Search Results - "Duara, R"

Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease by DUARA, R, LOEWENSTEIN, D. A, SCHOFIELD, E, WU, Y, POTTER, H, POTTER, E, APPEL, J, GREIG, M. T, URS, R, SHEN, Q, RAJ, A, SMALL, B, BARKER, W

“…Despite convenience, accessibility, and strong correlation to severity of Alzheimer disease (AD) pathology, medial temporal lobe atrophy (MTA) has not been…”
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Effect of age, ethnicity, sex, cognitive status and APOE genotype on amyloid load and the threshold for amyloid positivity by Duara, R, Loewenstein, D A, Lizarraga, G, Adjouadi, M, Barker, W W, Greig-Custo, M T, Rosselli, M, Penate, A, Shea, Y F, Behar, R, Ollarves, A, Robayo, C, Hanson, K, Marsiske, M, Burke, S, Ertekin-Taner, N, Vaillancourt, D, De Santi, S, Golde, T, St, DeKosky

“…The threshold for amyloid positivity by visual assessment on PET has been validated by comparison to amyloid load measured histopathologically and…”
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Pathology and temporal onset of visual hallucinations, misperceptions and family misidentification distinguishes dementia with Lewy bodies from Alzheimer's disease by Ferman, T.J, Arvanitakis, Z, Fujishiro, H, Duara, R, Parfitt, F, Purdy, M, Waters, C, Barker, W, Graff-Radford, N.R, Dickson, D.W

“…Abstract Objective To determine whether the temporal onset of visual phenomena distinguishes Lewy body disease (LBD) from Alzheimer's disease (AD), and to…”
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Mild cognitive impairment: directions for future research by Luis, C A, Loewenstein, D A, Acevedo, A, Barker, W W, Duara, R

“…Mild cognitive impairment (MCI), an intermediate state between normal aging and dementia, is characterized by acquired cognitive deficits, without significant…”
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Neuropathologic Features of Frontotemporal Lobar Degeneration With Ubiquitin-Positive Inclusions With Progranulin Gene (PGRN) Mutations by Josephs, Keith A, Ahmed, Zeshan, Katsuse, Omi, Parisi, Joseph F, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Davies, Peter, Duara, Ranjan, Graff-Radford, Neill R, Uitti, Ryan J, Rademakers, Rosa, Adamson, Jennifer, Baker, Matthew, Hutton, Michael L, Dickson, Dennis W

“…Frontotemporal lobar degeneration is heterogeneous; cases with tau- and synuclein-negative, ubiquitin-positive neuronal inclusions are the most common, and…”
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Head injury and the risk of AD in the MIRAGE study by GUO, Z, CUPPLES, L. A, JOHNSON, K, GO, R. C, GROWDON, J. H, HAINES, J. L, KUKULL, W. A, FARRER, L. A, KURZ, A, AUERBACH, S. H, VOLICER, L, CHUI, H, GREEN, R. C, SADOVNICK, A. D, DUARA, R, DECARLI, C

“…It has been suggested in some studies that head injury is a risk factor for AD, and that this risk is heightened among carriers of the APOE-epsilon4 allele. We…”
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Association of White Matter Hyperintensity Measurements on Brain MR Imaging with Cognitive Status, Medial Temporal Atrophy, and Cardiovascular Risk Factors by Appel, J, Potter, E, Bhatia, N, Shen, Q, Zhao, W, Greig, M.T, Raj, A, Barker, W.W, Potter, H, Schofield, E, Wu, Y, Loewenstein, D.A, Duara, R

“…White matter hyperintensities (WMHs) are frequently characterized as markers of cerebrovascular disease, whereas medial temporal atrophy (MTA) is a recognized…”
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Factors related to medication adherence in memory disorder clinic patients by Ownby, R. L., Hertzog, C., Crocco, E., Duara, R.

“…Medication adherence is a substantial problem in the elderly. It may be even more important among elderly persons with memory problems, since other factors…”
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A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease by CRAWFORD, F. C, FREEMAN, M. J, ANAND, R, MULLAN, M. J, SCHINKA, J. A, ABDULLAH, L. I, GOLD, M, HARTMAN, R, KRIVIAN, K, MORRIS, M. D, RICHARDS, D, DUARA, R

“…To investigate whether or not a coding polymorphism in the cystatin C gene (CST3) contributes risk for AD. A case-control genetic association study of a…”
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Family history of dementia is a risk factor for Lewy body disease by Woodruff, B K, Graff-Radford, N R, Ferman, T J, Dickson, D W, DeLucia, M W, Crook, J E, Arvanitakis, Z, Brassler, S, Waters, C, Barker, W, Duara, R

“…Genetic factors are important in Alzheimer disease (AD) and Parkinson disease but have not been well characterized in Lewy body dementia (LBD). The authors…”
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Correction of coarctation of aorta in adult patients--impact of corrective procedure on long-term recoarctation and systolic hypertension by Duara, R, Theodore, S, Sarma, P S, Unnikrishnan, M, Neelakandhan, K S

“…Uncorrected coarctation of the aorta in adults predisposes to congestive failure, aortic rupture, stroke and endocarditis. Surgical correction of this…”
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Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study : What is in store for the oldest old ? by LAUTENSCHLAGER, N. T, CUPPLES, L. A, GREEN, R. C, JONES, R, KARLINSKY, H, KUKULL, W. A, KURZ, A, LARSON, E. B, MARTELLI, K, SADOVNICK, A. D, VOLICER, L, WARING, S. C, RAO, V. S, GROWDON, J. H, FARRER, L. A, AUERBACH, S. A, BECKER, R, BURKE, J, CHUI, H, DUARA, R, FOLEY, E. J, GLATT, S. L

“…Despite recent advances in the molecular genetics of Alzheimer's disease (AD), several fundamental questions concerning risk of illness are unresolved, namely,…”
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Confirmation of association between D10S583 and Alzheimer's disease in a case–control sample by Ait-Ghezala, G, Abdullah, L, Crescentini, R, Crawford, F, Town, T, Singh, S, Richards, D, Duara, R, Mullan, M

“…Several independent studies have reported that loci on chromosome 10 are associated/linked with Alzheimer's disease (AD), including a family-based study…”
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Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14 by Mortilla, M, Farrer, L, Liang, Y, Duara, R, St George-Hyslop, P, Sorbi, S, Vaula, G, Rogaev, E, Cantu, J-M, Bergamini, L, Macciardi, F, Rogaeva, E, Pericak-Vance, M, Schlumpf, K, Tsuda, T, Haines, J, Tanzi, R, Nee, L, Rainero, I, Alexandrova, N, Kennedy, J, Pollen, D, Amaducci, L, Polinsky, R, Bruni, A, Roses, A, Lukiw, W, Crapper McLachlan, D, Pinessi, L, Foncin, J-F, Montesi, M, Gusella, J

“…Familial Alzheimer's disease (FAD) has been shown to be genetically heterogeneous, with a very small proportion of early onset pedigrees being associated with…”
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Alzheimer's disease: Interaction of apolipoprotein E genotype, family history of dementia, gender, education, ethnicity, and age of onset by Duara, R, Barker, W W, Lopez-Alberola, R, Loewenstein, D A, Grau, L B, Gilchrist, D, Sevush, S, St. George-Hyslop, P H

“…We evaluated 197 patients with predominantly late-onset Alzheimer's disease (AD) who belonged to several ethnic groups and analyzed the relationship of age of…”
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Four distinct trajectories of tau deposition identified in Alzheimer’s disease by Vogel, Jacob W., Young, Alexandra L., Oxtoby, Neil P., Smith, Ruben, Ossenkoppele, Rik, Strandberg, Olof T., La Joie, Renaud, Aksman, Leon M., Grothe, Michel J., Iturria-Medina, Yasser, Pontecorvo, Michael J., Devous, Michael D., Rabinovici, Gil D., Alexander, Daniel C., Lyoo, Chul Hyoung, Evans, Alan C., Hansson, Oskar

“…Alzheimer’s disease (AD) is characterized by the spread of tau pathology throughout the cerebral cortex. This spreading pattern was thought to be fairly…”
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Positron emission tomography in Alzheimer's disease by DUARA, R, GRADY, C, HAXBY, J, SUNDARAM, M, CUTLER, N. R, HESTON, L, MOORE, A, SCHLAGETER, N, LARSON, S, RAPOPORT, S. I

“…Twenty-one patients with a clinical diagnosis of dementia of the Alzheimer's type (DAT) and 29 healthy, age-matched controls were studied using positron…”
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A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics by HARWOOD, D. G, BARKER, W. W, LOEWENSTEIN, D. A, OWNBY, R. L, GEORGE-HYSLOP, P. S, MULLAN, M, DUARA, R

“…The prevalence of AD appears to vary widely in different ethnic groups. Certain risk factors for AD are well established for the general population, but there…”
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A comparison of familial and sporadic Alzheimer's disease by DUARA, R, LOPEZ-ALBEROLA, R. F, BARKER, W. W, LOEWENSTEIN, D. A, ZATINSKY, M, EISDORFER, C. E, WEINBERG, G. B

“…Using a liberal criterion, a conservative probability-based criterion, and a criterion for autosomal dominant inheritance, we classified 36%, 13.5%, and 6.4%…”
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The genetic association between Cathepsin D and Alzheimer's disease by Crawford, F.C, Freeman, M.J, Schinka, J, Abdullah, L.I, Richards, D, Sevush, S, Duara, R, Mullan, M.J

“…The aspartyl protease Cathepsin D has previously been suggested to play a role in the Alzheimer's disease (AD) process because of its ability to cleave the…”
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