Search Results - "Duarte, Joao M."
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The C57BL/6J mouse exhibits sporadic congenital portosystemic shunts
Published in PloS one (23-07-2013)“…C57BL/6 mice are the most widely used strain of laboratory mice. Using in vivo proton Magnetic Resonance Spectroscopy ((1)H MRS), we have repeatedly observed…”
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Modification upon aging of the density of presynaptic modulation systems in the hippocampus
Published in Neurobiology of aging (01-11-2009)“…Abstract Different presynaptic neuromodulation systems have been explored as possible targets to manage neurodegenerative diseases. However, most studies used…”
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A Multi-Pronged Approach to Adaptive and Context Aware Content Dissemination in VANETs
Published in Mobile networks and applications (01-10-2018)“…Content dissemination in Vehicular Ad-hoc Networks (VANETs) has the potential to enable a myriad of applications, ranging from advertising, traffic and…”
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4
Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal
Published in Aging and disease (01-02-2022)“…Diabetes impacts on brain metabolism, structure, and function. Alterations in brain metabolism have been observed in obesity and diabetes models induced by…”
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MobiVNDN: A distributed framework to support mobility in vehicular named-data networking
Published in Ad hoc networks (01-01-2019)“…In this work, we propose MobiVNDN, a distributed framework for Vehicular Named-Data networking (VNDN) communications. MobiVNDN focuses on mitigating the…”
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The relationship between the heart rate deflection point test and maximal lactate steady state
Published in Journal of sports medicine and physical fitness (01-05-2016)“…The aim of this study was to investigate the use of the Heart Rate Deflection Point Test (HRDP) in the determination of the velocity at the Maximal Lactate…”
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Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance
Published in Biochemical Society transactions (27-02-2023)“…The pathophysiological mechanisms intersecting metabolic and neurodegenerative disorders include insulin resistance, which has a strong involvement of…”
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High-fat diet consumption alters energy metabolism in the mouse hypothalamus
Published in International Journal of Obesity (01-06-2019)“…Background/Objectives High-fat diet consumption is known to trigger an inflammatory response in the hypothalamus, which has been characterized by an initial…”
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Magnetic Resonance Spectroscopy in Schizophrenia: Evidence for Glutamatergic Dysfunction and Impaired Energy Metabolism
Published in Neurochemical research (01-01-2019)“…In the past couple of decades, major efforts were made to increase reliability of metabolic assessments by magnetic resonance methods. Magnetic resonance…”
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Serine racemase modulation for improving brain insulin resistance: An Editorial Highlight for “Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid‐β oligomers”
Published in Journal of neurochemistry (01-10-2022)“…Abstract This Editorial highlights an interesting study in the current issue of the Journal of Neurochemistry in which Zhou et al. report new data showing that…”
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Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet
Published in Frontiers in neuroscience (08-01-2019)“…Metabolic syndrome and diabetes impact brain function and metabolism. While it is well established that rodents exposed to diets rich in saturated fat develop…”
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Brain energy metabolism: A roadmap for future research
Published in Journal of neurochemistry (01-05-2024)“…Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so…”
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Taurine Supplementation as a Neuroprotective Strategy upon Brain Dysfunction in Metabolic Syndrome and Diabetes
Published in Nutrients (18-03-2022)“…Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and function and constitute risk factors for cognitive impairment…”
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14
Deep thiopental anesthesia alters steady-state glucose homeostasis but not the neurochemical profile of rat cortex
Published in Journal of neuroscience research (01-02-2010)“…Barbiturates are regularly used as an anesthetic for animal experimentation and clinical procedures and are frequently provided with solubilizing compounds,…”
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Genetic deletion of hormone‐sensitive lipase in mice reduces cerebral blood flow but does not aggravate the impact of diet‐induced obesity on memory
Published in Journal of neurochemistry (01-05-2024)“…Hormone‐sensitive lipase (HSL) is active throughout the brain and its genetic ablation impacts brain function. Its activity in the brain was proposed to…”
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Brain Metabolism Alterations in Type 2 Diabetes: What Did We Learn From Diet-Induced Diabetes Models?
Published in Frontiers in neuroscience (20-03-2020)“…Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through mechanisms that include glucose toxicity, vascular damage and blood-brain…”
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High-fat and High-sucrose Diet-induced Hypothalamic Inflammation Shows Sex Specific Features in Mice
Published in Neurochemical research (01-12-2024)“…Hypothalamic inflammation underlies diet-induced obesity and diabetes in rodent models. While diet normalization largely allows for recovery from metabolic…”
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Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice
Published in PloS one (13-04-2012)“…Diabetic conditions are associated with modified brain function, namely with cognitive deficits, through largely undetermined processes. More than…”
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Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture
Published in Neurochemical research (01-10-2022)“…Sphingosine-1-phosphate (S1P) is best known for its roles as vascular and immune regulator. Besides, it is also present in the central nervous system (CNS)…”
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Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats
Published in Journal of neurochemistry (01-10-2009)“…Type 1 diabetes can affect hippocampal function triggering cognitive impairment through unknown mechanisms. Caffeine consumption prevents hippocampal…”
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