Search Results - "Duarte, João H"

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System by Stockinger, Brigitta, Meglio, Paola Di, Gialitakis, Manolis, Duarte, João H

“…The aryl hydrocarbon receptor (AhR), for many years almost exclusively studied by the pharmacology/toxicology field for its role in mediating the toxicity of…”
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Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions by Di Meglio, Paola, Duarte, João H., Ahlfors, Helena, Owens, Nick D.L., Li, Ying, Villanova, Federica, Tosi, Isabella, Hirota, Keiji, Nestle, Frank O., Mrowietz, Ulrich, Gilchrist, Michael J., Stockinger, Brigitta

“…Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other autoimmune diseases, but the mechanisms are largely unknown. Here we…”
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CAR-T cells tackle autoimmunity by Duarte, João H.

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Uncovering the global RNA virome by Duarte, João H.

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Fate mapping of IL-17-producing T cells in inflammatory responses by Potocnik, Alexandre J, Stockinger, Brigitta, Hirota, Keiji, Duarte, João H, Veldhoen, Marc, Hornsby, Eve, Li, Ying, Cua, Daniel J, Ahlfors, Helena, Wilhelm, Christoph, Tolaini, Mauro, Menzel, Ursula, Garefalaki, Anna

“…Although in vitro –generated cells of the T H 17 helper T cell subset are highly plastic, it is unclear whether T H 17 cells that develop in vivo retain their…”
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Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo by Duarte, João H, Di Meglio, Paola, Hirota, Keiji, Ahlfors, Helena, Stockinger, Brigitta

“…The aryl hydrocarbon receptor (AhR) has been attributed with anti-inflammatory effects in the development of pathological immune responses leading to…”
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IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection by Ahlfors, Helena, Morrison, Peter J, Duarte, João H, Li, Ying, Biro, Judit, Tolaini, Mauro, Di Meglio, Paola, Potocnik, Alexandre J, Stockinger, Brigitta

“…IL-22 is a cytokine that regulates tissue homeostasis at barrier surfaces. A variety of IL-22-producing cell types is known, but identification on the…”
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Regulation and function of innate and adaptive interleukin-17-producing cells by Hirota, Keiji, Ahlfors, Helena, Duarte, João H, Stockinger, Brigitta

“…Interleukin‐17 (IL‐17)‐mediated immune responses play a crucial role in the mucosal host defence against microbial and fungal pathogens. However, the chronic…”
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DNA cages target quantum dots by Duarte, João H.

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The aryl hydrocarbon receptor: fine-tuning the immune-response by Veldhoen, Marc, Duarte, João H

“…Triggers involved in the development of an autoimmune disease, and those that are part of determining its level of severity, are a major focus of current…”
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Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions by Duarte, João H, Zelenay, Santiago, Bergman, Marie-Louise, Martins, Ana C, Demengeot, Jocelyne

“…Induction of Forkhead-box p3 (Foxp3) expression in developing T cells upon peptide-MHC encountering has been proposed to define a lineage of committed Treg…”
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Tracing cell lineages with mutable barcodes by Duarte, João H

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CD8 T Cells and IFN-γ Emerge as Critical Players for Psoriasis in a Novel Model of Mouse Psoriasiform Skin Inflammation by Di Meglio, Paola, Duarte, João H.

“…A pathogenic crosstalk between epithelial and immune cells underpins the aberrant immune and epidermal responses seen in psoriasis. Data from a novel mouse…”
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The transcription factor E4BP4 is not required for extramedullary pathways of NK cell development by Crotta, Stefania, Gkioka, Annita, Male, Victoria, Duarte, João H, Davidson, Sophia, Nisoli, Ilaria, Brady, Hugh J M, Wack, Andreas

“…NK cells contribute to antitumor and antiviral immunosurveillance. Their development in the bone marrow (BM) requires the transcription factor E4BP4/NFIL3, but…”
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Selective knockout of gut bacteria by Duarte, João H

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Enhancing seed protein content by Duarte, João H

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Cutting edge: Intrathymic differentiation of adaptive Foxp3+ regulatory T cells upon peripheral proinflammatory immunization by Zelenay, Santiago, Bergman, Marie-Louise, Paiva, Ricardo Sousa, Lino, Andreia C, Martins, Ana C, Duarte, João H, Moraes-Fontes, Maria F, Bilate, Angelina M, Lafaille, Juan J, Demengeot, Jocelyne

“…Thymocytes differentiate into CD4(+) Foxp3(+) regulatory T cells (T(R)) upon interaction between their TCR and peptide-MHC II complexes locally expressed in…”
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Osteoarthritis: Autophagy prevents age-related OA by Duarte, João H

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Spondyloarthropathies: IL-17A blockade ameliorates ankylosing spondylitis by Duarte, João H

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Rheumatoid arthritis: Osteoclasts and ACPAs--the joint link by Duarte, João H

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