Search Results - "Duarte, Madelaine"
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Neutrophil functional heterogeneity is a fixed phenotype and is associated with distinct gene expression profiles
Published in Journal of leukocyte biology (01-12-2022)“…Differences in the ability of neutrophils to perform relevant effector functions has been identified in a variety of disease states. Although neutrophil…”
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Journal Article -
2
Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes
Published in Blood (25-11-2021)“…Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder mediated by ultra-large immune complexes (ULICs) containing immunoglobulin G (IgG)…”
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3
Heterogeneity in neutrophil responses to immune complexes
Published in Blood advances (08-10-2019)“…Immune complexes (ICs) can trigger inflammation and thrombosis, in part, by activating neutrophils. Much attention has focused on the serologic characteristics…”
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4
Variation in Neutrophil Function Among Healthy Subjects Influences Response to Bacteria
Published in Blood (05-11-2020)“…Introduction: We have recently shown that healthy subjects have variable neutrophil degranulation responses to antigen/antibody immune complexes (ICs; Duarte…”
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Neutrophil Phenotypes Result in Differential Responses to Pathogens
Published in Blood (23-11-2021)“…▪ Introduction: We have previously reported that neutrophils from healthy subjects vary in their susceptibility to degranulate in response to immune complexes…”
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6
Complement Regulates the Procoagulant Effects of HIT Immune Complexes
Published in Blood (05-11-2020)“…Heparin induced thrombocytopenia (HIT) is a prothrombotic disorder mediated by ultra-large immune complexes (ULICs) containing IgG antibodies bound to…”
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Journal Article