Search Results - "Duarte, Diana"

Drug Repurposing in Cancer Therapy: Influence of Patient's Genetic Background in Breast Cancer Treatment by Rodrigues, Rafaela, Duarte, Diana, Vale, Nuno

“…Cancer is among the leading causes of death worldwide and it is estimated that in 2040 more than 29 million people will be diagnosed with some type of cancer…”
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Synergistic Growth Inhibition of HT-29 Colon and MCF-7 Breast Cancer Cells with Simultaneous and Sequential Combinations of Antineoplastics and CNS Drugs by Duarte, Diana, Cardoso, Armando, Vale, Nuno

“…Several central nervous system (CNS) drugs exhibit potent anti-cancer activities. This study aimed to design a novel model of combination that combines…”
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Synergistic Interaction of CPP2 Coupled with Thiazole Derivates Combined with Clotrimazole and Antineoplastic Drugs in Prostate and Colon Cancer Cell Lines by Duarte, Diana, Vale, Nuno

“…Cell-penetrating peptides (CPPs) are small peptide sequences used mainly as cellular delivery agents that are able to efficiently deliver cargo into cells…”
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New Trends for Antimalarial Drugs: Synergism between Antineoplastics and Antimalarials on Breast Cancer Cells by Duarte, Diana, Vale, Nuno

“…Chemotherapy plays a key role in breast cancer therapy, but drug resistance and unwanted side effects make the treatment less effective. We propose a new…”
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Antidepressant Drug Sertraline against Human Cancer Cells by Duarte, Diana, Vale, Nuno

“…The use of FDA-approved drugs for new indications represents a faster and more economical way to find novel therapeutic agents for cancer therapy, compared to…”
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How Antimalarials and Antineoplastic Drugs can Interact in Combination Therapies: A Perspective on the Role of PPT1 Enzyme by Duarte, Diana, Vale, Nuno

“…Antimalarial drugs from different classes have demonstrated anticancer effects in different types of cancer cells, but their complete mode of action in cancer…”
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The Antineoplastic Effect of Carboplatin Is Potentiated by Combination with Pitavastatin or Metformin in a Chemoresistant High-Grade Serous Carcinoma Cell Line by Nunes, Mariana, Duarte, Diana, Vale, Nuno, Ricardo, Sara

“…The combination of Carboplatin with Paclitaxel is the mainstay treatment for high-grade serous carcinoma; however, many patients with advanced disease undergo…”
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Antipsychotic Drug Fluphenazine against Human Cancer Cells by Duarte, Diana, Vale, Nuno

“…Drug repurposing is a strategy that can speed up and find novel clinical uses for already-approved drugs for several diseases, such as cancer. This process is…”
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Novel Strategies for Cancer Combat: Drug Combination Using Repurposed Drugs Induces Synergistic Growth Inhibition of MCF-7 Breast and HT-29 Colon Cancer Cells by Duarte, Diana, Guerreiro, Inês, Vale, Nuno

“…Our group developed a new model of drug combination consisting of the use of antineoplastic drugs and different repurposed drugs, having demonstrated that…”
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Evaluation of synergism in drug combinations and reference models for future orientations in oncology by Duarte, Diana, Vale, Nuno

“…Current cancer therapy includes a variety of strategies that can comprise only one type of treatment or a combination of multiple treatments. Chemotherapy is…”
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Hydrodeoxygenation of 5‑Hydroxymethylfurfural over Alumina-Supported Catalysts in Aqueous Medium by Duarte, Diana P, Martínez, Ramiro, Hoyos, Luis J

“…Catalytic activity and selectivity of Ni, Pd, and Cu supported on γ-alumina catalysts for the 5-hydroxymethylfurfural hydrodeoxygenation in aqueous phase were…”
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Combination of Antimalarial and CNS Drugs with Antineoplastic Agents in MCF-7 Breast and HT-29 Colon Cancer Cells: Biosafety Evaluation and Mechanism of Action by Duarte, Diana, Nunes, Mariana, Ricardo, Sara, Vale, Nuno

“…Drug combination and drug repurposing are two strategies that allow to find novel oncological therapies, in a faster and more economical process. In our…”
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Prediction of Drug Synergism between Peptides and Antineoplastic Drugs Paclitaxel, 5-Fluorouracil, and Doxorubicin Using In Silico Approaches by Vale, Nuno, Pereira, Mariana, Santos, Joana, Moura, Catarina, Marques, Lara, Duarte, Diana

“…Chemotherapy is the main treatment for most early-stage cancers; nevertheless, its efficacy is usually limited by drug resistance, toxicity, and tumor…”
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Improvement of the in vitro cytotoxic effect on HT-29 colon cancer cells by combining 5-fluorouacil and fluphenazine with green, red or brown propolis by Falcão, Soraia I., Duarte, Diana, Diallo, Moustapha, Santos, Joana B., Ribeiro, Eduarda, Vale, Nuno, Vilas-Boas, Miguel

“…Cancer is regard as one of the key factors of mortality and morbidity in the world. Treatment is mainly based on chemotherapeutic drugs that, when used in…”
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Metastatic Insulinoma With Refractory Hypoglycemia With Complete Response to Peptide Receptor Radionuclide Therapy by Borges Duarte, Diana, Elvas, Ana Rita, Couto, Joana, Domingues, Isabel, Oliveira, Sofia, G. Martins, Raquel

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Drug Combinations: A New Strategy to Extend Drug Repurposing and Epithelial-Mesenchymal Transition in Breast and Colon Cancer Cells by Duarte, Diana, Rêma, Alexandra, Amorim, Irina, Vale, Nuno

“…Despite the progressive research and recent advances in drug therapy to treat solid tumours, the number of cases and deaths in patients with cancer is still a…”
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Maternal Hypertriglyceridemia in Gestational Diabetes: A New Risk Factor? by Marques Puga, Francisca, Borges Duarte, Diana, Benido Silva, Vânia, Pereira, Maria Teresa, Garrido, Susana, Vilaverde, Joana, Sales Moreira, Marta, Pichel, Fernando, Pinto, Clara, Dores, Jorge

“…Elevated maternal triglycerides (TGs) have been associated with excessive fetal growth. However, the role of maternal lipid profile is less studied in…”
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New Peptide Functionalized Nanostructured Lipid Carriers with CNS Drugs and Evaluation Anti-proliferative Activity by Silva, Sara, Marto, Joana, Gonçalves, Lídia M., Duarte, Diana, Soares, O. Salomé G. P., Vasques-Nóvoa, Francisco, Almeida, António J., Vale, Nuno

“…Nanoparticulate systems have been widely investigated as delivery vectors for efficient drug delivery in different diseases. Nanostructured lipid carriers…”
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Assessing the reproducibility and predictive value of objective cough measurement for successful withdrawal of invasive ventilatory support in adult patients by Varón-Vega, Fabio, Rincón, Adriana, Giraldo-Cadavid, Luis F, Tuta-Quintero, Eduardo, Palacios, Jonathan, Crevoisier, Stephanie, Duarte, Diana C, Poveda, Marcela, Cucunubo, Laura, Monedero, Pablo

“…Utilizing clinical tests, such as objective cough measurement, can assist in predicting the success of the weaning process in critically ill patients. A…”
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Honeybee Venom Synergistically Enhances the Cytotoxic Effect of CNS Drugs in HT-29 Colon and MCF-7 Breast Cancer Cell Lines by Duarte, Diana, Falcão, Soraia I, El Mehdi, Iouraouine, Vilas-Boas, Miguel, Vale, Nuno

“…5-fluorouracil (5-FU) and doxorubicin (DOX) are potent anti-tumour agents commonly used for colon and breast cancer therapy, respectively. However, their…”
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