, Pierre, MERCIER, Johanne, BINETTE, Julie, LEUNG, Grace, COHEN, Eric A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses by Tauzin, Alexandra, Gong, Shang Yu, Beaudoin-Bussières, Guillaume, Vézina, Dani, Gasser, Romain, Nault, Lauriane, Marchitto, Lorie, Benlarbi, Mehdi, Chatterjee, Debashree, Nayrac, Manon, Laumaea, Annemarie, Prévost, Jérémie, Boutin, Marianne, Sannier, Gérémy, Nicolas, Alexandre, Bourassa, Catherine, Gendron-Lepage, Gabrielle, Medjahed, Halima, Goyette, Guillaume, Bo, Yuxia, Perreault, Josée, Gokool, Laurie, Morrisseau, Chantal, Arlotto, Pascale, Bazin, Renée, Dubé, Mathieu, De Serres, Gaston, Brousseau, Nicholas, Richard, Jonathan, Rovito, Roberta, Côté, Marceline, Tremblay, Cécile, Marchetti, Giulia C., Duerr, Ralf, Martel-Laferrière, Valérie, Kaufmann, Daniel E., Finzi, Andrés

“…The standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two doses administered three weeks apart. However, some public health authorities…”
Get full text

Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment by Dubé, Mathieu, Roy, Bibhuti Bhusan, Guiot-Guillain, Pierre, Binette, Julie, Mercier, Johanne, Chiasson, Antoine, Cohen, Eric A

“…The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an interferon-regulated restriction factor, which retains virions at the…”
Get full text

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System by Le Coupanec, Alain, Desforges, Marc, Meessen-Pinard, Mathieu, Dubé, Mathieu, Day, Robert, Seidah, Nabil G, Talbot, Pierre J

“…Human coronaviruses (HCoV) are respiratory pathogens that may be associated with the development of neurological diseases, in view of their neuroinvasive and…”
Get full text

Modulation of HIV-1-host interaction: role of the Vpu accessory protein by Dubé, Mathieu, Bego, Mariana G, Paquay, Catherine, Cohen, Éric A

“…Viral protein U (Vpu) is a type 1 membrane-associated accessory protein that is unique to human immunodeficiency virus type 1 (HIV-1) and a subset of related…”
Get full text

Targeting Mitochondria to Revive Dysfunctional Regulatory T Cells by Brunet-Ratnasingham, Elsa, Dubé, Mathieu, Kaufmann, Daniel E.

“…Immunometabolism is important to T cell dysfunction in chronic infections. A recent publication in The Journal of Clinical Investigation (2018;128:5083–5094)…”
Get full text

HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4 + T Cells by Prévost, Jérémie, Edgar, Cassandra R, Richard, Jonathan, Trothen, Steven M, Jacob, Rajesh Abraham, Mumby, Mitchell J, Pickering, Suzanne, Dubé, Mathieu, Kaufmann, Daniel E, Kirchhoff, Frank, Neil, Stuart J D, Finzi, Andrés, Dikeakos, Jimmy D

“…Along with other immune checkpoints, cell mmunoglobulin and ucin domain-containing protein (Tim-3) is expressed on exhausted CD4 and CD8 T cells and is…”
Get full text

BST2/tetherin inhibition of alphavirus exit by Ooi, Yaw Shin, Dubé, Mathieu, Kielian, Margaret

“…Alphaviruses such as chikungunya virus (CHIKV) and Semliki Forest virus (SFV) are small enveloped RNA viruses that bud from the plasma membrane. Tetherin/BST2…”
Get full text

Inner structure of anchor ice and ice dams in steep channels by Dubé, Mathieu, Turcotte, Benoit, Morse, Brian

“…Dynamic ice growth (composed primarily of anchor ice and ice dams) is the dominant process in steep (slope>0.3%) channels during winter. The ice growth (in all…”
Get full text

Rubella Virus: First Calcium-Requiring Viral Fusion Protein: e1004530 by Dubé, Mathieu, Rey, Felix A, Kielian, Margaret

“…Rubella virus (RuV) infection of pregnant women can cause fetal death, miscarriage, or severe fetal malformations, and remains a significant health problem in…”
Get full text

Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses by Prévost, Jérémie, Pickering, Suzanne, Mumby, Mitchell J, Medjahed, Halima, Gendron-Lepage, Gabrielle, Delgado, Gloria G, Dirk, Brennan S, Dikeakos, Jimmy D, Stürzel, Christina M, Sauter, Daniel, Kirchhoff, Frank, Bibollet-Ruche, Frederic, Hahn, Beatrice H, Dubé, Mathieu, Kaufmann, Daniel E, Neil, Stuart J D, Finzi, Andrés, Richard, Jonathan

“…The HIV-1 accessory protein Vpu enhances viral release by counteracting the restriction factor BST-2. Furthermore, Vpu promotes NK cell evasion by…”
Get full text

Les institutions culturelles, l’éducation, le numérique et la cocréation : entre médiation culturelle et médiation pédagogique by Thuot-Dubé, Mathieu

“…RésuméLa culture et l’éducation entretiennent des liens particuliers au Québec particulièrement depuis les années 1960. Depuis différents mandats…”
Get full text

HIV‐1 Vpu Antagonizes BST‐2 by Interfering Mainly with the Trafficking of Newly Synthesized BST‐2 to the Cell Surface by Dubé, Mathieu, Paquay, Catherine, Roy, Bibhuti Bhusan, Bego, Mariana G., Mercier, Johanne, Cohen, Éric A.

“…Bone marrow stromal cell antigen‐2 (BST‐2) inhibits human immunodeficiency virus type 1 (HIV‐1) release by cross‐linking nascent virions on infected cell…”
Get full text